公开(公告)号：US10940154B2

公开(公告)日：2021-03-09

申请号：US16408718

申请日：2019-05-10

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Jae U. Jeong ,  Deepak Bandyopadhyay ,  Patrick M. Eidam ,  Philip Anthony Harris ,  Jianxing Kang ,  Bryan Wayne King ,  Ami Lakdawala Shah ,  Lara Kathryn Leister ,  Attiq Rahman ,  Joshi M. Ramanjulu ,  Clark A. Sehon ,  Robert Singhaus, Jr. ,  Daohua Zhang

IPC: A61K31/553 ,  A61K31/55 ,  C07D413/14 ,  C07D403/14 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D487/04 ,  C07D267/14 ,  C07D498/04 ,  C07D281/10 ,  A61K31/551 ,  C07D403/12 ,  C07D223/08

Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.

公开(公告)号：US10933070B2

公开(公告)日：2021-03-02

申请号：US16299254

申请日：2019-03-12

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Jae U. Jeong ,  Deepak Bandyopadhyay ,  Patrick M. Eidam ,  Philip Anthony Harris ,  Jianxing Kang ,  Bryan Wayne King ,  Ami Lakdawala Shah ,  Lara Kathryn Leister ,  Attiq Rahman ,  Joshi M. Ramanjulu ,  Clark A. Sehon ,  Robert Singhaus, Jr. ,  Daohua Zhang

IPC: A61K31/55 ,  A61K31/551 ,  A61K31/553 ,  C07D413/14 ,  C07D403/14 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D487/04 ,  C07D267/14 ,  C07D498/04 ,  C07D281/10 ,  C07D403/12 ,  C07D223/08

Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.