公开(公告)号：US20220241164A1

公开(公告)日：2022-08-04

申请号：US17250562

申请日：2020-12-17

Applicant: Colgate-Palmolive Company

Inventor： Payal ARORA ,  Harsh Mahendra TRIVEDI ,  Zhigang HAO ,  Paul THOMSON ,  Manish MANDHARE ,  Yu WANG ,  Chi-Yuan CHENG ,  Long PAN

IPC: A61K8/35 ,  A61Q11/00 ,  A61K8/46

Abstract: Described herein are—inter alia—complexes comprising a curcuminoid; and an anionic surfactant. Methods of making and using same are also described.

公开(公告)号：US20210085583A1

公开(公告)日：2021-03-25

申请号：US16955308

申请日：2017-12-19

Applicant: Colgate-Palmolive Company

Inventor： Zhigang HAO ,  Chi-Yuan CHENG ,  Long PAN ,  Ravi SUBRAMANYAM

IPC: A61K8/43 ,  A61K8/46 ,  A61Q11/00 ,  A61K8/02

Abstract: The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C22H32Cl2N10][C6H12NO3S]2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.

公开(公告)号：US20200330343A1

公开(公告)日：2020-10-22

申请号：US16830559

申请日：2020-03-26

Applicant: Colgate-Palmolive Company

Inventor： Zhigang HAO ,  Long PAN ,  Yu WANG

IPC: A61K8/24 ,  A61Q11/00

Abstract: Disclosed herein are improved methods for the synthesis of stannous pyrophosphate, as well as improved methods for the manufacture of oral care compositions comprising stannous pyrophosphate.

公开(公告)号：US20250064697A1

公开(公告)日：2025-02-27

申请号：US18946561

申请日：2024-11-13

Applicant: Colgate-Palmolive Company

Inventor： Payal ARORA ,  Harsh Mahendra TRIVEDI ,  Zhigang HAO ,  Paul THOMSON ,  Manish MANDHARE ,  Yu WANG ,  Chi-Yuan CHENG ,  Long PAN

IPC: A61K8/35 ,  A61K8/46 ,  A61Q11/00

Abstract: Described herein are—inter alia—complexes comprising a curcuminoid; and an anionic surfactant. Methods of making and using same are also described.

公开(公告)号：US20240180799A1

公开(公告)日：2024-06-06

申请号：US18529111

申请日：2023-12-05

Applicant: Colgate-Palmolive Company

Inventor： Tatiana BRINZARI ,  Chi-Yuan CHENG ,  Zhigang HAO ,  Long PAN ,  Cristina CASTRO ,  Viktor DUBOVOY

IPC: A61K8/21 ,  A61K8/19 ,  A61K8/24 ,  A61K8/34 ,  A61K8/365 ,  A61K8/44 ,  A61K8/49 ,  A61Q11/00

CPC classification number: A61K8/21 ,  A61K8/19 ,  A61K8/24 ,  A61K8/347 ,  A61K8/365 ,  A61K8/44 ,  A61K8/498 ,  A61Q11/00 ,  A61K2800/52 ,  A61K2800/522

Abstract: Oral care compositions comprising (i) a stannous ion source and (ii) a chelator or an antioxidant, as well as to methods of using these compositions are disclosed herein.

公开(公告)号：US20240024219A1

公开(公告)日：2024-01-25

申请号：US18256515

申请日：2021-12-09

Applicant: Colgate-Palmolive Company

Inventor： Michelle MIGUELINO ,  Fusong SUN ,  Zhigang HAO

IPC: A61K8/60 ,  A61Q11/00 ,  A61K8/44 ,  A61K8/27

CPC classification number: A61K8/602 ,  A61Q11/00 ,  A61K8/60 ,  A61K8/44 ,  A61K8/27 ,  A61K2800/5922

Abstract: The disclosure provides a natural sweetener system and oral care compositions comprising the same. In one aspect the natural sweetener system comprises a combination of a Rebaudioside A extract and enzymatically glucosylated steviol glycosides extract obtained from Stevia Rebaudiana Bertoni. The natural sweetener system of the disclosure unexpectedly improves the taste of oral care compositions masking the bitterness and metallic notes of Stevia Rebaudiana Bertoni.

公开(公告)号：US20230060978A1

公开(公告)日：2023-03-02

申请号：US17853862

申请日：2022-06-29

Applicant: Colgate-Palmolive Company

Inventor： Tatiana BRINZARI ,  Michael STRANICK ,  Chi-Yuan CHENG ,  Zhigang HAO ,  Iraklis PAPPAS ,  Greggory MARRON ,  Viktor DUBOVOY ,  Long PAN

IPC: A61K8/44 ,  A61K8/02 ,  A61K8/27 ,  A61K8/46 ,  A61Q11/00

Abstract: Described herein are zinc-amino acid-lauryl sulfate complexes and oral care compositions comprising the same; and methods of making and using the same are also described.

公开(公告)号：US20220395441A1

公开(公告)日：2022-12-15

申请号：US17250564

申请日：2020-12-17

Applicant: Colgate-Palmolive Company ,  The University of North Carolina at Chapel Hill

Inventor： Payal Arora ,  Zhigang HAO ,  Paul THOMSON ,  Manish MANDHARE ,  Yu WANG ,  Chi-Yuan CHENG ,  Harsh TRIVEDI ,  Long PAN ,  Silvana BARROS

IPC: A61K8/35 ,  A61Q11/00 ,  A61K8/9794 ,  A61K8/37 ,  A61K8/19 ,  A61K8/25

Abstract: Described herein are methods for improving or maintaining the barrier integrity of gingival tissue comprising administering an oral care composition comprising a curcurninoid, to the oral cavity of a subject in need thereof.

公开(公告)号：US20190185499A1

公开(公告)日：2019-06-20

申请号：US16216466

申请日：2018-12-11

Applicant: Colgate-Palmolive Company

Inventor： Zhigang HAO ,  Chi-Yuan CHENG ,  Long PAN ,  Ravi SUBRAMANYAM

IPC: C07F9/655 ,  A61K8/27 ,  A61K8/21 ,  A61K8/55 ,  A61K8/44 ,  A61K8/365 ,  A61Q11/00

CPC classification number: C07F9/65515 ,  A61K8/19 ,  A61K8/21 ,  A61K8/27 ,  A61K8/365 ,  A61K8/44 ,  A61K8/55 ,  A61K8/676 ,  A61K2800/58 ,  A61Q11/00

Abstract: Disclosed herein are stannous-ascorbyl phosphate and stannic-asorbyl phosphate complexes, oral care compositions stannous-ascorbyl phosphate and stannic-asorbyl phosphate complexes, and methods of making and using the same.