公开(公告)号：US09783567B2

公开(公告)日：2017-10-10

申请号：US15046399

申请日：2016-02-17

Applicant: Gilead Sciences, Inc.

Inventor： Richard Hung Chiu Yu ,  Brandon Heath Brown ,  Richard P. Polniaszek ,  Benjamin R. Graetz ,  Keiko Sujino ,  Duong Tran ,  Alan Scott Triman ,  Kenneth M. Kent ,  Steven Pfeiffer

IPC: C07H19/00 ,  C07H19/22 ,  C07H19/20 ,  C07H19/02 ,  C07H19/04 ,  C07H19/173 ,  C07D473/34 ,  C07F9/40 ,  C07F9/44 ,  C07F9/6561 ,  C07H19/16 ,  C07H23/00

CPC classification number: C07H19/20 ,  C07D473/34 ,  C07F9/4075 ,  C07F9/4449 ,  C07F9/65616 ,  C07H19/02 ,  C07H19/04 ,  C07H19/16 ,  C07H19/173 ,  C07H23/00

Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.

公开(公告)号：US20160340379A1

公开(公告)日：2016-11-24

申请号：US15046399

申请日：2016-02-17

Applicant: Gilead Sciences, Inc.

Inventor： RICHARD HUNG CHIU YU ,  Brandon Heath Brown ,  Richard P. Polniaszek ,  Benjamin R. Graetz ,  Keiko Sujino ,  Duong Tran ,  Alan Scott Triman ,  Kenneth M. Kent ,  Steven Pfeiffer

IPC: C07H19/20

CPC classification number: C07H19/20 ,  C07D473/34 ,  C07F9/4075 ,  C07F9/4449 ,  C07F9/65616 ,  C07H19/02 ,  C07H19/04 ,  C07H19/16 ,  C07H19/173 ,  C07H23/00

Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.

公开(公告)号：US09381206B2

公开(公告)日：2016-07-05

申请号：US14585011

申请日：2014-12-29

Applicant: Gilead Sciences, Inc.

Inventor： Benjamin R. Graetz ,  Richard Polniaszek

IPC: A61K31/7076 ,  A61K45/06 ,  C07H19/20 ,  A61K9/20

CPC classification number: C07H19/20 ,  A61K9/20 ,  A61K9/2018 ,  A61K31/675 ,  A61K31/7076 ,  A61K45/06 ,  A61K2300/00

Abstract: The invention is related to salts of anti-viral compounds, compositions containing such salts, and therapeutic methods that include the administration of such salts, as well as to process and intermediates useful for preparing such salts.

Abstract translation: 本发明涉及抗病毒化合物的盐，含有这些盐的组合物，以及包括施用这些盐的治疗方法以及可用于制备这些盐的方法和中间体。