公开(公告)号：US20190212539A1

公开(公告)日：2019-07-11

申请号：US16355958

申请日：2019-03-18

Applicant: FUJIFILM Corporation

Inventor： Yasushi SHIRAISHI

IPC: G02B21/26 ,  G02B21/14 ,  G02B7/28

CPC classification number: G02B21/26 ,  G02B7/28 ,  G02B7/32 ,  G02B21/14 ,  G02B21/24 ,  G02B21/36

Abstract: Before an observation region of an imaging optical system 14 reaches an observation position in the cultivation container 50, a vertical position of the cultivation container 50 at the observation position is precedently detected by an auto-focus displacement sensor. In a case where an objective lens is moved in an optical axis direction on the basis of the position, an error between the precedently detected vertical position of the stage 51 at the observation position and a vertical position of the stage 51 at a time point when the observation region of the imaging optical system 14 is scanned up to the observation position is acquired, and the objective lens is moved in the optical axis direction on the basis of the error.

公开(公告)号：US20160089011A1

公开(公告)日：2016-03-31

申请号：US14869062

申请日：2015-09-29

Applicant: FUJIFILM Corporation

Inventor： Yasushi SHIRAISHI ,  Tatsuya AOYAMA

IPC: A61B1/06 ,  H04N9/07 ,  H04N5/225 ,  A61B1/04 ,  G06T7/00 ,  H04N5/235 ,  H04N5/357 ,  H04N9/04 ,  G06K9/46

CPC classification number: A61B1/0638 ,  A61B1/00009 ,  A61B1/04 ,  A61B1/0684 ,  G06K9/46 ,  G06T7/0012 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/20212 ,  G06T2207/30101 ,  H04N5/2354 ,  H04N9/045 ,  H04N2005/2255

Abstract: An endoscope system includes a light source unit, an image sensor, an image signal obtaining section, a vessel position signal generator, a vessel width signal generator, and a vessel image signal generator. The light source unit generates illumination light. The image sensor captures an image of an object of interest irradiated with the illumination light. The image signal obtaining section obtains an image signal, which represents the object, from the image sensor. The vessel position signal generator generates a vessel position signal, which represents the position of a blood vessel of the object, from the image signal. The vessel width signal generator generates a vessel width signal, which represents the width of the blood vessel, from the image signal. The vessel image signal generator generates a vessel image signal, which represents the blood vessel, from the vessel position signal and the vessel width signal.

Abstract translation: 内窥镜系统包括光源单元，图像传感器，图像信号获取部，容器位置信号发生器，血管宽度信号发生器和血管图像信号发生器。 光源单元产生照明光。 图像传感器捕获用照明光照射的感兴趣对象的图像。 图像信号获取部从图像传感器获取表示对象的图像信号。 容器位置信号发生器根据图像信号产生表示物体的血管位置的血管位置信号。 容器宽度信号发生器根据图像信号产生表示血管宽度的容器宽度信号。 容器图像信号发生器从血管位置信号和血管宽度信号产生代表血管的血管图像信号。

公开(公告)号：US20250027025A1

公开(公告)日：2025-01-23

申请号：US18905220

申请日：2024-10-03

Applicant: FUJIFILM Corporation

Inventor： Yasushi SHIRAISHI

IPC: C12M1/26 ,  C12M1/00 ,  C12M1/34 ,  C12M1/36

Abstract: A cell seeding apparatus of the present disclosure includes a dropping device that drops a liquid droplet of a cell suspension into a cell culture vessel having a measurement electrode and a reference electrode disposed on a bottom surface, an imaging device that is provided in the dropping device and that images the bottom surface to generate an image, and an information processing device that detects positions of the measurement electrode and the reference electrode based on the image and that decides, based on detection information, a dropping position of the liquid droplet at which cells are to be placed on the measurement electrode without placing the cells on the reference electrode.

公开(公告)号：US20240153083A1

公开(公告)日：2024-05-09

申请号：US18534723

申请日：2023-12-11

Applicant: FUJIFILM CORPORATION

Inventor： Yasushi SHIRAISHI

IPC: G06T7/00 ,  H04N23/60

CPC classification number: G06T7/0012 ,  H04N23/64 ,  G06T2207/10056 ,  G06T2207/20216 ,  G06T2207/30024 ,  G06T2207/30168

Abstract: There is provided a cell quality evaluation apparatus that performs a process including estimation processing of estimating a quality of cells in the entirety of a cell-culture container by determining feature quantities from a plurality of images and calculating an average value of the feature quantities; derivation processing of deriving an estimation error of the quality estimated in the estimation processing, based on a variation of the feature quantities in the plurality of images and imaging information related to an area of a plurality of imaging regions; and imaging control processing of causing a imaging apparatus to perform re-imaging on at least one re-imaging region different from the plurality of imaging regions in a case where the estimation error is out of an allowable range.

公开(公告)号：US20200158999A1

公开(公告)日：2020-05-21

申请号：US16749068

申请日：2020-01-22

Applicant: FUJIFILM Corporation

Inventor： Yasushi SHIRAISHI

IPC: G02B21/00 ,  G02B21/34

Abstract: The observation device includes an imaging optical system that includes an imaging lens forming an image of an observation target in a cultivation container, an operating section that performs at least one of a first operation of changing a focal length of the imaging optical system, a second operation of moving the imaging lens in an optical axis direction, or a fourth operation of moving the container in the optical axis direction, a detection section that detects a vertical position of the cultivation container, and an operation controller that controls the operating section based on the vertical position of the cultivation container.

公开(公告)号：US20180113294A1

公开(公告)日：2018-04-26

申请号：US15848895

申请日：2017-12-20

Applicant: FUJIFILM Corporation

Inventor： Yasushi SHIRAISHI

IPC: G02B21/14 ,  G03B15/03 ,  G02B21/00 ,  G02B7/28

CPC classification number: G02B21/14 ,  G02B7/28 ,  G02B21/00 ,  G02B21/0004 ,  G03B15/03

Abstract: A liquid surface in a culture vessel is irradiated with liquid-surface-measurement illumination light, and transmitted light that has passed through the liquid is detected by an imaging unit. A relative positional relationship between a focal plane of an image forming optical system and the culture vessel is changed, a detection signal for each position of the focal plane is obtained, and a liquid surface shape is estimated on the basis of the detection signal for each position of the focal plane. Then, on the basis of the estimated liquid surface shape, adjustment information for adjusting the optical characteristics of an adjustment optical system for adjusting refraction of light due to the liquid surface shape is acquired. After the optical characteristics of the adjustment optical system have been adjusted on the basis of the adjustment information, an image of a specimen is captured by irradiating the culture vessel with phase-contrast-measurement illumination light.

公开(公告)号：US20160183774A1

公开(公告)日：2016-06-30

申请号：US15063776

申请日：2016-03-08

Applicant: FUJIFILM Corporation

Inventor： Yasushi SHIRAISHI

IPC: A61B1/04 ,  A61B1/00 ,  A61B5/145 ,  A61B1/06 ,  A61B5/1459 ,  A61B5/1455

Abstract: There are provided an endoscope system, a processor device, an operation method, and a distance measurement device for accurately measuring the observation distance even if a colorant or residues are present in a subject. An endoscope system 10 includes a light source device 14, an endoscope 12, and an observation distance measurement unit 63. The light source device 14 emits signal light, which has a wavelength band absorbed by hemoglobin contained in the subject, to the subject. The endoscope 12 has an image sensor 48 that images the subject with reflected light of the signal light and outputs an image signal. The observation distance measurement unit 63 measures the observation distance based on the image signal.

Abstract translation: 即使在被检体中存在着色剂或残留物，也可以提供用于精确地测量观察距离的内窥镜系统，处理器装置，操作方法和距离测量装置。 内窥镜系统10包括光源装置14，内窥镜12和观察距离测量单元63.光源装置14将具有被检体中所含的血红蛋白吸收的波长带的信号光发射到被检体。 内窥镜12具有图像传感器48，其以信号光的反射光对被检体进行成像，并输出图像信号。 观察距离测量单元63基于图像信号测量观察距离。