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公开(公告)号：US20170121351A1
公开(公告)日：2017-05-04
申请号：US15319756
申请日：2014-06-18
Applicant: Colgate-Palmolive Company
Inventor： Shiri Nawrocki , Ravi SUBRAMANYAM , Long PAN
IPC: C07F3/06
CPC classification number: C07F3/06 , C07B2200/13 , C07F3/003
Abstract: The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl−, in which zinc chloride is reacted with lysine, in aqueous solution. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.
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公开(公告)号：US20210085583A1
公开(公告)日：2021-03-25
申请号：US16955308
申请日：2017-12-19
Applicant: Colgate-Palmolive Company
Inventor： Zhigang HAO , Chi-Yuan CHENG , Long PAN , Ravi SUBRAMANYAM
Abstract: The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C22H32Cl2N10][C6H12NO3S]2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.
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公开(公告)号：US20190274936A1
公开(公告)日：2019-09-12
申请号：US16425122
申请日：2019-05-29
Applicant: Colgate-Palmolive Company
Inventor： Baohua QIAO , Long PAN , Gregory SZEWCZYK , Ravi SUBRAMANYAM , Shiri NAWROCKI , Viktor DUBOVOY
Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an organic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the organic zinc salt and long chain polyphosphates being mixed in amounts that provide a phosphorus to zinc mole ratio of 15:1 to about 55:1. Further provided is a method of making this soluble zinc polyphosphate.
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公开(公告)号：US20170348352A1
公开(公告)日：2017-12-07
申请号：US15538330
申请日：2014-12-26
Applicant: Colgate-Palmolive Company
Inventor： Baohua QIAO , Long PAN , Gregory SZEWCZYK , Ravi SUBRAMANYAM
CPC classification number: A61K33/42 , A61K6/0017 , A61K6/0082 , A61K8/24 , A61K8/27 , A61K9/0063 , A61K33/30 , A61K2800/262 , A61K2800/58 , A61Q11/00 , A61Q15/00 , C01B25/37 , A61K2300/00
Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an inorganic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of making this soluble zinc polyphosphate.
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公开(公告)号：US20170340534A1
公开(公告)日：2017-11-30
申请号：US15539725
申请日：2014-12-26
Applicant: Colgate-Palmolive Company
Inventor： Shiri NAWROCKI , Viktor DUBOVOY , Long PAN , Baohua QIAO , Gregory SZEWCZYK , Ravi SUBRAMANYAM
Abstract: An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including a zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and a solvent, the relative amount of organic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.
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Patent Agency Ranking
公开(公告)号：US20170172875A1
公开(公告)日：2017-06-22
申请号：US15385054
申请日：2016-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Gregory SZEWCZYK , Lisa MANUS , Lyndsay SCHAEFFER-KORBYLO , Andrei POTANIN , Ravi SUBRAMANYAM
CPC classification number: A61K8/27 , A61K8/21 , A61K8/24 , A61K8/44 , A61K8/8176 , A61K8/8182 , A61K2800/58 , A61Q11/00 , A61Q11/02
Abstract: Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and linear polyvinylpyrrolidone and/or sodium tripolyphosphate, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.
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公开(公告)号：US20220192952A1
公开(公告)日：2022-06-23
申请号：US17695100
申请日：2022-03-15
Applicant: Colgate-Palmolive Company
Inventor： Zhigang HAO , Chi-Yuan CHENG , Long PAN , Ravi SUBRAMANYAM
Abstract: The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C22H32Cl2N10][C6H12NO3S]2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.
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公开(公告)号：US20200291047A1
公开(公告)日：2020-09-17
申请号：US16889093
申请日：2020-06-01
Applicant: Colgate-Palmolive Company
Inventor： Viktor DUBOVOY , Long PAN , Ravi SUBRAMANYAM , Tatiana BRINZARI
Abstract: Described herein are complexes comprising a cationic antibacterial agent and a metal salt; oral care compositions comprising same; along with methods of making and using these complexes and compositions.
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公开(公告)号：US20190183765A1
公开(公告)日：2019-06-20
申请号：US16216533
申请日：2018-12-11
Applicant: Colgate-Palmolive Company
Inventor： Long PAN , Donghui WU , Ravi SUBRAMANYAM , Hongwei SHEN , Chi-Yuan CHENG , Tatiana BRINZARI
IPC: A61K8/44 , A61Q11/00 , A61K31/198 , A61K8/21 , A61K33/16 , A61K31/4172
CPC classification number: A61K8/44 , A61K8/19 , A61K8/21 , A61K8/442 , A61K8/445 , A61K8/447 , A61K8/492 , A61K8/4946 , A61K31/198 , A61K31/4172 , A61K33/16 , A61K2800/58 , A61Q11/00 , C07C269/04 , C07C271/06 , C07C279/14
Abstract: Disclosed herein are amino acid carbamate complexes, methods of synthesis thereof, oral care compositions comprising the same, and methods of making and using thereof.
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公开(公告)号：US20190175479A1
公开(公告)日：2019-06-13
申请号：US16213871
申请日：2018-12-07
Applicant: Colgate-Palmolive Company
Inventor： Zhigang HAO , Dennis ZHANG , Donghui WU , Ravi SUBRAMANYAM , Chi-Yuan CHENG , Long PAN , Stanislav JARACZ
Abstract: Disclosed herein are zinc-amino acid-tripolyphosphate complexes, oral care and personal care compositions comprising zinc-amino acid-tripolyphosphate complexes, and methods of making and using the same.
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