公开(公告)号：US20180087077A1

公开(公告)日：2018-03-29

申请号：US15573236

申请日：2016-05-10

Applicant: CJ Cheiljedang Corporation

Inventor： Seok Myung LEE ,  Baek Seok LEE ,  Kyungrim KIM ,  Kwang Ho LEE ,  Keun Cheol LEE ,  Hyeongpyo HONG

IPC: C12P13/22 ,  C12N1/20

CPC classification number: C12P13/227 ,  C12N1/20 ,  C12N15/70 ,  C12P13/14

Abstract: The present invention relates to a microorganism of the genus Escherichia in which L-tryptophan productivity is improved by inactivating phosphatase activity. Further, the present invention relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.

公开(公告)号：US20170137854A1

公开(公告)日：2017-05-18

申请号：US15321717

申请日：2015-06-23

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ki Yong CHEONG ,  Kyung Rim KIM ,  Seok Myung LEE ,  Kwang Ho LEE ,  Keun Cheol LEE ,  Hyeong Pyo HONG

IPC: C12P13/22 ,  C12N9/88 ,  C12N15/52

Abstract: The present application relates to a microorganism of the genus Escherichia producing L-tryptophan and, more specifically, to a microorganism of the genus Escherichia with improved activity of producing L-tryptophan by weakening or inactivating the activity of endogenous 6-phosphogluconate dehydratase and 2-keto-3-deoxy-6-phosphogluconate aldolase.Additionally, the present application relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.

公开(公告)号：US20180127792A1

公开(公告)日：2018-05-10

申请号：US15573244

申请日：2016-05-10

Applicant: CJ Cheiljedang Corporation

Inventor： Hye Min PARK ,  Baek Seok LEE ,  Seok Myung LEE ,  Kyungrim KIM ,  Kwang Ho LEE ,  Ki Yong CHEONG ,  Keun Cheol LEE ,  Hyeongpyo HONG

IPC: C12P13/22 ,  C12N15/71 ,  C12N9/16

CPC classification number: C12P13/227 ,  C12N9/16 ,  C12N15/71 ,  C12Y301/03

Abstract: The present disclosure relates to a microorganism of the genus Escherichia producing more L-tryptophan by inactivating the activity of phosphatase.Additionally, the present disclosure relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.

公开(公告)号：US20170081633A1

公开(公告)日：2017-03-23

申请号：US15312497

申请日：2015-04-14

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Juno JANG ,  Hye Min PARK ,  Kwang Ho LEE ,  Keun Cheol LEE ,  Hyeong Pyo HONG

IPC: C12N1/20 ,  C12P13/22

CPC classification number: C12N1/20 ,  C07K14/245 ,  C12P13/04 ,  C12P13/08 ,  C12P13/227

Abstract: The present application relates to a recombinant microorganism having an improved intracellular energy level and a method for producing L-amino acid using the microorganism.

公开(公告)号：US20170002388A1

公开(公告)日：2017-01-05

申请号：US15112855

申请日：2015-03-17

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Eun Sung KOH ,  Su Yon KWON ,  Kwang Ho LEE ,  Ji Sun LEE ,  Juno JANG ,  Keun Cheol LEE ,  Hyeong Pyo HONG

IPC: C12P13/22 ,  C12N9/24 ,  C12P13/08 ,  C12N9/78

CPC classification number: C12P13/227 ,  C12N9/2497 ,  C12N9/78 ,  C12P13/08 ,  C12Y302/02004 ,  C12Y305/04004

Abstract: Disclosed are a recombinant microorganism having enhanced L-amino acid productivity, wherein the recombinant microorganism is transformed to have removed or decreased activity of at least one of adenosine deaminase and AMP nucleosidase, and a method of producing an L-amino acid using the recombinant microorganism. The use of the recombinant microorganism may enable the production of the L-amino acid in a highly efficient manner.

Abstract translation: 公开了具有增强的L-氨基酸生产力的重组微生物，其中转化重组微生物以去除或降低腺苷脱氨酶和AMP核苷酶中的至少一种的活性，以及​​使用重组微生物产生L-氨基酸的方法 。 重组微生物的使用可以以高效的方式生产L-氨基酸。

公开(公告)号：US20170002365A1

公开(公告)日：2017-01-05

申请号：US15112992

申请日：2014-04-25

Applicant: CJ Cheiljedang Corporation

Inventor： Hyung Joon KIM ,  Su Yon KWON ,  Eun Sung KOH ,  Ji Sun LEE ,  Keun Cheol LEE ,  Young Bin HWANG ,  Hyeong Pyo HONG

IPC: C12N15/70 ,  C07K14/34 ,  C12P13/08

CPC classification number: C12N15/70 ,  C07K14/34 ,  C12N1/20 ,  C12P13/08

Abstract: The present invention relates to an E. coli mutant strain having enhanced L-threonine productivity, which is obtained by introducing the permease of Corynebacterium origin, and to method of producing L-threonine using the E. coli mutant strain.

Abstract translation: 本发明涉及通过引入源自棒杆菌的通透酶获得的具有增强的L-苏氨酸生产力的大肠杆菌突变菌株，以及使用大肠杆菌突变株产生L-苏氨酸的方法。