公开(公告)号：US20210403962A1

公开(公告)日：2021-12-30

申请号：US17472028

申请日：2021-09-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyo Jin KIM ,  Lan HUH ,  Sang Jo LIM ,  Hyun Ah KIM ,  Hyoung Joon KIM ,  Chang il SEO ,  Seung Bin LEE ,  Ji Sun LEE

IPC: C12P13/06 ,  C12N1/20 ,  C12N9/04 ,  C12P13/08 ,  C12P13/12

Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.

公开(公告)号：US20210317488A1

公开(公告)日：2021-10-14

申请号：US16633461

申请日：2019-07-25

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Seok Myung LEE ,  Ki Yong CHEONG ,  Chang II SEO ,  Ji Sun LEE

IPC: C12P13/22 ,  C07K14/245 ,  C12P13/08 ,  C12N1/20 ,  C12N15/70

Abstract: Provided are a cAMP receptor protein variant, a microorganism including the same, and a method of producing an L-amino acid using the same.

公开(公告)号：US20200048619A1

公开(公告)日：2020-02-13

申请号：US16534130

申请日：2019-08-07

Applicant: CJ CheilJedang Corporation

Inventor： Ji Sun LEE ,  Dong Eun CHANG ,  So Young KIM

IPC: C12N9/12 ,  C12N15/70 ,  C12P21/00 ,  C12P19/34 ,  C12P19/04 ,  C12P7/64

Abstract: A nucleic acid molecule comprising a variant rpoC coding sequence is disclosed. The variant rpoC coding sequence encodes a variant RpoC which regulates copy number of a plasmid. Also disclosed are a recombinant microorganism comprising the nucleic acid molecule, a method for regulating copy number of a subject vector in the recombinant microorganism, and a method for making a target product by use of the recombinant microorganism.

公开(公告)号：US20170002388A1

公开(公告)日：2017-01-05

申请号：US15112855

申请日：2015-03-17

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Eun Sung KOH ,  Su Yon KWON ,  Kwang Ho LEE ,  Ji Sun LEE ,  Juno JANG ,  Keun Cheol LEE ,  Hyeong Pyo HONG

IPC: C12P13/22 ,  C12N9/24 ,  C12P13/08 ,  C12N9/78

CPC classification number: C12P13/227 ,  C12N9/2497 ,  C12N9/78 ,  C12P13/08 ,  C12Y302/02004 ,  C12Y305/04004

Abstract: Disclosed are a recombinant microorganism having enhanced L-amino acid productivity, wherein the recombinant microorganism is transformed to have removed or decreased activity of at least one of adenosine deaminase and AMP nucleosidase, and a method of producing an L-amino acid using the recombinant microorganism. The use of the recombinant microorganism may enable the production of the L-amino acid in a highly efficient manner.

Abstract translation: 公开了具有增强的L-氨基酸生产力的重组微生物，其中转化重组微生物以去除或降低腺苷脱氨酶和AMP核苷酶中的至少一种的活性，以及​​使用重组微生物产生L-氨基酸的方法 。 重组微生物的使用可以以高效的方式生产L-氨基酸。

公开(公告)号：US20170002365A1

公开(公告)日：2017-01-05

申请号：US15112992

申请日：2014-04-25

Applicant: CJ Cheiljedang Corporation

Inventor： Hyung Joon KIM ,  Su Yon KWON ,  Eun Sung KOH ,  Ji Sun LEE ,  Keun Cheol LEE ,  Young Bin HWANG ,  Hyeong Pyo HONG

IPC: C12N15/70 ,  C07K14/34 ,  C12P13/08

CPC classification number: C12N15/70 ,  C07K14/34 ,  C12N1/20 ,  C12P13/08

Abstract: The present invention relates to an E. coli mutant strain having enhanced L-threonine productivity, which is obtained by introducing the permease of Corynebacterium origin, and to method of producing L-threonine using the E. coli mutant strain.

Abstract translation: 本发明涉及通过引入源自棒杆菌的通透酶获得的具有增强的L-苏氨酸生产力的大肠杆菌突变菌株，以及使用大肠杆菌突变株产生L-苏氨酸的方法。