公开(公告)号：US20180289624A1

公开(公告)日：2018-10-11

申请号：US15756619

申请日：2016-09-09

Applicant: DSM IP Assets B.V.

Inventor： Markus BECK ,  Andrea BULBARELLO ,  Kevin PRUDENCE ,  Loni SCHWEIKERT ,  Kai URBAN

IPC: A61K9/16 ,  A61K33/26 ,  A23L33/16

Abstract: This invention relates to a process for producing solid formulations. These solid formulations comprise physiologically active inorganic metal salts, which are known for being bad-tasting. These new solid formulation are neutral in taste. Furthermore the present invention relate to these solid formulations as well as to their use in the production of food, feed, nutritional supplement and personal care products.

公开(公告)号：US20220288103A1

公开(公告)日：2022-09-15

申请号：US17271998

申请日：2019-08-28

Applicant: DSM IP ASSETS B.V.

Inventor： Maaike Johanna BRUINS ,  Sophie FEHLBAUM ,  Thanh-Van PHAM ,  Kevin PRUDENCE ,  Robert STEINERT ,  Pietro CELI ,  Gilberto LITTA ,  Estefania PEREZ CALVO ,  Wilbert SYBESMA

IPC: A61K31/714 ,  A61K31/07 ,  A61K31/525 ,  A61K31/375 ,  A61K31/593 ,  A61K31/122 ,  A61K31/519 ,  A61K31/015 ,  A61K31/51 ,  A61K31/455 ,  A61K31/197 ,  A61K31/4415 ,  A61K31/4188 ,  A61K31/202 ,  A61K31/355 ,  A61P1/14

Abstract: Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

公开(公告)号：US20180352842A1

公开(公告)日：2018-12-13

申请号：US15756626

申请日：2016-09-09

Applicant: DSM IP Assets B.V.

Inventor： Markus BECK ,  Andrea BULBARELLO ,  Kevin PRUDENCE ,  Loni SCHWEIKERT ,  Kai URBAN

IPC: A23L33/105 ,  A61K36/185 ,  A61K9/16

CPC classification number: A23L33/105 ,  A23L5/00 ,  A23L27/70 ,  A23L27/84 ,  A23P10/40 ,  A23V2002/00 ,  A61K9/1617 ,  A61K36/185 ,  A61K36/736 ,  A61K2236/00

Abstract: This invention relates to a process for producing solid formulations. These solid formulations comprise therapeutically active or nutritious plant extracts, which are known for being bad-tasting. These new solid formulation are neutral in taste. Furthermore the present invention relate to these solid formulations as well as to their use in the production of food, feed, nutritional supplement and personal care products.

公开(公告)号：US20180133193A1

公开(公告)日：2018-05-17

申请号：US15864974

申请日：2018-01-08

Applicant: DSM IP ASSETS B.V.

Inventor： Kevin PRUDENCE ,  Christoph RIEGGER ,  Wolfgang SCHALCH

IPC: A61K31/352 ,  A23L33/105

CPC classification number: A61K31/352 ,  A23L33/105

Abstract: Use of genistein for the treatment and prevention of dry eye syndrome or LKC and corresponding compositions containing it.