Modified bio-related substance, process for producing the same, and intermediate
    11.
    发明授权
    Modified bio-related substance, process for producing the same, and intermediate 有权
    改性生物相关物质,其生产方法和中间体

    公开(公告)号:US08034981B2

    公开(公告)日:2011-10-11

    申请号:US12942554

    申请日:2010-11-09

    IPC分类号: C07D249/18

    摘要: A modified bio-related substance, wherein at least one poly(alkylene glycol)oxy group represented by the following formula (1) is combined in a molecule: wherein R is a hydrocarbon group having 1 to 24 carbon atoms, OA1 and OA2 are each an oxyalkylene group having 2 to 4 carbon atoms, the groups represented by R are the same or different from each other in one molecule, and the groups represented by OA2 are the same or different from each other in one molecule, n and m are each average number of moles of the oxyalkylene group added, n represents 0 to 1000, and m represents 10 to 1000.

    摘要翻译: 一种改性的生物相关物质,其中至少一种由下式(1)表示的聚(亚烷基二醇)氧基在分子中组合:其中R是具有1至24个碳原子的烃基,OA1和OA2各自 具有2至4个碳原子的氧化烯基,由一个分子中由R表示的基团彼此相同或不同,并且由OA2表示的基团在一个分子中彼此相同或不同,n和m各自为 氧化烯基的平均加成摩尔数,n表示0〜1000,m表示10〜1000。

    SLIDING COMPONENT
    12.
    发明申请
    SLIDING COMPONENT 有权
    滑动组件

    公开(公告)号:US20110215531A1

    公开(公告)日:2011-09-08

    申请号:US12876516

    申请日:2010-09-07

    IPC分类号: F16J15/34

    CPC分类号: F16J15/34 F16J15/3412

    摘要: An aspect of the invention provides a sliding component in which a phase made of liquid and a phase made of gas, which are formed in a sliding portion, are stabilized. A sliding component constitutes one of two sliding components that rotate relatively, and planar end faces of the two sliding component slide on each other. In the sliding component, a plurality of dimples is arrayed in a sliding surface such that, in a phase made of liquid and a phase made of gas, the phase made of the gas is positioned when the two components rotate relatively. The phase made of the liquid and the phase made of the gas are formed so as to revolve about rotation centers of sliding portions of the two components.

    摘要翻译: 本发明的一个方面提供了一种滑动部件,其中形成在滑动部分中的由液体制成的相和由气体制成的相位稳定。 滑动部件构成相对旋转的两个滑动部件中的一个,两个滑动部件的平面端面彼此滑动。 在滑动部件中,多个凹坑排列在滑动表面中,使得在由液体制成的相和由气体制成的相中,当两个部件相对旋转时,由气体制成的相位定位。 由液体制成的相和由气体制成的相形成为围绕两个部件的滑动部分的旋转中心旋转。

    ORTHOGONALITY COMPENSATING DEVICE, RADIO RECEIVING DEVICE, ORTHOGONALITY COMPENSATING METHOD, AND NON-TRANSITORY COMPUTER READABLE MEDIUM
    15.
    发明申请
    ORTHOGONALITY COMPENSATING DEVICE, RADIO RECEIVING DEVICE, ORTHOGONALITY COMPENSATING METHOD, AND NON-TRANSITORY COMPUTER READABLE MEDIUM 审中-公开
    正交校正装置,无线电接收装置,正交校正方法和非终端计算机可读介质

    公开(公告)号:US20100297973A1

    公开(公告)日:2010-11-25

    申请号:US12766572

    申请日:2010-04-23

    IPC分类号: H04B1/10

    摘要: Provided is an orthogonality compensating device that compensates for orthogonality between a real signal and an imaginary signal of complex digital intermediate frequency signals, the orthogonality compensating device including: a first processing unit that outputs a first signal obtained by calculating one of the real signal and the imaginary signal by using a first coefficient and a second coefficient; and a coefficient specifying unit that specifies the first coefficient such that the first signal has the same amplitude as the other of the real signal and the imaginary signal, and specifies the second coefficient such that the first signal is orthogonal to the other of the real signal and the imaginary signal, by using the first signal and the other of the real signal and the imaginary signal.

    摘要翻译: 提供了一种补偿复数数字中频信号的实信号和虚信号之间的正交性的正交性补偿装置,正交性补偿装置包括:第一处理单元,输出通过计算实数信号和 虚信号通过使用第一系数和第二系数; 以及系数指定单元,其指定第一系数,使得第一信号具有与实信号和虚信号中的另一个相同的幅度,并且指定第二系数,使得第一信号与实信号中的另一个正交 和虚信号,通过使用第一信号和另一个实信号和虚信号。

    COMBINATION OF ANTI-ANGIOGENIC SUBSTANCE AND ANTI-TUMOR PLATINUM COMPLEX
    16.
    发明申请
    COMBINATION OF ANTI-ANGIOGENIC SUBSTANCE AND ANTI-TUMOR PLATINUM COMPLEX 有权
    抗生物物质与抗肿瘤白蛋白复合物的组合

    公开(公告)号:US20100239688A1

    公开(公告)日:2010-09-23

    申请号:US12741682

    申请日:2008-11-07

    申请人: Yuji Yamamoto

    发明人: Yuji Yamamoto

    IPC分类号: A61K31/47 A61K33/24 A61P35/00

    CPC分类号: C07D215/48

    摘要: The problems of the present invention are to find a pharmaceutical composition and a method for treating cancer that exhibit excellent anti-tumor effect. Excellent anti-tumor effect is achieved when 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide or an analogous compound thereof, a pharmacologically acceptable salt thereof or a solvate thereof is used in combination with an anti-tumor platinum complex.

    摘要翻译: 本发明的问题是找到表现出优异的抗肿瘤效果的药物组合物和治疗癌症的方法。 当4-(3-氯-4-(环丙基氨基羰基)氨基苯氧基)-7-甲氧基-6-喹啉甲酰胺或其类似化合物,其药理学上可接受的盐或其溶剂化物与4- 抗肿瘤铂复合物。

    Recording or playback apparatus and musical piece detecting apparatus
    18.
    发明授权
    Recording or playback apparatus and musical piece detecting apparatus 有权
    记录或播放装置和乐曲检测装置

    公开(公告)号:US07745714B2

    公开(公告)日:2010-06-29

    申请号:US12053647

    申请日:2008-03-24

    IPC分类号: G10H1/00

    摘要: Provided is a recording or playback apparatus capable of separating a musical piece from an audio including the musical piece and a speech through a simple arithmetic process. A cut point detector detects, as a cut point, a time point at which an audio signal level or an amount of change in the audio signal level is not lower than a predetermined value. A frequency characteristic amount calculator calculates a characteristic amount in a frequency area of the audio signal only at each cut point and in its proximity. A cut point judging unit judges an attribute of the cut point on a basis of the calculated characteristic amount of the frequency. A music section detector detects a start and end points of each music section on a basis of the attribute and an interval between sampling points.

    摘要翻译: 提供了一种能够通过简单的算术处理将音乐作品与包括音乐作品的音频和语音分离的记录或重放装置。 切点检测器检测音频信号电平或音频信号电平的变化量不低于预定值的时间点作为切点。 频率特征量计算器仅在每个切割点和其接近处计算音频信号的频率区域中的特征量。 切点判定部基于计算出的频率特征量来判断切断点的属性。 音乐部分检测器基于属性和采样点之间的间隔检测每个音乐部分的开始和结束点。

    COMPOSITION FOR TREATMENT OF UNDIFFERENTIATED GASTRIC CANCER
    20.
    发明申请
    COMPOSITION FOR TREATMENT OF UNDIFFERENTIATED GASTRIC CANCER 有权
    用于治疗不良胃肠癌的组合物

    公开(公告)号:US20100048620A1

    公开(公告)日:2010-02-25

    申请号:US12524754

    申请日:2008-01-28

    申请人: Yuji Yamamoto

    发明人: Yuji Yamamoto

    CPC分类号: C07D215/22

    摘要: Disclosed are: a therapeutic agent, a kit and a treatment method for undifferentiated gastric cancer; and a pharmaceutical composition, a kit and a treatment method which are more effective on a living organism having at least one cell selected from the group consisting of a cell overexpressing FGFR2 and a cell expressing a mutant FGFR2. A combination of a FGFR2 inhibitor and a therapeutic substance for gastric cancer is more effective on undifferentiated gastric cancer. The combination of a FGFR2 inhibitor and a therapeutic substance for gastric cancer is more effective on a living organism having at least one cell selected from the group consisting of a cell overexpressing FGFR2 and a cell expressing a mutant FGFR2.

    摘要翻译: 公开的是:未分化胃癌的治疗剂,试剂盒和治疗方法; 以及对具有至少一种选自由过表达FGFR2的细胞和表达突变型FGFR2的细胞组成的组的生物体有效的药物组合物,试剂盒和治疗方法。 FGFR2抑制剂与胃癌治疗物质的组合在未分化胃癌中更为有效。 用于胃癌的FGFR2抑制剂和治疗物质的组合对于具有至少一种选自由过表达FGFR2的细胞和表达突变型FGFR2的细胞组成的组的生物体来说更有效。