公开(公告)号：US20090158470A1

公开(公告)日：2009-06-18

申请号：US12287379

申请日：2008-10-07

Applicant: Goutam Gupta

Inventor： Goutam Gupta

IPC: A01H5/00 ,  C12P21/02 ,  C12N9/66 ,  C12N5/10 ,  C12N15/63 ,  C07K2/00 ,  C07K14/435 ,  C07H21/00 ,  A01N37/18

CPC classification number: C12N15/8281 ,  C07K14/43563 ,  C07K14/4723 ,  C07K2319/00

Abstract: Chimeric anti-microbial proteins, compositions, and methods for the therapeutic and prophylactic treatment of plant diseases caused by the bacterial pathogen Xylella fastidiosa are provided. The anti-microbial proteins of the invention generally comprise a surface recognition domain polypeptide, capable of binding to a bacterial membrane component, fused to a bacterial lysis domain polypeptide, capable of affecting lysis or rupture of the bacterial membrane, typically via a fused polypeptide linker. In particular, methods and compositions for the treatment or prevention of Pierce's disease of grapevines are provided. Methods for the generation of transgenic Vitus vinefera plants expressing xylem-secreted anti-microbial chimeras are also provided.

Abstract translation: 提供了用于治疗和预防由细菌病原体Xylella fastidiosa引起的植物疾病的嵌合抗微生物蛋白质，组合物和方法。 本发明的抗微生物蛋白质通常包含能够结合细菌膜组分的表面识别结构域多肽，细菌膜组分与细菌裂解结构域多肽融合，能够影响细菌膜的裂解或破裂，通常通过融合的多肽接头 。 特别地，提供了用于治疗或预防葡萄藤皮尔斯氏病的方法和组合物。 还提供了用于产生表达木质部分泌的抗微生物嵌合体的转基因藤蔓植物的方法。

公开(公告)号：US20050257285A1

公开(公告)日：2005-11-17

申请号：US10846172

申请日：2004-05-14

Applicant: Goutam Gupta

Inventor： Goutam Gupta

IPC: A01H1/00 ,  C07H21/04 ,  C07K14/435 ,  C07K14/47 ,  C12N5/04 ,  C12N9/24 ,  C12N15/82

CPC classification number: C12N15/8281 ,  C07K14/43563 ,  C07K14/4723 ,  C07K2319/00

Abstract: Chimeric anti-microbial proteins, compositions, and methods for the therapeutic and prophylactic treatment of plant diseases caused by the bacterial pathogen Xylella fastidiosa are provided. The anti-microbial proteins of the invention generally comprise a surface recognition domain polypeptide, capable of binding to a bacterial membrane component, fused to a bacterial lysis domain polypeptide, capable of affecting lysis or rupture of the bacterial membrane, typically via a fused polypeptide linker. In particular, methods and compositions for the treatment or prevention of Pierce's disease of grapevines are provided. Methods for the generation of transgenic Vitus vinefera plants expressing xylem-secreted anti-microbial chimeras are also provided.

Abstract translation: 提供了用于治疗和预防由细菌病原体Xylella fastidiosa引起的植物疾病的嵌合抗微生物蛋白质，组合物和方法。 本发明的抗微生物蛋白质通常包含能够结合细菌膜组分的表面识别结构域多肽，细菌膜组分与细菌裂解结构域多肽融合，能够影响细菌膜的裂解或破裂，通常通过融合的多肽接头 。 特别地，提供了用于治疗或预防葡萄藤皮尔斯氏病的方法和组合物。 还提供了用于产生表达木质部分泌的抗微生物嵌合体的转基因藤蔓植物的方法。

公开(公告)号：US5559163A

公开(公告)日：1996-09-24

申请号：US298730

申请日：1994-08-31

Applicant: William R. Dawson ,  Goutam Gupta

Inventor： William R. Dawson ,  Goutam Gupta

IPC: C08F2/50 ,  C09D4/00

CPC classification number: C09D4/00

Abstract: UV curable coatings comprising at least one photoinitiator and at least one photopolymerizable UV absorber, wherein the photoinitiator has the ability to absorb a significant portion of the total energy needed to cure the coating from wavelengths in which the UV absorber does not appreciably absorb.

Abstract translation: 包含至少一种光引发剂和至少一种可光聚合紫外线吸收剂的紫外光固化涂料，其中光引发剂具有从UV吸收剂不明显吸收的波长吸收固化涂层所需的总能量的很大部分的能力。