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公开(公告)号：US10940154B2
公开(公告)日：2021-03-09
申请号：US16408718
申请日：2019-05-10
发明人： Jae U. Jeong , Deepak Bandyopadhyay , Patrick M. Eidam , Philip Anthony Harris , Jianxing Kang , Bryan Wayne King , Ami Lakdawala Shah , Lara Kathryn Leister , Attiq Rahman , Joshi M. Ramanjulu , Clark A. Sehon , Robert Singhaus, Jr. , Daohua Zhang
IPC分类号： A61K31/553 , A61K31/55 , C07D413/14 , C07D403/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D487/04 , C07D267/14 , C07D498/04 , C07D281/10 , A61K31/551 , C07D403/12 , C07D223/08
摘要： Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
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公开(公告)号：US10933070B2
公开(公告)日：2021-03-02
申请号：US16299254
申请日：2019-03-12
发明人： Jae U. Jeong , Deepak Bandyopadhyay , Patrick M. Eidam , Philip Anthony Harris , Jianxing Kang , Bryan Wayne King , Ami Lakdawala Shah , Lara Kathryn Leister , Attiq Rahman , Joshi M. Ramanjulu , Clark A. Sehon , Robert Singhaus, Jr. , Daohua Zhang
IPC分类号： A61K31/55 , A61K31/551 , A61K31/553 , C07D413/14 , C07D403/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D487/04 , C07D267/14 , C07D498/04 , C07D281/10 , C07D403/12 , C07D223/08
摘要： Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
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公开(公告)号：US20230120185A1
公开(公告)日：2023-04-20
申请号：US17935791
申请日：2022-09-27
发明人： Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC分类号： C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , A61K31/415 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D403/06 , C07D409/06 , C07D413/04
摘要： Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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公开(公告)号：US10590085B2
公开(公告)日：2020-03-17
申请号：US15575235
申请日：2016-05-19
发明人： Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Claude-Marie Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC分类号： A61K31/415 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , C07D403/06 , C07D409/06 , C07D413/04
摘要： Disclosed are compounds having the formula (I): wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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公开(公告)号：US10292987B2
公开(公告)日：2019-05-21
申请号：US15459141
申请日：2017-03-15
发明人： Jae U. Jeong , Deepak Bandyopadhyay , Patrick M. Eidam , Philip Anthony Harris , Jianxing Kang , Bryan Wayne King , Ami Lakdawala Shah , Lara Kathryn Leister , Attiq Rahman , Joshi M. Ramanjulu , Clark A. Sehon , Robert Singhaus, Jr. , Daohua Zhang
IPC分类号： A61K31/553 , C07D267/14 , C07D403/12 , C07D413/14 , C07D403/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D487/04 , C07D498/04 , C07D281/10 , A61K31/55 , C07D223/08
摘要： Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
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公开(公告)号：US20190201413A1
公开(公告)日：2019-07-04
申请号：US16299254
申请日：2019-03-12
发明人： Jae U. JEONG , Deepak Bandyopadhyay , Patrick M. Eidam , Philip Anthony Harris , Jianxing Kang , Bryan Wayne King , Ami Lakdawala Shah , Lara Kathryn Leister , Attiq Rahman , Joshi M. Ramanjulu , Clark A. Sehon , Robert Singhaus, JR. , Daohua Zhang
IPC分类号： A61K31/553 , A61K31/55 , C07D403/12 , C07D223/08 , C07D281/10 , C07D498/04 , C07D413/14 , C07D487/04 , C07D417/12 , C07D413/12 , C07D409/12 , C07D403/14 , C07D267/14
CPC分类号： A61K31/553 , A61K31/55 , C07D223/08 , C07D267/14 , C07D281/10 , C07D403/12 , C07D403/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D487/04 , C07D498/04
摘要： Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
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公开(公告)号：US11485710B2
公开(公告)日：2022-11-01
申请号：US17156478
申请日：2021-01-22
发明人： Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Claude-Marie Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC分类号： A61K31/415 , C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D403/06 , C07D409/06 , C07D413/04
摘要： Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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公开(公告)号：US20210253532A1
公开(公告)日：2021-08-19
申请号：US17156478
申请日：2021-01-22
发明人： Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Claude-Marie Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC分类号： C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , A61K31/415 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D403/06 , C07D409/06 , C07D413/04
摘要： Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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公开(公告)号：US10899716B2
公开(公告)日：2021-01-26
申请号：US16778206
申请日：2020-01-31
发明人： Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Claude-Marie Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC分类号： A61K31/4439 , C07D401/06 , C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , A61K31/415 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D403/06 , C07D409/06 , C07D413/04
摘要： Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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公开(公告)号：US20190262356A1
公开(公告)日：2019-08-29
申请号：US16408718
申请日：2019-05-10
发明人： Jae U. JEONG , Deepak Bandyopadhyay , Patrick M. Eidam , Philip Anthony Harris , Jianxing Kang , Bryan Wayne King , Ami Lakdawala Shah , Lara Kathryn Leister , Attiq Rahman , Joshi M. Ramanjulu , Clark A. Sehon , Robert Singhaus, JR. , Daohua Zhang
IPC分类号： A61K31/553 , C07D413/14 , C07D403/14 , C07D409/12 , C07D413/12 , C07D417/12 , A61K31/55 , C07D267/14 , C07D498/04 , C07D281/10 , C07D223/08 , C07D403/12 , C07D487/04
摘要： Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
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