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公开(公告)号：US07121227B2
公开(公告)日：2006-10-17
申请号：US10626115
申请日：2003-07-24
IPC分类号： A01K61/02
摘要： The invention relates to methods, compositions and kits for improving the raising of pre-adult anadromous fish, or preparing pre-adult anadromous fish for transfer to seawater. The methods involve adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to increase expression and/or sensitivity of at least one PVCR; and adding feed for fish consumption to the freshwater, wherein the feed comprises an amount of NaCl sufficient to contribute to a significantly increased level of the PVCR modulator in serum of the pre-adult anadromous fish.
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公开(公告)号：US06655318B2
公开(公告)日：2003-12-02
申请号：US10270876
申请日：2002-10-11
IPC分类号： A01K6100
摘要： The invention relates to methods, compositions and kits for improving the raising of pre-adult anadromous fish, or preparing pre-adult anadromous fish for transfer to seawater. The methods involve adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to increase expression and/or sensitivity of at least one PVCR; and adding feed for fish consumption to the freshwater, wherein the feed comprises an amount of NaCl sufficient to contribute to a significantly increased level of the PVCR modulator in serum of the pre-adult anadromous fish.
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公开(公告)号：US06564747B2
公开(公告)日：2003-05-20
申请号：US09975553
申请日：2001-10-11
IPC分类号： A01K6100
摘要： The invention relates to methods, compositions and kits for improving the raising of pre-adult anadromous fish, or preparing pre-adult anadromous fish for transfer to seawater. The methods involve adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to increase expression and/or sensitivity of at least one PVCR; and adding feed for fish consumption to the freshwater, wherein the feed comprises an amount of NaCl sufficient to contribute to a significantly increased level of the PVCR modulator in serum of the pre-adult anadromous fish.
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公开(公告)号：US06463882B1
公开(公告)日：2002-10-15
申请号：US09687373
申请日：2000-10-12
IPC分类号： A01K6100
CPC分类号： A01K63/04 , A01K61/10 , A01K61/80 , A01K61/85 , A23K20/142 , A23K20/147 , A23K20/20 , A23K20/22 , A23K50/80 , Y02A40/81 , Y02A40/845
摘要： The invention relates to methods, compositions and kits for raising marine fish in freshwater. The methods involve adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to increase expression and/or sensitivity of at least one PVCR; and adding feed for fish consumption to the freshwater, wherein the feed comprises an amount of NaCl sufficient to contribute to a significant increased level of the PVCR modulator in serum of the marine fish.
摘要翻译： 本发明涉及用于在淡水中养殖海鱼的方法，组合物和试剂盒。 所述方法包括以足以增加至少一个PVCR的表达和/或敏感性的量向淡水中加入至少一种多价阳离子感应受体（PVCR）调节剂; 并向淡水添加鱼类消费的饲料，其中饲料包含一定量的NaCl，足以有助于海鱼血清中PVCR调节剂的显着提高。
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公开(公告)号：US07055461B2
公开(公告)日：2006-06-06
申请号：US10851047
申请日：2004-05-21
申请人： H. William Harris, Jr. , Steven Jury , David R. Russell , Jacqueline Nearing , Marlies Betka , Timothy Linley , Edward M. Brown
发明人： H. William Harris, Jr. , Steven Jury , David R. Russell , Jacqueline Nearing , Marlies Betka , Timothy Linley , Edward M. Brown
IPC分类号： A01K61/00
CPC分类号： C07K14/461 , A01K79/00 , A01K79/02 , A23K50/80
摘要： The present invention relates to methods of imprinting fish in freshwater with at least one odorant for the fish and causing the imprinted fish to react to the odorant in seawater, wherein the fish are maintained in freshwater prior to transfer to seawater, The method includes: adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to modulate expression and/or sensitivity of at least one PVCR, the PVCR modulator being one which alters olfactory sensing of the fish to the odorant; adding feed for fish consumption to the freshwater, the feed containing the odorant and an amount of NaCl sufficient to contribute to a significantly increased level of the PVCR modulator in serum of the fish upon consumption of the feed, whereby the fish are imprinted with the odorant; transferring the imprinted fish to seawater; and providing a source of said odorant in the seawater to which the imprinted fish are transferred, thereby causing the imprinted fish to react to said odorant. The present invention also includes methods of homing or attracting fish, as well as methods for repelling fish by modulating the expression and/or sensitivity of the PVCR in the olfactory apparatus of the fish.
摘要翻译： 本发明涉及将淡水中的鱼印在鱼上的至少一种气味剂，并使印迹鱼与海水中的加臭剂反应的方法，其中鱼在转移到海水之前保持在淡水中。该方法包括：加入 至少一种多价阳离子感应受体（PVCR）调节剂，其量足以调节至少一个PVCR的表达和/或敏感性，PVCR调节剂是将鱼的嗅觉感测改变为加臭剂的PVCR调节剂; 向淡水添加饲料，含有气味剂的饲料和一定量的NaCl足以有助于在饲料消耗时鱼血清中PVCR调节剂的水平显着提高，由此将鱼加上加味剂 ; 将印迹鱼转移到海水中; 并在所述海水中提供所述加臭剂的来源，所述海水中转印有所述印迹鱼，从而使所述印迹鱼与所述加臭剂反应。 本发明还包括归巢或吸引鱼的方法，以及通过调节鱼的嗅觉装置中PVCR的表达和/或敏感性来排斥鱼的方法。
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公开(公告)号：US06979559B2
公开(公告)日：2005-12-27
申请号：US10125792
申请日：2002-04-18
CPC分类号： C07K14/705 , A01K2227/40 , A61K38/00 , C07K2319/00
摘要： The present invention encompasses three full length nucleic acid and amino acid sequences for PolyValent Cation-Sensing Receptors (PVCR) in Atlantic Salmon. These PVCR have been named SalmoKCaR#1, SalmoKCaR#2, and SalmoKCaR#3. The present invention includes homologs thereof, antibodies thereto, and methods for assessing SalmoKCaR nucleic acid molecules and polypeptides. The present invention further includes plasmids, vectors, host cells containing the nucleic acid sequences of SalmoKCaR #1,2 and/or 3.
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公开(公告)号：US06979558B2
公开(公告)日：2005-12-27
申请号：US10125778
申请日：2002-04-18
CPC分类号： C07K14/705 , A01K2227/40 , A61K38/00 , C07K2319/00
摘要： The present invention encompasses three full length nucleic acid and amino acid sequences for PolyValent Cation-Sensing Receptors (PVCR) in Atlantic Salmon. These PVCR have been named SalmoKCaR#1, SalmoKCaR#2, and SalmoKCaR#3. The present invention includes homologs thereof, antibodies thereto, and methods for assessing SalmoKCaR nucleic acid molecules and polypeptides. The present invention further includes plasmids, vectors, host cells containing the nucleic acid sequences of SalmoKCaR #1,2 and/or 3.
摘要翻译： 本发明涵盖了大西洋鲑鱼中PolyValent阳离子感应受体（PVCR）的三个全长核酸和氨基酸序列。 这些PVCR已被命名为SalmoKCaR＃1，SalmoKCaR＃2和SalmoKCaR＃3。 本发明包括其同系物，其抗体，以及评估SalmoKCaR核酸分子和多肽的方法。 本发明还包括质粒，载体，含有SalmoKCaR＃1,2和/或3的核酸序列的宿主细胞。
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公开(公告)号：US07101988B2
公开(公告)日：2006-09-05
申请号：US10410885
申请日：2003-04-09
CPC分类号： C12Q1/6888 , A01K2227/40 , A61K38/00 , C07K14/705 , C07K2319/00 , C12Q2600/136 , C12Q2600/158
摘要： The present invention encompasses four full length nucleic acid and amino acid sequences for PolyValent Cation-Sensing Receptors (PVCR) in Atlantic Salmon. These PVCR have been named SalmoKCaR#1, SalmoKCaR#2, SalmoKCaR#3, and SalmoKCaR#4. The present invention includes homologs thereof, antibodies thereto, and methods for assessing SalmoKCaR nucleic acid molecules and polypeptides. The present invention further includes plasmids, vectors, host cells containing the nucleic acid sequences of SalmoKCaR #1,2 3 and/or 4.
摘要翻译： 本发明涵盖了大西洋鲑鱼中PolyValent阳离子感应受体（PVCR）的四个全长核酸和氨基酸序列。 这些PVCR已被命名为SalmoKCaR＃1，SalmoKCaR＃2，SalmoKCaR＃3和SalmoKCaR＃4。 本发明包括其同系物，其抗体，以及评估SalmoKCaR核酸分子和多肽的方法。 本发明还包括质粒，载体，含有SalmoKCaR＃1,23和/或4的核酸序列的宿主细胞。
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公开(公告)号：US06951739B2
公开(公告)日：2005-10-04
申请号：US10125772
申请日：2002-04-18
CPC分类号： C07K14/705 , A01K2227/40 , A61K38/00 , C07K2319/00
摘要： The present invention encompasses three full length nucleic acid and amino acid sequences for PolyValent Cation-Sensing Receptors (PVCR) in Atlantic Salmon. These PVCR have been named SalmoKCaR#1, SalmoKCaR#2, and SalmoKCaR#3. The present invention includes homologs thereof, antibodies thereto, and methods for assessing SalmoKCaR nucleic acid molecules and polypeptides. The present invention further includes plasmids, vectors, host cells containing the nucleic acid sequences of SalmoKCaR #1, 2 and/or 3.
摘要翻译： 本发明涵盖了大西洋鲑鱼中PolyValent阳离子感应受体（PVCR）的三个全长核酸和氨基酸序列。 这些PVCR已被命名为SalmoKCaR＃1，SalmoKCaR＃2和SalmoKCaR＃3。 本发明包括其同系物，其抗体，以及评估SalmoKCaR核酸分子和多肽的方法。 本发明还包括质粒，载体，含有SalmoKCaR＃1,2和/或3的核酸序列的宿主细胞。
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公开(公告)号：US20070031864A1
公开(公告)日：2007-02-08
申请号：US11446813
申请日：2006-06-05
申请人： H. Harris , Jacqueline Nearing , Marlies Betka
发明人： H. Harris , Jacqueline Nearing , Marlies Betka
CPC分类号： C12Q1/6888 , A01K2227/40 , A61K38/00 , C07K14/705 , C07K2319/00 , C12Q2600/136 , C12Q2600/158
摘要： The present invention encompasses four full length nucleic acid and amino acid sequences for PolyValent Cation-Sensing Receptors (PVCR) in Atlantic Salmon. These PVCR have been named SalmoKCaR#1, SalmoKCaR#2, SalmoKCaR#3, and SalmoKCaR#4. The present invention includes homologs thereof, antibodies thereto, and methods for assessing SalmoKCaR nucleic acid molecules and polypeptides. The present invention further includes plasmids, vectors, host cells containing the nucleic acid sequences of SalmoKCaR #1, 2 3 and/or 4.
摘要翻译： 本发明涵盖了大西洋鲑鱼中PolyValent阳离子感应受体（PVCR）的四个全长核酸和氨基酸序列。 这些PVCR已被命名为SalmoKCaR＃1，SalmoKCaR＃2，SalmoKCaR＃3和SalmoKCaR＃4。 本发明包括其同系物，其抗体，以及评估SalmoKCaR核酸分子和多肽的方法。 本发明还包括质粒，载体，含有SalmoKCaR＃1,2,3和/或4的核酸序列的宿主细胞。
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