公开(公告)号：US20170348207A1

公开(公告)日：2017-12-07

申请号：US15539748

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： Baohua QIAO ,  Long PAN ,  Gregory SZEWCZYK ,  Ravi SUBRAMANYAM

IPC: A61K8/27 ,  A61K8/24 ,  A61Q11/00

CPC classification number: A61K8/27 ,  A61K6/0017 ,  A61K6/0082 ,  A61K8/24 ,  A61K33/42 ,  A61K2800/58 ,  A61Q11/00

Abstract: An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including an inorganic zinc salt, and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.

公开(公告)号：US20170340533A1

公开(公告)日：2017-11-30

申请号：US15539275

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： Baohua QIAO ,  Long PAN ,  Gregory SZEWCZYK ,  Ravi SUBRAMANYAM ,  Shiri NAWROCKI ,  Viktor DUBOVOY

IPC: A61K8/27 ,  A61K8/24 ,  A61Q11/00 ,  A61Q15/00

CPC classification number: A61K8/27 ,  A61K8/24 ,  A61Q11/00 ,  A61Q15/00

Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an organic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the organic zinc salt and long chain polyphosphates being mixed in amounts that provide a phosphorus to zinc mole ratio of 15:1 to about 55:1. Further provided is a method of making this soluble zinc polyphosphate.

公开(公告)号：US20160331651A1

公开(公告)日：2016-11-17

申请号：US15106652

申请日：2013-12-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Jason Nesta ,  Gregory SZEWCZYK ,  Evangelia ARVANITIDOU ,  Alexander MIJALIS

IPC: A61K8/22 ,  A61K8/81 ,  A61K8/24 ,  A61K8/86 ,  A61K8/34 ,  A61K8/37 ,  A61Q11/00 ,  A61K8/60

CPC classification number: A61K8/22 ,  A61K8/24 ,  A61K8/345 ,  A61K8/347 ,  A61K8/37 ,  A61K8/60 ,  A61K8/8147 ,  A61K8/8164 ,  A61K8/86 ,  A61K2800/5422 ,  A61K2800/5424 ,  A61K2800/592 ,  A61K2800/594 ,  A61K2800/596 ,  A61Q11/00 ,  C08K2003/324 ,  C08L33/02 ,  C08L43/02

Abstract: Provided is an oral care composition comprising a phosphate/acrylate co-polymer, a whitening agent and an orally acceptable carrier and methods of using the same.

Abstract translation: 提供了包含磷酸酯/丙烯酸酯共聚物，增白剂和口服可接受的载体的口腔护理组合物及其使用方法。

公开(公告)号：US20160324753A1

公开(公告)日：2016-11-10

申请号：US15107562

申请日：2014-12-10

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Gregory SZEWCZYK ,  Neeta A. PATEL ,  Suzanne JOGUN ,  Shashank POTNIS

IPC: A61K8/73 ,  A61K8/34 ,  A61K8/46 ,  A61K8/21 ,  A61Q11/00 ,  A61K8/02 ,  A61K8/49

CPC classification number: A61K8/731 ,  A61K8/0241 ,  A61K8/0254 ,  A61K8/21 ,  A61K8/345 ,  A61K8/463 ,  A61K8/4993 ,  A61K2800/41 ,  A61K2800/412 ,  A61K2800/43 ,  A61Q11/00

Abstract: Surface staining can be minimized or eliminated by providing an oral care composition comprising a first film comprising a pigment; and optionally a second film; wherein the first film has a dissolution rate in aqueous media that is inversely proportional to its thickness, wherein the first film is in the form of a particle.

Abstract translation: 可以通过提供包含包含颜料的第一膜的口腔护理组合物来最小化或消除表面染色; 和任选的第二膜; 其中所述第一膜在水性介质中具有与其厚度成反比的溶解速率，其中所述第一膜为颗粒形式。

公开(公告)号：US20240197613A1

公开(公告)日：2024-06-20

申请号：US18543423

申请日：2023-12-18

Applicant: Colgate-Palmolive Company

Inventor： Rong DONG ,  Gregory SZEWCZYK ,  Suman CHOPRA

IPC: A61K8/86 ,  A61K8/22 ,  A61K8/24 ,  A61K8/46 ,  A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/86 ,  A61K8/22 ,  A61K8/24 ,  A61K8/463 ,  A61K8/8188 ,  A61Q11/00 ,  A61K2800/28

Abstract: Aspects of the invention are directed to oral care compositions having enhanced peroxide stability. In accordance with some aspects, provided is an oral care composition having a polyol; a whitening agent comprising a peroxide; a thickening agent; and an abrasive system comprising insoluble phosphate salts, wherein the oral care composition contains less than about 5 wt. % of water, and all weight percentages are based on the total weight of the oral care composition.

公开(公告)号：US20230363987A1

公开(公告)日：2023-11-16

申请号：US18212478

申请日：2023-06-21

Applicant: Colgate-Palmolive Company

Inventor： Rong DONG ,  Suman CHOPRA ,  Gregory SZEWCZYK

IPC: A61K8/22 ,  A61K8/21 ,  A61K8/34 ,  A61K8/90 ,  A61Q11/00

CPC classification number: A61K8/22 ,  A61K8/21 ,  A61K8/345 ,  A61K8/90 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/30 ,  A61K2800/48

Abstract: Described herein are oral care compositions comprising: from about 35 wt. % to about 85 wt. % of an anhydrous solvent system (e.g., 35 wt. % to about 75 wt. %); from about 0.02 wt. % to about 30 wt. % of a peroxide solution comprising: from about 0.01 wt. % to about 15 wt. % of hydrogen peroxide, and from about 0.01 wt. % to about 15 wt. % of water; from about 1 wt. % to about 20 wt. % of a thickening system; wherein the oral care composition has a total water content of less than about 30 wt. %; and wherein all weight percentages are based on the total weight of the oral care composition. Methods of making and using these compositions are also described herein.

公开(公告)号：US20170247740A1

公开(公告)日：2017-08-31

申请号：US15509901

申请日：2014-09-24

Applicant: Colgate-Palmolive Company

Inventor： Lyndsay SCHAEFFER-KORBYLO ,  Betty WON ,  Venda Porter MALONEY ,  Gregory SZEWCZYK

IPC: C12Q1/18

Abstract: Provided herein is a method for determining the bioavailability of a metal ion in a composition comprising a source of the metal ion, wherein the metal ion has antimicrobial activity, and wherein the method comprises: a) incubating a sample of the composition with bacterial cells, and b) determining the viability of the bacterial cells after incubation. The method is useful for determining the effect of agents on the bioavailability of metal ions in a composition.

公开(公告)号：US20230057156A1

公开(公告)日：2023-02-23

申请号：US17887237

申请日：2022-08-12

Applicant: Colgate-Palmolive Company

Inventor： Rong DONG ,  Suman CHOPRA ,  Gregory SZEWCZYK

IPC: A61K8/22 ,  A61K8/21 ,  A61K8/90 ,  A61K8/34 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising: from about 35 wt. % to about 85 wt. % of an anhydrous solvent system (e.g., 35 wt. % to about 75 wt. %); from about 0.02 wt. % to about 30 wt. % of a peroxide solution comprising: from about 0.01 wt. % to about 15 wt. % of hydrogen peroxide, and from about 0.01 wt. % to about 15 wt. % of water; from about 1 wt. % to about 20 wt. % of a thickening system; wherein the oral care composition has a total water content of less than about 30 wt. %; and wherein all weight percentages are based on the total weight of the oral care composition. Methods of making and using these compositions are also described herein.

公开(公告)号：US20190167547A1

公开(公告)日：2019-06-06

申请号：US15828787

申请日：2017-12-01

Applicant: Colgate-Palmolive Company

Inventor： Neeta Atul Patel ,  Gregory SZEWCZYK ,  Andre MORGAN ,  Melissa MUIR

IPC: A61K8/27 ,  A61K8/44 ,  A61K8/34 ,  A61K8/81 ,  A61Q11/00

Abstract: Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and a humectant system comprising polyethylene glycol and propylene glycol as structuring humectants, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.

公开(公告)号：US20190091117A1

公开(公告)日：2019-03-28

申请号：US16142738

申请日：2018-09-26

Applicant: Colgate-Palmolive Company

Inventor： Gregory SZEWCZYK ,  Lisa MANUS ,  Lyndsay SCHAEFFER-KORBYLO

IPC: A61K8/24 ,  A61K8/27 ,  A61K8/44 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/25 ,  A61K8/46

Abstract: Disclosed herein are dentifrices comprising a zinc amino acid complex together with soluble phosphate salts. Methods of making and using the dentifrices are also provided.