公开(公告)号：US06526317B2

公开(公告)日：2003-02-25

申请号：US09768022

申请日：2001-01-23

申请人： William Hsu ,  Bruce H. KenKnight

发明人： William Hsu ,  Bruce H. KenKnight

IPC分类号： A61N1362

CPC分类号： A61N1/3956 ,  A61N1/3622 ,  A61N1/3987

摘要： A system for defibrillating an atrial region of a heart experiencing a supraventricular arrhytmia. The defibrillation system senses and analyzes both atrial and ventricular cardiac signals of the heart to determine if the heart is experiencing a supraventricular arrhythmia. Upon detecting a supraventricular arrhythmia, the defibrillation system begins delivering a train of atrial pacing pulses to the atria of the heart and a series of ventricular pacing pulses to the ventricles of the heart to synchronize the contractions of the heart with the pacing pulses. The defibrillation system then delivers a defibrillation electrical energy pulse across the atrial region at a predetermined coupling interval time after delivering a final atrial pacing pulse and a final ventricular pacing pulse so that the defibrillation pulse will fall outside the occurrence of a T-wave of the heart, thus reducing the likelihood of inducing ventricular fibrillation.

摘要翻译： 用于去除心脏经心室颤动的心房的心房颤动的系统。 除颤系统感测并分析心脏的心房和心室心脏信号，以确定心脏是否正在经历室上性心律失常。 当检测到室上性心律不齐时，除颤系统开始向心脏的心房传送一系列心房起搏脉冲，并向心脏的心室输送一系列心室起搏脉冲，以使心脏的收缩与起搏脉冲同步。 除颤系统然后在递送最终的心房起搏脉冲和最终的心室起搏脉冲之后以预定的耦合间隔时间在心房区域上递送除颤电能脉冲，使得除颤脉冲将落在外界的T波的出现之外 心脏，从而降低引起心室颤动的可能性。

公开(公告)号：US06526313B2

公开(公告)日：2003-02-25

申请号：US09874892

申请日：2001-06-05

申请人： Robert J. Sweeney ,  William Hsu

发明人： Robert J. Sweeney ,  William Hsu

IPC分类号： A61B50402

CPC分类号： A61B5/7264 ,  A61B5/042 ,  A61B5/04525 ,  A61N1/3962

摘要： A system and method for classifying cardiac depolarization complexes in which waveforms of a depolarization complex are sensed by separate electrodes and correlated with template waveforms of a template depolarization complex. The system is particularly suitable for incorporation into a cardiac rhythm management device such as an implantable cardioverter/defibrillator or pacemaker in order to facilitate arrhythmia prediction and/or prevention.

公开(公告)号：US06405319B1

公开(公告)日：2002-06-11

申请号：US09492886

申请日：2000-01-27

申请人： Nicolas Georg Arnold ,  Peter A. Daley ,  Narendra K. Ghosh ,  William Hsu ,  Michael C. Lai

发明人： Nicolas Georg Arnold ,  Peter A. Daley ,  Narendra K. Ghosh ,  William Hsu ,  Michael C. Lai

IPC分类号： H04L900

CPC分类号： H04L63/18 ,  H04L51/00

摘要： A system for validating network communication, such as e-mail. A person sending information to a previously unverified recipient first enters “Address Book” information about the unverified recipient into the sender's e-mail system. Part of this initial information includes the recipient's e-mail address and a way of communicating with the intended recipient other than by using the e-mail address. For example, regular mail, fax, or other means can be specified. When the sender sends the information to the intended recipient, the recipient is not able to receive the information until an identification code is entered by the intended recipient. The identification code is transferred via the different way of communicating that does not use the intended recipient's e-mail address. For example, the code can be sent via fax. The intended recipient then logs on to the e-mail system and enters their user name and the code. When the recipient logs on for the first time and enters the QAN, the recipient's e-mail account is associated with the sender's entry for that intended user in the sender's private address book. Provision is also made for a representative of the recipient, as opposed to the actual recipient, to perform the logon and receive the information. As part of the logon process, the person logging in is asked to attest that they are the intended recipient or a representative of the intended recipient. The initial logging on of the intended recipient, or the intended recipient's representative, generates an automatic fax to the intended recipient's fax number. This is the same fax number as used to convey the QAN to the intended recipient. This fax upon login acts to defeat any attempt by an outside party to intercept and use the QAN to log on and impersonate the intended recipient. The fax verification upon login is repeated for the first 5 to 10 documents sent by e-mail to recipients who are new users of the system.

公开(公告)号：US06392591B1

公开(公告)日：2002-05-21

申请号：US09813836

申请日：2001-03-22

申请人： William Hsu ,  Oliver Huang ,  Vincent Hung ,  Neil Yang

发明人： William Hsu ,  Oliver Huang ,  Vincent Hung ,  Neil Yang

IPC分类号： H04B7185

CPC分类号： G01S19/37

摘要： A global positioning system comprises a receiving unit, a satellite positioning ASIC (application specific integrated circuit), and a digital interface circuit. The program memory and the micro controller in prior art global positioning system are advantageously replaced by a digital interface circuit. Therefore, the global positioning system of the present invention can achieve the advantages of miniature size, reduced cost and low electrical current consumption.

摘要翻译： 全球定位系统包括接收单元，卫星定位ASIC（专用集成电路）和数字接口电路。 现有技术的全球定位系统中的程序存储器和微控制器有利地被数字接口电路所取代。 因此，本发明的全球定位系统可以实现小尺寸，降低成本和低电流消耗的优点。

公开(公告)号：US06312388B1

公开(公告)日：2001-11-06

申请号：US09267306

申请日：1999-03-12

申请人： Alan F. Marcovecchio ,  William Hsu

发明人： Alan F. Marcovecchio ,  William Hsu

IPC分类号： A61B504

CPC分类号： A61B5/04525

摘要： A method and system for verifying the integrity of normal sinus rhythm (NSR) templates and updating the NSR template after selected time intervals. At selected time intervals after establishing a NSR template, cardiac complexes are sensed and values for one or more cardiac parameters are measured. The values of the cardiac parameters are compared to predetermined value ranges for NSR cardiac complexes. When the values of the cardiac parameters fall within the predetermined value ranges, values for the differences between the values of the cardiac parameters for the cardiac complexes and the values for the cardiac parameters of the NSR cardiac complexes are calculated. When the values of the differences are greater than one or more threshold values, the NSR template is updated as a function of the sensed cardiac complexes.

摘要翻译： 一种用于验证正常窦性心律（NSR）模板的完整性并在选定的时间间隔后更新NSR模板的方法和系统。 在建立NSR模板之后的选定的时间间隔，感测心脏复合物并测量一个或多个心脏参数的值。 将心脏参数的值与NSR心脏复合物的预定值范围进行比较。 当心脏参数的值落在预定值范围内时，计算心脏复合物心脏参数值与NSR心脏复合物心脏参数值之差的值。 当差异的值大于一个或多个阈值时，NSR模板被更新为感测的心脏复合物的函数。

公开(公告)号：US06308095B1

公开(公告)日：2001-10-23

申请号：US09248800

申请日：1999-02-12

申请人： William Hsu ,  Joseph Martin Smith

发明人： William Hsu ,  Joseph Martin Smith

IPC分类号： A61B50464

CPC分类号： A61N1/3622

摘要： The present invention provides a system and a method for discriminating supraventricular tachyarrhythmias from ventricular arrhythmias during a tachycardia episode. First cardiac signals and second cardiac signals are sampled for cardiac complexes. A first feature on the first cardiac signal and a second feature on the second cardiac signal are utilized to determine an average time difference for a plurality of normal sinus rhythm complexes. A time difference between the first feature and the second feature is then determined for each cardiac complex of a tachycardiac rhythm. The cardiac complex is characterized as a ventricular tachycardia complex if the time difference exceeds the average time difference by a predetermined amount. Otherwise, it is classified as VT if its morphology after alignment is different from that during normal sinus rhythm.

摘要翻译： 本发明提供了一种用于在心动过速发作期间区分室上性快速性心律失常与室性心律失常的系统和方法。 对心脏复合物采集第一心脏信号和第二心脏信号。 使用第一心脏信号的第一特征和第二心脏信号上的第二特征来确定多个正常窦性心律复合体的平均时间差。 然后针对心动过速节律的每个心脏复合体确定第一特征和第二特征之间的时间差。 如果时间差超过平均时间差预定量，则心脏复合物被表征为心室心动过速复合物。 否则，如果其对准后的形态与正常窦性心律不同，则分类为VT。

公开(公告)号：US06252830B1

公开(公告)日：2001-06-26

申请号：US09418497

申请日：1999-10-15

申请人： William Hsu

发明人： William Hsu

IPC分类号： G11B2112

CPC分类号： G11B21/12

摘要： A real-time compressing and decompressing apparatus for recording and reproducing multi-soundtrack voice data is disclosed. The apparatus comprises a real-time decompressing module for reproducing digital voice; a pre-module for real-time compressing digital voice; a long-term primary and secondary power control module; a controllable working-frequency adjusting module; a linking module for supplying power; and a digital voice memory module. Therefore, the digital voice is not distorted, the voice data is read directly from computer network and audio input unit and real-time compressed to store in memory. Moreover, the decompression operation is performed simultaneously with the compression operation to real-time playback voice data. The data can be sustained for long time. The present invention provides primary power for main operation and secondary power for memory storage, and uses SDRAM in place of flash memory to reduce cost.

摘要翻译： 公开了一种用于记录和再现多声道语音数据的实时压缩和解压缩装置。 该装置包括用于再现数字语音的实时解压缩模块; 用于实时压缩数字语音的前置模块; 长期的一次和二次电源控制模块; 可控工作频率调整模块; 用于供电的连接模块; 和数字语音存储器模块。 因此，数字语音不会失真，语音数据直接从计算机网络和音频输入单元读取，实时压缩存储在内存中。 此外，与压缩操作同时执行解压缩操作以实时播放语音​​数据。 数据可以持续很长时间。 本发明提供主要操作的主要功率和用于存储器存储的二次电源，并且使用SDRAM代替闪存以降低成本。

公开(公告)号：US06246906B1

公开(公告)日：2001-06-12

申请号：US09044651

申请日：1998-03-19

申请人： William Hsu ,  Bruce H. KenKnight

发明人： William Hsu ,  Bruce H. KenKnight

IPC分类号： A61N1362

CPC分类号： A61N1/3956 ,  A61N1/3622 ,  A61N1/3987

摘要： A system for defibrillating an atrial region of a heart experiencing a supraventricular arrhythmia. The defibrillation system senses and analyzes both atrial and ventricular cardiac signals of the heart to determine if the heart is experiencing a supraventricular arrhythmia. Upon detecting a supraventricular arrhythmia, the defibrillation system begins delivering a train of atrial pacing pulses to the atria of the heart and a series of ventricular pacing pulses to the ventricles of the heart to synchronize the contractions of the heart with the pacing pulses. The defibrillation system then delivers a defibrillation electrical energy pulse across the atrial region at a predetermined coupling interval time after delivering a final atrial pacing pulse and a final ventricular pacing pulse so that the defibrillation pulse will fall outside the occurrence of a T-wave of the heart, thus reducing the likelihood of inducing ventricular fibrillation.

公开(公告)号：US6091990A

公开(公告)日：2000-07-18

申请号：US432694

申请日：1999-11-03

申请人： William Hsu ,  Douglas J. Lang

发明人： William Hsu ,  Douglas J. Lang

IPC分类号： A61N1/37 ,  A61N1/372

CPC分类号： A61N1/37247 ,  G06F19/3406 ,  G06F19/345 ,  A61N1/3702 ,  G06F19/3487

摘要： A medical device system and method of plotting symbols representing complexes of selected arrhythmic events on an interactive display screen, for organizing, displaying and interacting with a patient's recorded arrhythmia episodes. Stored arrhythmic episode are selected from a plurality of arrhythmic episodes, where the stored arrhythmic episode having a plurality of complexes. A similarity value and a dissimilarity value is calculated for each complex of the plurality of complexes of the selected arrhythmic episode with respect to normal sinus rhythm complexes. Symbols representing the arrhythmic complexes are then plotted as a function of the calculated similarity values and the dissimilarity values on an interactive display screen. Additional information relating to the arrhythmic event is elicited through interacting with the symbols displayed on the interactive display screen.

摘要翻译： 一种用于在交互式显示屏幕上绘制表示所选择的心律失常事件的复合体的符号的图形化的医疗装置系统和方法，用于组织，显示和与患者记录的心律失常发作相互作用。 存储的心律失常发作选自多种心律失常发作，其中存储的心律不齐事件具有多个复合物。 对于所选择的心律失常发作的多个复合物相对于正常窦性心律复合物的每个复合物计算相似值和不相似性值。 然后将表示心律不齐复合物的符号作为在交互式显示屏幕上计算的相似度值和不相似性值的函数来绘制。 通过与交互式显示屏幕上显示的符号进行交互，引发与心律失常事件相关的附加信息。

公开(公告)号：US5885221A

公开(公告)日：1999-03-23

申请号：US996355

申请日：1997-12-22

申请人： William Hsu ,  Jay A. Warren ,  Gerrard M. Carlson

发明人： William Hsu ,  Jay A. Warren ,  Gerrard M. Carlson

IPC分类号： A61N1/362 ,  A61B5/0464

CPC分类号： A61N1/3622

摘要： A method and system for discriminating atrial and ventricular signal components from a single heart lead, and for using this information for identifying an arrhythmia condition as being atrial or ventricular in origin. The invention is effective in identifying P waves occurring in complex signal which includes relatively stronger R waves or other ventricular artifacts which mask the P waves. The contribution of the R wave signal to the complex signal is obtained by filtering, time windowing and transfer function estimation, then the R wave estimate is subtracted from the combined signal to leave the P wave. The ratio of P waves to R waves, P-P and R-R intervals, and their ratios to one another and to fixed values can be estimated, and used in a comparison to discriminate between atrial and ventricular arrhythmia, to thereby enable appropriate treatment.

摘要翻译： 用于区分来自单个心脏引线的心房和心室信号分量的方法和系统，以及用于将该信息用于将心律失常状态识别为心房或心室起源的方法和系统。 本发明有效地识别出复杂信号中出现的P波，其中包含相对较强的R波或掩蔽P波的其他心室伪像。 通过滤波，时间窗口和传递函数估计得到R波信号对复信号的贡献，然后将R波估计从组合信号中减去离开P波。 可以估计P波与R波，P-P和R-R间隔的比率以及它们彼此之间的比值和固定值，并用于比较以区分心房和心室心律不齐，从而使得能够进行适当的治疗。