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21 条记录 (耗时 0.031 秒)

    Method and apparatus for the determination of electron density in a part volume of a body
    11.
    发明授权
    Method and apparatus for the determination of electron density in a part volume of a body 失效
    用于确定身体部分体积中的电子密度的方法和装置

    公开(公告)号：US3961186A

    公开(公告)日：1976-06-01

    申请号：US509514

    申请日：1974-09-26

    申请人： Ib Leunbach

    发明人： Ib Leunbach

    IPC分类号： G01N23/203 ,  A61B6/00 ,  G01N23/02 ,  G01N23/20

    CPC分类号： G01N23/02

    摘要： A method of and an apparatus for the determination of the electron density of small volumes of a body. Two narrow beams of ionizing radiation of substantially equal intensity are subsequently directed through the small volume in two different directions. The intensity of the transmitted radiation as well as the scattered radiation along said two directions is measured extra-corporally, which measurements are employed in computing the electron density of the small volume. The employed radiation is of such high energy that the Compton effect will be the wholly dominant absorption phenomenon in the volume as well as in the radiation paths in the two mentioned directions, and that the change in the absorption cross-section from primary to secondary radiation caused by the Compton shift will be substantial.

    摘要翻译： 用于确定体积小体积的电子密度的方法和装置。 基本上相同强度的两束电离辐射光束随后在两个不同的方向上穿过小体积。 辐射辐射的强度以及沿着两个方向的散射辐射是外部测量的，这些测量用于计算小体积的电子密度。 所使用的辐射具有如此高的能量，康普顿效应将是在上述两个方向上的体积以及辐射路径中的完全主要的吸收现象，并且吸收截面从初级辐射到次级辐射的变化 造成康普顿转变将会很大。

    Contrast agents
    12.
    发明申请
    Contrast agents 审中-公开
    对比剂

    公开(公告)号：US20070031339A1

    公开(公告)日：2007-02-08

    申请号：US10560065

    申请日：2004-11-06

    申请人： Oskar Axelsson ,  Ib Leunbach ,  Magnus Karlssov

    发明人： Oskar Axelsson ,  Ib Leunbach ,  Magnus Karlssov

    IPC分类号： A61K49/04

    CPC分类号： A61K49/0428 ,  A61K49/0419 ,  B22F1/0018 ,  B22F1/0059 ,  B22F9/24 ,  B82Y5/00 ,  B82Y30/00

    摘要： The present invention relates to particles comprising cores of tungsten or tungsten in mixture with other metallic elements as the contrast enhancing material wherein said core are coated, to pharmaceuticals containing such particles, and to the use of such pharmaceuticals specifically as contrast agents in diagnostic imaging, in particular in X-ray imaging.

    摘要翻译： 本发明涉及包含与其它金属元素作为对比增强材料的其它金属元素的钨或钨的核心的颗粒，其中所述芯被涂覆到包含这种颗粒的药物中，以及在诊断成像中特异性地用作造影剂的这种药物的用途， 特别是在X射线成像中。

    Method of electron spin resonance enhanced magnetic resonance imaging
    15.
    发明授权
    Method of electron spin resonance enhanced magnetic resonance imaging 失效
    电子自旋共振增强磁共振成像方法

    公开(公告)号：US4984573A

    公开(公告)日：1991-01-15

    申请号：US295031

    申请日：1988-12-23

    申请人： Ib Leunbach

    发明人： Ib Leunbach

    IPC分类号： A61B5/055 ,  A61K49/00 ,  A61K49/20 ,  G01N24/10 ,  G01R33/28 ,  G01R33/44 ,  G01R33/48 ,  G01R33/62

    CPC分类号： G01R33/5601 ,  A61K49/20 ,  G01R33/282 ,  G01R33/62 ,  Y10T436/24

    摘要： A method of generating a magnetic resonance image of a sample comprising introducing into the sample a contrast medium comprising a paramagnetic material having an electron spin resonance transition having a linewidth of 1 Gauss or less; exposing the sample to a first radiation of a frequency selected to excite nuclear spin transitions in selective nuclei in the sample and exposing the sample to a second radiation of a frequency which excites electron spin transitions coupled to nuclear spin transitions of at least some nuclei, the second radiation being of a frequency selected to excite an electron spin resonance transition of the paramagnetic material; detecting free induction decay signals from the sample; and generating therefrom a magnetic resonance image of the sample.

    Magnetic resonance imaging
    17.
    发明授权
    Magnetic resonance imaging 失效
    磁共振成像

    公开(公告)号：US5203332A

    公开(公告)日：1993-04-20

    申请号：US603314

    申请日：1990-10-25

    申请人： Ib Leunbach

    发明人： Ib Leunbach

    IPC分类号： A61K49/20 ,  G01R33/28 ,  G01R33/62

    CPC分类号： G01R33/5601 ,  A61K49/20 ,  G01R33/62

    摘要： A magnetic resonance image generating apparatus comprising a first radiation source capable of emitting a first radiation of a frequency selected to excite nuclear spin transitions in selected nuclei in a sample being imaged and means for detecting free induction decay signals from said selected nuclei, characterized in that said apparatus further comprises a second radiation source capable of emitting a second radiation of a frequency selected to excite electron spin transitions coupled to the nuclear spin transitions of at least some of said selected nuclei.

    摘要翻译： 一种磁共振图像产生装置，包括第一辐射源，其能够发射选定的频率的第一辐射，以激发被成像的样品中所选择的核中的核自旋跃迁，以及用于检测来自所述选择的核的自由感应衰减信号的装置，其特征在于， 所述装置还包括能够发射频率的第二辐射的第二辐射源，所述第二辐射被选择为激发耦合到所述选择的核中的至少一些的核自旋跃迁的电子自旋跃迁。

    Stable free radical containing contrast media
    20.
    发明授权
    Stable free radical containing contrast media 失效
    稳定的自由基含有造影剂

    公开(公告)号：US5322065A

    公开(公告)日：1994-06-21

    申请号：US613471

    申请日：1990-10-29

    申请人： Ib Leunbach

    发明人： Ib Leunbach

    IPC分类号： G01R33/28 ,  A61B5/055 ,  A61K49/00 ,  A61K49/20 ,  C07D207/16 ,  C07D207/22 ,  C07D211/44 ,  C07D211/58 ,  A61B5/05

    CPC分类号： A61K49/0002 ,  A61K49/20

    摘要： The present invention relates to a method of generating a magnetic resonance image of a sample comprising introducing into the sample a physiologically tolerable deuterated stable free radical, exposing the sample to first and second radiations of frequencies selected respectively to excite nuclear spin transitions in selected nuclei in the sample and to excite electron spin resonance transitions of the free radical coupled to nuclear spin transitions of at least some of the nuclei, detecting free induction decay signals from the sample, and generating a magnetic resonance image from these signals.

    摘要翻译： PCT No.PCT / EP89 / 00832 Sec。 371 1990年10月29日第 102（e）1990年10月29日PCT PCT 1989年7月17日PCT公布。 公开号WO90 / 00904 日本1990年2月8日。本发明涉及一种生成样品的磁共振图像的方法，包括向样品中引入生理上可耐受的氘代稳定自由基，将样品暴露于分别选择的第一和第二频率辐射以激发 在样品中选择的核中的核自旋跃迁并激发与至少一些核的核自旋跃迁耦合的自由基的电子自旋共振转变，检测来自样品的自由诱导衰变信号，以及从这些中产生磁共振图像 信号。