公开(公告)号：US20210145581A1

公开(公告)日：2021-05-20

申请号：US17159668

申请日：2021-01-27

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  James R. Yamada ,  Rodolfo Rodriguez ,  Da-Yu Chang ,  Steven M. Ford

IPC: A61F2/24

Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.

公开(公告)号：US20170143480A1

公开(公告)日：2017-05-25

申请号：US15402998

申请日：2017-01-10

Applicant: Edwards Lifesciences Corporation

Inventor： Rodolfo Rodriguez

IPC: A61F2/24 ,  C23C14/00 ,  C23C14/06 ,  C23C14/02 ,  C23C14/32 ,  C23C14/16

CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2210/0076 ,  C23C14/0021 ,  C23C14/025 ,  C23C14/0641 ,  C23C14/16 ,  C23C14/24 ,  C23C14/325 ,  C23C16/34 ,  C23C16/44 ,  Y10T29/49885 ,  Y10T29/49982

Abstract: An improved heart bioprosthetic device having a metal frame wireform or stent having an outer external surface. The metal frame has a bond layer coating at least a portion of the external surface and a coating layer disposed on at least a portion of the bond layer. The bond layer comprises a metal selected from the group consisting of: chromium, titanium, zirconium, aluminum, platinum, palladium, and niobium. The coating layer is selected from the group consisting of: a metal nitride, a metal oxide, a metal carbide, and combinations thereof. The coating layer may have a thickness of about 10 μm or less and a grain size of about 10 nm to about 15 nm, and may be characterized as polycrystalline with randomly-oriented grains with both cubic and orthorhombic phases. In one embodiment, the bond layer comprises chromium and the coating layer comprises chromium nitride.

公开(公告)号：US12167964B2

公开(公告)日：2024-12-17

申请号：US18069082

申请日：2022-12-20

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  James R. Yamada ,  Rodolfo Rodriguez ,  Da-Yu Chang ,  Steven M. Ford

IPC: A61F2/24

Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.

公开(公告)号：US11554015B2

公开(公告)日：2023-01-17

申请号：US17159668

申请日：2021-01-27

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  James R. Yamada ,  Rodolfo Rodriguez ,  Da-Yu Chang ,  Steven M. Ford

IPC: A61F2/24

Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.

公开(公告)号：US20220008199A1

公开(公告)日：2022-01-13

申请号：US17487232

申请日：2021-09-28

Applicant: Edwards Lifesciences Corporation

Inventor： Derrick Johnson ,  Michael C. Murad ,  Steven M. Ford ,  Rodolfo Rodriguez

IPC: A61F2/24

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein. A dual-wireform support frame including an upper and a lower wireform permits expansion of the valve by one or two valve sizes, for example, with a 2-mm gap between each valve size. The lower wireform has a relatively shallow undulation so that it may stretch apart by a small amount and then prevent further expansion of the valve.

公开(公告)号：US20200069426A1

公开(公告)日：2020-03-05

申请号：US16549957

申请日：2019-08-23

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Maria L. Saravia ,  Adam J. Yestrepsky ,  Derrick Johnson ,  Rodolfo Rodriguez ,  Sai Prasad Uppalapati ,  Louis A. Campbell

IPC: A61F2/24

Abstract: Systems, apparatuses, and methods disclosed herein are provided for medical treatment, including transcatheter medical treatments and/or for treatment of dilated hearts (e.g., dilated left ventricle) or functional mitral valve regurgitation within a human heart. The systems, apparatuses, and methods disclosed herein may include applying one or more heart splints to the patient's heart to apply pressure to the heart to reshape the heart. Anchors disclosed herein may be utilized in plugs for treating openings in a septum between two chambers of a heart, e.g., ventricular septal defects (VSD), atrial septal defects (ASD), and patent foramen ovale (PFO). In addition, the anchors disclosed herein may be utilized to reshape an annulus of a patient's heart valve, including a tricuspid valve of a patient's heart. The anchors disclosed herein may also be utilized to reposition a heart valve leaflet to reduce heart valve leaflet prolapse.

公开(公告)号：US20200000586A1

公开(公告)日：2020-01-02

申请号：US16570797

申请日：2019-09-13

Applicant: Edwards Lifesciences Corporation

Inventor： Bin Tian ,  Rodolfo Rodriguez ,  Louis A. Campbell ,  Steven M. Claessens ,  Carolyn Sue Martinez

IPC: A61F2/24

Abstract: Systems, devices, kits, and methods are described for securing a bioprosthetic heart valve within an anatomical feature of a patient. Kits can comprise a bioprosthetic heart valve, a curable composition, and an applicator configured to deliver the curable composition to a target area. The bioprosthetic heart valve can comprise a support structure and one or more valve leaflets coupled thereto. The support structure can comprise a sewing portion peripheral of the bioprosthetic heart valve. The support structure and the valve leaflets can define a central flow orifice. The curable composition can comprise a pre-polymer composition and an initiator. Methods can comprise positioning the bioprosthetic heart valve within the anatomical feature of a patient, applying the curable composition to one or both of the bioprosthetic heart valve and the anatomical feature, and curing the curable composition for a cure time. The applying can be performed before or after the positioning.