公开(公告)号：US20150151141A1

公开(公告)日：2015-06-04

申请号：US14406125

申请日：2013-06-04

Applicant: Bastien Arnal ,  Mathieu Pernot ,  Mickaël Tanter ,  Mathias Fink

Inventor： Bastien Arnal ,  Mathieu Pernot ,  Mickaël Tanter ,  Mathias Fink

IPC: A61N7/00 ,  G10K15/00

Abstract: Device for focusing pulses comprising at least emitting means comprising a network of transducers, these emitting means being adapted to make the network of transducers emit, into a reflective cavity, at least one wave focused onto at least one target point of a target medium. The reflective cavity comprises a multi-scattering medium adapted to cause multiple scattering of said wave.

Abstract translation: 用于聚焦脉冲的装置至少包括包括换能器网络的发射装置，这些发射装置适于使得换能器网络发射到反射腔中，聚焦在目标介质的至少一个目标点上的至少一个波。 反射腔包括适于引起所述波的多次散射的多散射介质。

公开(公告)号：US20080276709A1

公开(公告)日：2008-11-13

申请号：US12092406

申请日：2007-10-25

Applicant: Jeremy Bercoff ,  Claude Cohen-Bacrie ,  Mathieu Pernot ,  David Savery

Inventor： Jeremy Bercoff ,  Claude Cohen-Bacrie ,  Mathieu Pernot ,  David Savery

IPC: G01N29/00

CPC classification number: G10K11/30

Abstract: The present invention relates to a method for generating mechanical waves within a viscoelastic medium (11) comprising a step of generating an acoustic radiation force (15) within the viscoelastic medium (11) by application of acoustic waves focussed on an interface (13) delimiting two zones (11, 14) having distinct acoustic properties.

Abstract translation: 技术领域本发明涉及一种用于在粘弹性介质（11）内产生机械波的方法，包括通过施加聚焦在界面（13）上的声波来在粘弹性介质（11）内产生声辐射力（15）的步骤 具有不同声学特性的两个区域（11,14）。

公开(公告)号：US09168021B2

公开(公告)日：2015-10-27

申请号：US12478514

申请日：2009-06-04

Applicant: Mathieu Pernot ,  Mickaël Tanter ,  Mathieu Couade ,  Mathias Fink

Inventor： Mathieu Pernot ,  Mickaël Tanter ,  Mathieu Couade ,  Mathias Fink

IPC: A61B8/00 ,  A61B8/08 ,  G01N29/11 ,  G01S7/52

CPC classification number: A61B8/08 ,  A61B8/0883 ,  A61B8/485 ,  G01N29/11 ,  G01N2291/02827 ,  G01N2291/0422 ,  G01N2291/044 ,  G01S7/52036 ,  G01S7/52042

Abstract: A Method for measuring heart contractility of a patient, in which a mechanical shear wave is propagated through the heart and observation of the propagation leads to determine a shear wave propagation parameter representative of the elasticity of the heart is disclosed. The value of the propagation parameter at the end of a systole is sampled, which leads to a parameter representative of the end systolic elastance.

Abstract translation: 公开了一种用于测量患者的心脏收缩力的方法，其中机械剪切波通过心脏传播并观察传播，导致确定代表心脏弹性的剪切波传播参数。 收缩收缩末期的传播参数的值被采样，这导致代表收缩末期弹性的参数。

公开(公告)号：US08155725B2

公开(公告)日：2012-04-10

申请号：US12282625

申请日：2008-02-20

Applicant: Mathieu Pernot ,  Mathias Fink ,  Mickaël Tanter ,  Gabriel Montaldo ,  Jean-Francois Aubry ,  Ralph Sinkus

Inventor： Mathieu Pernot ,  Mathias Fink ,  Mickaël Tanter ,  Gabriel Montaldo ,  Jean-Francois Aubry ,  Ralph Sinkus

IPC: A61B5/05

CPC classification number: G01S7/52049 ,  A61B8/0808 ,  A61N7/02 ,  A61N2007/0078 ,  A61N2007/0095 ,  G01S15/8909

Abstract: The invention concerns a method for optimizing the focusing of waves in a zone of interest of a medium, with the waves being emitted by a network of sources to the medium through an aberration-inducing element that introduces an initially indeterminate phase shift. The method according to the invention proposes to use M−1 successive modifications of the emitted wave, each giving rise to a perturbation. According to the invention, the M perturbations are measured in the zone of interest at each modification of the phase and/or amplitude distributions, and these measurements are used to deduce optimal focusing characteristics to maximize the perturbation induced in the zone of interest.

Abstract translation: 本发明涉及一种用于优化介质感兴趣区域中的波的聚焦的方法，其中波被源网络通过引入初始不确定相移的像差诱导元件发射到介质。 根据本发明的方法提出使用发射波的M-1个连续修改，每个引起扰动。 根据本发明，在相位和/或幅度分布的每个修改时，在感兴趣的区域中测量M扰动，并且这些测量用于推导最佳聚焦特性，以使感兴趣区域中诱导的扰动最大化。

公开(公告)号：US20110028838A1

公开(公告)日：2011-02-03

申请号：US12533546

申请日：2009-07-31

Applicant: Mathieu Pernot ,  Mickael Tanter ,  Mathieu Couade ,  Jean-Luc Gennisson ,  Mathias Fink

Inventor： Mathieu Pernot ,  Mickael Tanter ,  Mathieu Couade ,  Jean-Luc Gennisson ,  Mathias Fink

IPC: A61B8/00 ,  G01N29/04

CPC classification number: A61B5/021 ,  A61B5/0048 ,  A61B5/015 ,  A61B5/02007 ,  A61B8/08 ,  A61B8/485 ,  A61B18/0206 ,  A61B18/18 ,  G01N29/0672 ,  G01N2291/02475 ,  G01N2291/02491 ,  G01N2291/02827 ,  G01N2291/0422 ,  G01N2291/044 ,  G01N2291/106

Abstract: Method for measuring a physical parameter in soft tissues of a mammal, in which a mechanical shear wave is propagated through the soft tissues and observation of the propagation leads to determine values of a shear wave propagation parameter. The physical parameter is computed on the basis of these values.

Abstract translation: 用于测量哺乳动物的软组织中的物理参数的方法，其中机械剪切波通过软组织传播并观察传播导致确定剪切波传播参数的值。 基于这些值计算物理参数。

公开(公告)号：US20100312116A1

公开(公告)日：2010-12-09

申请号：US12478514

申请日：2009-06-04

Applicant: Mathieu Pernot ,  Mickaël Tanter ,  Mathieu Couade ,  Mathias Fink

Inventor： Mathieu Pernot ,  Mickaël Tanter ,  Mathieu Couade ,  Mathias Fink

IPC: A61B8/00

CPC classification number: A61B8/08 ,  A61B8/0883 ,  A61B8/485 ,  G01N29/11 ,  G01N2291/02827 ,  G01N2291/0422 ,  G01N2291/044 ,  G01S7/52036 ,  G01S7/52042

Abstract: A Method for measuring heart contractility of a patient, in which a mechanical shear wave is propagated through the heart and observation of the propagation leads to determine a shear wave propagation parameter representative of the elasticity of the heart is disclosed. The value of the propagation parameter at the end of a systole is sampled, which leads to a parameter representative of the end systolic elastance.

Abstract translation: 公开了一种用于测量患者的心脏收缩力的方法，其中机械剪切波通过心脏传播并观察传播，导致确定代表心脏弹性的剪切波传播参数。 收缩收缩末期的传播参数的值被采样，这导致代表收缩末期弹性的参数。