公开(公告)号：US20240368647A1

公开(公告)日：2024-11-07

申请号：US18772512

申请日：2024-07-15

Applicant: GIVAUDAN SA

Inventor： Eric EICHHORN ,  Boris SCHILLING ,  Denis WAHLER ,  Laurent FOURAGE ,  Esther LOCHER

IPC: C12P17/04 ,  C07D307/92 ,  C12N9/90

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US20230212624A1

公开(公告)日：2023-07-06

申请号：US18018360

申请日：2021-07-29

Applicant: Givaudan SA

Inventor： Jean-Pierre BARRAS ,  Sylvie MOREL ,  Eric EICHHORN

IPC: C12P17/04 ,  C12N9/90

CPC classification number: C12P17/04 ,  C12N9/90 ,  C12Y504/99017

Abstract: A method for purifying a crude flavor or perfumery or cosmetic ingredient or intermediate, for example crude (−)-Ambrox, comprising a number of washing steps, the products of said method, and uses of said product.

公开(公告)号：US20230175027A1

公开(公告)日：2023-06-08

申请号：US17995512

申请日：2021-04-14

Applicant: Givaudan SA

Inventor： Eric EICHHORN ,  Felix FLACHSMANN ,  Andreas GOEKE

IPC: C12P17/18 ,  C12N9/90 ,  C11B9/00

CPC classification number: C12P17/181 ,  C12N9/90 ,  C12Y504/99017 ,  C11B9/008

Abstract: An enzyme-mediated method for the production of Amberketal and Amberketal homologues, the products of said method, and uses of said products.

公开(公告)号：US20200040369A1

公开(公告)日：2020-02-06

申请号：US16598317

申请日：2019-10-10

Applicant: Givaudan SA

Inventor： Eric EICHHORN ,  Boris SCHILLING ,  Denis WAHLER ,  Laurent FOURAGE ,  Esther LOCHER

IPC: C12P17/04 ,  C12N9/90 ,  C07D307/92

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US20240059636A1

公开(公告)日：2024-02-22

申请号：US18269127

申请日：2021-12-20

Applicant: Givaudan SA

Inventor： Fridtjof SCHRÖDER ,  Eric EICHHORN

IPC: C07C29/147 ,  C07C51/08 ,  C07C231/06 ,  C07C51/09 ,  C07C29/09 ,  C07C233/09 ,  B01J31/24 ,  B01J31/20

CPC classification number: C07C29/147 ,  C07C51/08 ,  C07C231/065 ,  C07C51/09 ,  C07C29/09 ,  C07C233/09 ,  B01J31/2409 ,  B01J31/20 ,  B01J2231/40 ,  B01J2531/821

Abstract: There is provided a method for preparing homofarnesol (1), the method comprising the steps of:



a) providing homofarnesylnitrile (2);
b) reacting homofarnesylnitrile (2) to homofarnesic acid (3); and
c) reacting homofarnesic acid (3) to homofarnesol (1),

wherein the configuration of the double bonds in the compounds 1, 2 and 3 is preserved.

公开(公告)号：US20230220431A1

公开(公告)日：2023-07-13

申请号：US17900590

申请日：2022-08-31

Applicant: Givaudan SA

Inventor： Eric EICHHORN ,  Boris SCHILLING ,  Denis WAHLER ,  Laurent FOURAGE ,  Esther LOCHER

IPC: C12P17/04 ,  C07D307/92 ,  C12N9/90

CPC classification number: C12P17/04 ,  C07D307/92 ,  C12N9/90

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US20220177935A1

公开(公告)日：2022-06-09

申请号：US17680840

申请日：2022-02-25

Applicant: Givaudan SA

Inventor： Ghislain SANHAJI ,  Alix ROUSSEAUX ,  Sandrine NOEL ,  Eric EICHHORN

IPC: C12P17/04 ,  C07D307/92 ,  A61Q13/00

Abstract: A solid form of (−)-Ambrox formed by a bioconversion process.

公开(公告)号：US20220127650A1

公开(公告)日：2022-04-28

申请号：US17427171

申请日：2020-02-26

Applicant: GIVAUDAN SA

Inventor： Felix FLACHSMANN ,  Eric EICHHORN

IPC: C12P7/62

Abstract: A method for making 2-oxygenated decalins form isoprenoids catalysed with a squalene-hopene cyclase (SHC). A fragrance composition comprising (2S*,4aS*,8aR*)-5,5,8a-trimethyldecahydronaphthalen-2-yl acetate.

公开(公告)号：US20210040521A1

公开(公告)日：2021-02-11

申请号：US17070385

申请日：2020-10-14

Applicant: Givaudan SA

Inventor： Ghislain SANHAJI ,  Alix ROUSSEAUX ,  Sandrine NOEL ,  Eric EICHHORN

IPC: C12P17/04 ,  C07D307/92 ,  A61Q13/00

Abstract: A solid form of (−)-Ambrox formed by a bioconversion process.

公开(公告)号：US20190136275A1

公开(公告)日：2019-05-09

申请号：US16095444

申请日：2017-04-20

Applicant: GIVAUDAN SA

Inventor： Ghislain SANHAJI ,  Alix ROUSSEAUX ,  Sandrine NOEL ,  Eric EICHHORN

IPC: C12P17/04 ,  A61Q13/00 ,  C07D307/92

Abstract: A solid form of (−)-Ambrox formed by a bioconversion process.