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公开(公告)号:US20220288103A1
公开(公告)日:2022-09-15
申请号:US17271998
申请日:2019-08-28
Applicant: DSM IP ASSETS B.V.
Inventor: Maaike Johanna BRUINS , Sophie FEHLBAUM , Thanh-Van PHAM , Kevin PRUDENCE , Robert STEINERT , Pietro CELI , Gilberto LITTA , Estefania PEREZ CALVO , Wilbert SYBESMA
IPC: A61K31/714 , A61K31/07 , A61K31/525 , A61K31/375 , A61K31/593 , A61K31/122 , A61K31/519 , A61K31/015 , A61K31/51 , A61K31/455 , A61K31/197 , A61K31/4415 , A61K31/4188 , A61K31/202 , A61K31/355 , A61P1/14
Abstract: Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.
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公开(公告)号:US20220000891A1
公开(公告)日:2022-01-06
申请号:US17291481
申请日:2019-11-08
Applicant: DSM IP Assets B.V. , Midori USA, Inc.
Inventor: Britta BLOKKER , Stephane DUVAL , John Michael GEREMIA , Estefania PEREZ CALVO , Nathalie RICHARD , Jerome SCHMEISSER , Nicole SEIFERT , Viviane VERLHAC
IPC: A61K31/702 , A61K9/00 , A61P1/00 , A23K20/163 , A23K50/75 , A23K50/30
Abstract: The present disclosure relates to methods of feeding animals by providing feed additives that modulate the gut microbiome to prevent or treat dysfunctions in a gastrointestinal barrier. The present disclosure further relates to methods of feeding animals by providing feed additives that modulate the gut microbiome to prevent or treat infections.
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公开(公告)号:US20210084934A1
公开(公告)日:2021-03-25
申请号:US17022416
申请日:2020-09-16
Applicant: DSM IP ASSETS B.V.
Abstract: It has been found that administering probiotic Bacillus strains to animals improves vitamin E absorption. Thus, probiotic Bacillus strains can be used when animals are stressed, e.g. during weaning. The present invention relates to a Bacillus strain as a feed additive, which is useful for improving vitamin E absorption in animals.
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公开(公告)号:US20200305465A1
公开(公告)日:2020-10-01
申请号:US16954667
申请日:2018-12-19
Applicant: DSM IP ASSETS B.V.
Inventor: Raffaella AURELI , Leticia CARDOSO BITTENCOURT , Rual LOPEZ-ULIBARRI , Estefania PEREZ CALVO
IPC: A23K20/147 , A23K20/189 , A23K50/75 , A23K10/35
Abstract: The present invention relates to animal feed compositions comprising polypeptides having muramidase activity and uses thereof. Feeding broilers with feed comprising muramidase resulted in a dose-dependent increase of blood carotenoids. Administration of the supplemented feed could likewise increase blood levels of zeaxanthin, lutein, vitamin A, vitamin E and sialic acid.
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公开(公告)号:US20250160366A1
公开(公告)日:2025-05-22
申请号:US18839554
申请日:2023-02-23
Applicant: DSM IP Assets B.V.
Inventor: Elkin AMAYA , Estel CANET-MARTINEZ , Joshua Thomas CLAYPOOL , John Michael GEREMIA , Daniel Beat JOSS , Mohammad-Ali NEJAD-EBRAHIMI , Estefania PEREZ CALVO , Wen REN , Jerome SCHMEISSER , Ghislain SCHYNS , Clement SESTER
IPC: A23K20/163 , A23K10/18 , A23K20/189 , A23K50/30 , A23K50/75
Abstract: The present invention relates to a method for modulating the level of one or more secondary metabolite(s), and a use for modulating the level of one or more secondary metabolite(s) in the gastrointestinal tract of an animal.
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公开(公告)号:US20240293437A1
公开(公告)日:2024-09-05
申请号:US18420540
申请日:2024-01-23
Applicant: DSM IP Assets B.V.
Inventor: Stephane DUVAL , John Michael GEREMIA , Lisa Ann LAPRADE , April WAGUESPACK-LEVY , Estefania PEREZ CALVO , Ghislain SCHYNS , Viviane VERLHAC , Joshua Thomas CLAYPOOL
IPC: A61K31/702 , A23K20/163 , A23K50/30 , A23K50/75
CPC classification number: A61K31/702 , A23K20/163 , A23K50/30 , A23K50/75
Abstract: Methods of feeding animals are disclosed wherein providing feed additives are provided that modulate the gut microbiome to improve the health, nutrition, and growth performance. Methods of modulating the microbial species present in the gastrointestinal tract of an animal are also disclosed. Such modulation includes, for example, modulating the level or function of microbial species.
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公开(公告)号:US20210393658A1
公开(公告)日:2021-12-23
申请号:US17292132
申请日:2019-11-08
Applicant: DSM IP Assets B.V. , Midori USA, Inc.
Inventor: Stephane DUVAL , John Michael GEREMIA , Lisa Ann LAPRADE , April Waguespack LEVY , Estefania PEREZ CALVO , Ghislain SCHYNS , Viviane VERLHAC , Joshua CLAYPOOL
IPC: A61K31/702 , A23K20/163 , A23K50/75 , A23K50/30
Abstract: The present disclosure relates to methods of feeding animals by providing feed additives that modulate the gut microbiome to improve the health, nutrition, and growth performance. The present disclosure further relates to methods of modulating the microbial species present in the gastrointestinal tract of an animal. Such modulation includes, for example, modulating the level or function of microbial species.
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公开(公告)号:US20200337337A1
公开(公告)日:2020-10-29
申请号:US16954660
申请日:2018-12-19
Applicant: DSM IP ASSETS B.V.
Inventor: Raffaella AURELI , Rual LOPEZ-ULIBARRI , Estefania PEREZ CALVO , Leticia CARDOSO BITTENCOURT
IPC: A23K20/189 , C12N9/36 , A23K20/147 , A23K50/75
Abstract: The present invention relates to animal feed compositions comprising polypeptides having muramidase activity and uses thereof. In the Examples it is shown that feeding muramidase to broiler chicken increased apparent ileal digestibility of crude protein and crude fat.
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