公开(公告)号：US11311547B2

公开(公告)日：2022-04-26

申请号：US17303229

申请日：2021-05-24

Applicant: Board of Regents of the University of Nebraska

Inventor： Howard Gendelman ,  Benson Edagwa

IPC: A61K31/495 ,  A61K31/505 ,  A61K9/14 ,  A61K31/5365 ,  A61P31/18 ,  A61K9/00 ,  A61K9/16 ,  A61K31/519

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US11166957B2

公开(公告)日：2021-11-09

申请号：US17303228

申请日：2021-05-24

Applicant: Board of Regents of the University of Nebraska

Inventor： Howard Gendelman ,  Benson Edagwa

IPC: A61K31/505 ,  A61K31/5365 ,  A61P31/18 ,  A61K9/00 ,  A61K9/16 ,  A61K31/519

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US12168013B2

公开(公告)日：2024-12-17

申请号：US17655483

申请日：2022-03-18

Applicant: Board of Regents of the University of Nebraska

Inventor： Howard Gendelman ,  Benson Edagwa

IPC: A61K31/5365 ,  A61K9/00 ,  A61K9/16 ,  A61K31/519 ,  A61P31/18

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US20220288037A1

公开(公告)日：2022-09-15

申请号：US17631955

申请日：2020-08-21

Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

Inventor： Benson Edagwa ,  Howard Gendelman

IPC: A61K31/426 ,  A61P31/12 ,  A61K31/675

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US20220211716A1

公开(公告)日：2022-07-07

申请号：US17655483

申请日：2022-03-18

Applicant: Board of Regents of the University of Nebraska

Inventor： Howard Gendelman ,  Benson Edagwa

IPC: A61K31/5365 ,  A61P31/18 ,  A61K9/00 ,  A61K9/16 ,  A61K31/519

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US20210322425A1

公开(公告)日：2021-10-21

申请号：US17303229

申请日：2021-05-24

Applicant: Board of Regents of the University of Nebraska

Inventor： Howard Gendelman ,  Benson Edagwa

IPC: A61K31/5365 ,  A61P31/18 ,  A61K9/00 ,  A61K9/16

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US20210213023A1

公开(公告)日：2021-07-15

申请号：US17301030

申请日：2021-03-22

Applicant: Board of Regents of the University of Nebraska

Inventor： Howard Gendelman ,  Benson Edagwa

IPC: A61K31/5365 ,  A61P31/18 ,  A61K9/00 ,  A61K9/16

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US20210060138A1

公开(公告)日：2021-03-04

申请号：US16812140

申请日：2020-03-06

Applicant: Temple University - of the Commonwealth System of Higher Education ,  BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

Inventor： Kamel Khalili ,  Howard E. Gendelman ,  Benson Edagwa

IPC: A61K38/46 ,  A61K35/761 ,  A61P31/18 ,  A61K31/5365 ,  A61K31/7068 ,  A61K31/7076 ,  A61K31/505 ,  A61K31/7105

Abstract: Methods of eliminating a retrovirus from a subject utilize nanoformulated anti-retroviral compounds and gene editing agents. Compositions comprise at least one anti-retroviral compounds, at least one gene-editing agent, or combinations thereof.