公开(公告)号：US09074937B2

公开(公告)日：2015-07-07

申请号：US13754283

申请日：2013-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Huei Pei Kuo ,  Zhiyong Li ,  Shih-Yuan Wang ,  Steven J. Barcelo ,  Ansoon Kim ,  Gary Gibson ,  Alexandre M Bratkovski

IPC: G01N21/00 ,  G01J3/44 ,  G01J3/02 ,  G01J3/28

CPC classification number: G01J3/44 ,  G01J3/0208 ,  G01J3/0294 ,  G01J3/2803 ,  G01J3/4406

Abstract: According to an example, apparatuses for performing multiple concurrent spectral analyzes on a sample under test include an optical system to concurrently direct a plurality of light beams onto analytes at multiple locations on the sample under test, in which the plurality of light beams cause light in either or both of a Raman spectra and a non-Raman spectra to be emitted from the analytes at the multiple locations of the sample under test. The apparatuses also include a detector to concurrently acquire a plurality of spectral measurements of the light emitted from the analytes at the multiple locations of the sample under test. Example methods of performing spectral analysis include use of the apparatuses.

Abstract translation: 根据一个示例，用于对被测试样品进行多次同时光谱分析的装置包括：一个光学系统，用于将多个光束同时引导到被测样品上的多个位置上的分析物上，其中多个光束使得光 在待测样品的多个位置处从分析物中发射的拉曼光谱和非拉曼光谱中的任一者或两者。 这些装置还包括一个检测器，用于同时获取在待测试样品的多个位置处从分析物发射的光的多个光谱测量。 执行光谱分析的示例方法包括使用这些装置。

公开(公告)号：US20140211199A1

公开(公告)日：2014-07-31

申请号：US13754283

申请日：2013-01-30

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Huei Pei Kuo ,  Zhiyong Li ,  Shih-Yuan Wang ,  Steven J. Barcelo ,  Ansoon Kim ,  Gary Gibson ,  Alexandre M. Bratkovski

IPC: G01J3/28 ,  G01J3/44

CPC classification number: G01J3/44 ,  G01J3/0208 ,  G01J3/0294 ,  G01J3/2803 ,  G01J3/4406

Abstract: According to an example, apparatuses for performing multiple concurrent spectral analyses on a sample under test include an optical system to concurrently direct a plurality of light beams onto analytes at multiple locations on the sample under test, in which the plurality of light beams cause light in either or both of a Raman spectra and a non-Raman spectra to be emitted from the analytes at the multiple locations of the sample under test. The apparatuses also include a detector to concurrently acquire a plurality of spectral measurements of the light emitted from the analytes at the multiple locations of the sample under test. Example methods of performing spectral analysis include use of the apparatuses.

Abstract translation: 根据一个示例，用于对被测试样品进行多次同时光谱分析的装置包括：一个光学系统，用于将多个光束同时引导到被测样品上的多个位置上的分析物上，其中多个光束使得光 在待测样品的多个位置处从分析物中发射的拉曼光谱和非拉曼光谱中的任一者或两者。 这些装置还包括一个检测器，用于同时获取在待测试样品的多个位置处从分析物发射的光的多个光谱测量。 执行光谱分析的示例方法包括使用这些装置。

公开(公告)号：US20140209463A1

公开(公告)日：2014-07-31

申请号：US13753796

申请日：2013-01-30

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Gary Gibson ,  Alexandre M. Bratkovski ,  Zhiyong Li ,  Steven J. Barcelo ,  Zhang-Lin Zhou

IPC: G01N21/47

CPC classification number: B03C5/028 ,  B03C5/005 ,  B03C2201/26 ,  B82Y20/00

Abstract: The present disclosure is drawn to traveling wave dielectrophoresis sensing devices and associated methods. In an example, a traveling wave dielectrophoresis sensing device can comprise an array of electromagnetic field enhancing nanostructures attached to the substrate, the electromagnetic field enhancing nanostructures including a metal; a plurality of conductive element electrically associated with the electromagnetic field enhancing nanostructures; and a controller for applying alternating and out of phase potential to the plurality of conductive elements to form traveling wave dielectrophoretic forces within the array.

Abstract translation: 本公开涉及行波介电电泳感测装置及相关方法。 在一个示例中，行波介电电泳感测装置可以包括附着到基底的电磁场增强纳米结构的阵列，包括金属的电磁场增强纳米结构; 与电磁场增强纳米结构电连接的多个导电元件; 以及控制器，用于向所述多个导电元件施加交变和异相电位，以在所述阵列内形成行波介电电泳力。

公开(公告)号：US09739717B2

公开(公告)日：2017-08-22

申请号：US15289050

申请日：2016-10-07

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven J. Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Zhang-Lin Zhou ,  Gary Gibson

IPC: G01N21/65 ,  B82Y40/00

CPC classification number: G01N21/658 ,  B82Y40/00 ,  Y10S977/882

Abstract: According to an example, methods for forming three-dimensional (3-D) nano-particle assemblies include depositing SES elements onto respective tips of nano-fingers, in which the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of groups of adjacent ones of the nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to be bonded together when the nano-fingers are partially collapsed. The methods also include causing the nano-fingers to partially collapse toward adjacent ones of the nano-fingers to cause a plurality of SES elements on respective groups of the nano-fingers to be in relatively close proximities to each other and form respective clusters of SES elements, introducing additional particles that are to attach onto the clusters of SES elements, and causing the clusters of SES elements to detach from the nano-fingers.

公开(公告)号：US09567214B2

公开(公告)日：2017-02-14

申请号：US14763491

申请日：2013-01-25

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Zhang-Lin Zhou ,  Zhiyong Li ,  Steven J. Barcelo

IPC: B82Y15/00 ,  G01N21/65 ,  G01N21/552 ,  G01N21/64

CPC classification number: B82Y15/00 ,  G01N21/554 ,  G01N21/648 ,  G01N21/658 ,  G01N2021/651

Abstract: The present disclosure is drawn to chemical sensing devices and associated methods. In one example, a chemical sensing device can include a substrate; an elongated nanostructure having an attachment end and a free end opposite the attachment end, the attachment end affixed to the substrate and the free end including a metal; and a metal oxide coating applied to the elongated nanostructure. In one example, a functional group can be attached to the coating via a covalent bond.

Abstract translation: 本公开涉及化学感测装置和相关方法。 在一个示例中，化学感测装置可以包括基底; 细长的纳米结构，其具有附接端和与所述附接端相对的自由端，所述附接端固定到所述基底并且所述自由端包括金属; 以及施加到细长纳米结构的金属氧化物涂层。 在一个实例中，可以通过共价键将官能团连接到涂层上。

公开(公告)号：US20170023483A1

公开(公告)日：2017-01-26

申请号：US15289050

申请日：2016-10-07

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven J. Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Zhang-Lin Zhou ,  Gary Gibson

IPC: G01N21/65

CPC classification number: G01N21/658 ,  B82Y40/00 ,  Y10S977/882

Abstract: According to an example, methods for forming three-dimensional (3-D) nano-particle assemblies include depositing SES elements onto respective tips of nano-fingers, in which the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of groups of adjacent ones of the nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to be bonded together when the nano-fingers are partially collapsed. The methods also include causing the nano-fingers to partially collapse toward adjacent ones of the nano-fingers to cause a plurality of SES elements on respective groups of the nano-fingers to be in relatively close proximities to each other and form respective clusters of SES elements, introducing additional particles that are to attach onto the clusters of SES elements, and causing the clusters of SES elements to detach from the nano-fingers.

Abstract translation: 根据一个实例，用于形成三维（3-D）纳米颗粒组件的方法包括将SES元件沉积到纳米手指的各个尖端上，其中纳米手指以彼此足够接近的方式排列，使得 纳米手指的相邻组的尖端彼此靠近，使得当纳米手指被部分折叠时，尖端上的SES元件能够结合在一起。 所述方法还包括使纳米指部分相对于纳米手指部分地折叠，以使纳米手指的相应组上的多个SES元件彼此相对接近并形成相应的SES簇 引入附加到SES元件簇上的附加颗粒，并使SES元件簇与纳米手指分离。

公开(公告)号：US20140209837A1

公开(公告)日：2014-07-31

申请号：US13754404

申请日：2013-01-30

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Steven J. Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Zhang-Lin Zhou ,  Gary Gibson

IPC: G01N21/65

CPC classification number: G01N21/658 ,  B82Y40/00 ,  Y10S977/882

Abstract: According to an example, methods for forming three-dimensional (3-D) nano-particle assemblies include depositing SES elements onto respective tips of nano-fingers, in which the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of groups of adjacent ones of the nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to be bonded together when the nano-fingers are partially collapsed. The methods also include causing the nano-fingers to partially collapse toward adjacent ones of the nano-fingers to cause a plurality of SES elements on respective groups of the nano-fingers to be in relatively close proximities to each other and form respective clusters of SES elements, introducing additional particles that are to attach onto the clusters of SES elements, and causing the clusters of SES elements to detach from the nano-fingers.

Abstract translation: 根据一个实例，用于形成三维（3-D）纳米颗粒组件的方法包括将SES元件沉积到纳米手指的各个尖端上，其中纳米手指以彼此足够接近的方式排列，使得 纳米手指的相邻组的尖端彼此靠近，使得当纳米手指被部分折叠时，尖端上的SES元件能够结合在一起。 所述方法还包括使纳米指部分相对于纳米手指部分地折叠，以使纳米手指的相应组上的多个SES元件彼此相对接近并形成相应的SES簇 引入附加到SES元件簇上的附加颗粒，并使SES元件簇与纳米手指分离。

公开(公告)号：US20130196449A1

公开(公告)日：2013-08-01

申请号：US13801227

申请日：2013-03-13

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Ansoon Kim ,  Huei Pei Kuo ,  Zhiyong Li ,  Steven J. Barcelo ,  Zhang-Lin Zhou ,  Gary Gibson

IPC: G01N21/65

CPC classification number: G01N21/658

Abstract: An electrically driven device for surface enhanced Raman spectroscopy includes a substrate, a Raman signal-amplifying structure positioned on the substrate, and an analyte receptor attached to a structure chosen from i) the Raman signal-amplifying structure, or ii) the substrate near the Raman signal-amplifying structure, or iii) combinations of i and ii. The analyte receptor has a selective binding affinity for an analyte. Conductive elements are positioned relative to one another and to the analyte receptor such that the conductive elements together produce an electric field in the vicinity of the analyte receptor when a voltage bias is applied between the conductive elements.

Abstract translation: 用于表面增强拉曼光谱的电驱动器件包括衬底，位于衬底上的拉曼信号放大结构和附着于从i）拉曼信号放大结构的结构的分析物受体，或ii） 拉曼信号放大结构，或iii）i和ii的组合。 分析物受体对分析物具有选择性结合亲和力。 导电元件相对于彼此和分析物受体定位，使得当在导电元件之间施加电压偏压时，导电元件在分析物接收体附近一起产生电场。