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14 条记录 (耗时 0.061 秒)

    Pyridone derivative
    12.
    发明授权
    Pyridone derivative 失效
    吡啶酮衍生物

    公开(公告)号：US07732456B2

    公开(公告)日：2010-06-08

    申请号：US10591373

    申请日：2005-03-04

    申请人： Norikazu Otake ,  Yuji Haga ,  Akira Naya ,  Sayaka Mizutani ,  Akio Kanatani

    发明人： Norikazu Otake ,  Yuji Haga ,  Akira Naya ,  Sayaka Mizutani ,  Akio Kanatani

    IPC分类号： A61K31/444 ,  C07D401/02

    CPC分类号： C07D213/69 ,  C07D237/16 ,  C07D239/52 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D409/14 ,  C07D451/02 ,  C07D471/04

    摘要： The invention provides pyridone derivatives represented by a general formula (I) [in the formula, R1 and R2 may be same or different and stands for H, etc., or R1 and R2 may form an aliphatic nitrogen-containing heterocyclic group together with the N to which they bind; X1-X3 may be same or different and stand for methine or N, provided not all of them simultaneously stand for nitrogen; X4-X7 may be same or different and stand for methine or N, provided that three or more of them do not simultaneously stand for N; Y1 and Y3 may be same or different and stand for single bond, —O—, —NR—, —S—, etc; Y2 stands for lower lkylene, etc.; R stands for H, etc., L stands for methylene; Z1 and Z2 may be same or different and stand for single bond or lower alkylene; or R1, L and Z2 may form an aliphatic nitrogen-containing heterocyclic group with the N to which R1 binds; and Ar stands for aromatic carbocyclic group, etc.].

    摘要翻译： 本发明提供由通式（I）表示的吡啶酮衍生物[在该式中，R 1和R 2可以相同或不同，代表H等，或者R 1和R 2可以与脂族含氮杂环基一起形成 他们绑定的N X1-X3可以相同或不同，代替次甲基或N，但不是全部同时代表氮; X4-X7可以相同或不同，代表次甲基或N，条件是它们中的三个或更多不同时代表N; Y1和Y3可以相同或不同，代表单键，-O-，-NR-，-S-等; Y2代表低级亚烷基等; R代表H等，L代表亚甲基; Z 1和Z 2可以相同或不同，代表单键或低级亚烷基; 或R1，L和Z2可以与R1结合的N形成脂族含氮杂环基; 和Ar代表芳族碳环基团等]。

    Pyridone derivative
    13.
    发明申请
    Pyridone derivative 失效
    吡啶酮衍生物

    公开(公告)号：US20070208046A1

    公开(公告)日：2007-09-06

    申请号：US10591373

    申请日：2005-03-04

    申请人： Norikazu Otake ,  Yuji Haga ,  Akira Naya ,  Sayaka Mizutani ,  Akio Kanatani

    发明人： Norikazu Otake ,  Yuji Haga ,  Akira Naya ,  Sayaka Mizutani ,  Akio Kanatani

    IPC分类号： A61K31/513 ,  A61K31/444 ,  A61K31/4412 ,  C07D403/02 ,  C07D401/02

    CPC分类号： C07D213/69 ,  C07D237/16 ,  C07D239/52 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D409/14 ,  C07D451/02 ,  C07D471/04

    摘要： The invention provides pyridone derivatives represented by a general formula (I) [in the formula, R1 and R2 may be same or different and stands for H, etc., or R1 and R2 may form an aliphatic nitrogen-containing heterocyclic group together with the N to which they bind; X1-X3 may be same or different and stand for methine or N, provided not all of them simultaneously stand for nitrogen; X4-X7 may be same or different and stand for methine or N, provided that three or more of them do not simultaneously stand for N; Y1 and Y3 may be same or different and stand for single bond, —O—, —NR—, —S—, etc; Y2 stands for lower alkylene, etc.; R stands for H, etc., L stands for methylene; Z1 and Z2 may be same or different and stand for single bond or lower alkylene; or R1, L and Z2 may form an aliphatic nitrogen-containing heterocyclic group with the N to which R1 binds; and Ar stands for aromatic carbocyclic group, etc.].

    摘要翻译： 本发明提供由通式（I）表示的吡啶酮衍生物[在式中，R 1和R 2可以相同或不同，代表H等， 或R 1和R 2可以与它们所键合的N一起形成脂族含氮杂环基; X 1 -X 3可以相同或不同，代表次甲基或N，但并不全部同时代表氮; X 4 -X 7可以相同或不同，代表次甲基或N，条件是它们中的三个或更多个不同时代表N; Y 1和Y 3可以相同或不同，代表单键，-O-，-NR-，-S-等; Y 2代表低级亚烷基等; R代表H等，L代表亚甲基; Z 1和Z 2可以相同或不同，代表单键或低级亚烷基; 或R 1，L和Z 2可以与R 1结合的N形成脂族含氮杂环基; 和Ar代表芳族碳环基团等]。