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公开(公告)号：US09216255B2
公开(公告)日：2015-12-22
申请号：US13148836
申请日：2010-03-04
申请人： Ursula Lanin , Bernhard Forys , Alastair Clarke , Matthew Ekman , Kirsten Goode , Michael Heald , John Hiles , Chris Smith , Andrew Martin
发明人： Ursula Lanin , Bernhard Forys , Alastair Clarke , Matthew Ekman , Kirsten Goode , Michael Heald , John Hiles , Chris Smith , Andrew Martin
CPC分类号： A61M5/322 , A61M2005/3231 , A61M2005/3235
摘要： A needle assembly (2) for a drug delivery device (1) comprises a needle seal (3), a needle retainer (4) and a needle (5). The needle retainer (4) secures the needle (5) against displacement with respect to said needle retainer (4) when a dose of drug is being delivered. The needle seal (3) is configured to push onto the needle retainer (4) after delivering the dose of the drug, thereby unlocking the needle (5) from the needle retainer (4).
摘要翻译： 用于药物输送装置（1）的针组件（2）包括针密封件（3），针保持器（4）和针（5）。 当药物剂量被输送时，针保持器（4）将针（5）固定在相对于针保持器（4）的位置上。 针状密封件（3）被配置为在递送药物的剂量之后推入针保持器（4），从而将针（5）从针保持器（4）解锁。
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公开(公告)号：US20140094752A1
公开(公告)日：2014-04-03
申请号：US14116893
申请日：2012-05-09
申请人： John Hiles
发明人： John Hiles
IPC分类号： A61F9/00
CPC分类号： A61F9/0026 , A61F9/0017 , A61M5/3287
摘要： Described is a guide device for intraocular injection comprising a base plate having an inner surface and an outer surface, a handle formed on the outer surface, and a hole formed in the base plate and extending through the inner and outer surfaces. The inner surface is adapted to contact an eye ball.
摘要翻译： 描述了一种用于眼内注射的引导装置，其包括具有内表面和外表面的基板，形成在外表面上的手柄，以及形成在基板中并延伸穿过内表面和外表面的孔。 内表面适于接触眼球。
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公开(公告)号：US09145162B2
公开(公告)日：2015-09-29
申请号：US14125143
申请日：2012-05-21
申请人： Stephen Butler , John Hiles , Mark Anthony Wilkes
发明人： Stephen Butler , John Hiles , Mark Anthony Wilkes
摘要： A collapsible steering column assembly for a vehicle comprises a shroud which surrounds a steering column shaft, a mounting bracket secured to or integral with a fixed part of the vehicle, a support bracket secured to the mounting bracket through one or more frangible connectors, a clamp mechanism which releasably secures the shroud to the support bracket, and a blocking part which is fixed in position relative to the mounting and at least in an unclamped condition of the clamp mechanism provides an additional force path between the clamp mechanism and the mounting bracket that does not pass through the support bracket. In the event that an axial load is applied to the steering assembly when the clamp mechanism is unlocked and has reached the end of its allowable travel at least some of the load is carried through the clamp mechanism and the blocking part to the mounting bracket along the additional force path.
摘要翻译： 用于车辆的可折叠转向柱组件包括围绕转向柱轴的护罩，固定到车辆的固定部分或与车辆的固定部分一体的安装支架，通过一个或多个易碎连接器固定到安装支架的支撑架，夹具 将护罩可释放地固定到支撑托架的机构，以及相对于安装件固定在适当位置并且至少在夹紧机构的非夹紧状态下的阻挡部件，在夹紧机构和安装支架之间提供附加的力路径 不能穿过支架。 在夹紧机构被解锁并且到达其允许行程的终点时轴向载荷被施加到转向组件的情况下，至少一些负载通过夹持机构和阻挡部件沿着 附加力路径。
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公开(公告)号：US08992485B2
公开(公告)日：2015-03-31
申请号：US13504057
申请日：2010-10-28
申请人： John Hiles
发明人： John Hiles
CPC分类号： A61M5/24 , A61M5/3146 , A61M5/315 , A61M2005/2407 , A61M2005/2492 , A61M2207/00 , Y10T29/49764 , Y10T29/49769 , Y10T29/49826
摘要： A drug delivery device for dispensing of a dose of a medicinal product, comprising a holder (14) for a product-containing cartridge (16), the cartridge (16) having a piston (18) slidably arranged therein in an axial direction, a piston rod (12) to be operably engaged with the cartridge's piston (18) for dispensing of a dose of the medicinal product, and at least one spacer (20) being selected according to a relative distance between piston (18) and piston rod (12) and being disposed between the piston rod (12) and the piston (18) for eliminating axial clearance between piston (18) and piston rod (12).
摘要翻译： 一种用于分配药物产品剂量的药物递送装置，包括用于产品容纳盒（16）的保持器（14），所述药筒（16）具有沿轴向方向可滑动地布置的活塞（18）， 活塞杆（12）可与药筒的活塞（18）可操作地接合，用于分配一定剂量的药用产品，以及至少一个间隔件（20），其根据活塞（18）和活塞杆（ 12）并且设置在活塞杆（12）和活塞（18）之间，以消除活塞（18）和活塞杆（12）之间的轴向间隙。
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公开(公告)号：US20130023832A1
公开(公告)日：2013-01-24
申请号：US13504057
申请日：2010-10-28
申请人： John Hiles
发明人： John Hiles
CPC分类号： A61M5/24 , A61M5/3146 , A61M5/315 , A61M2005/2407 , A61M2005/2492 , A61M2207/00 , Y10T29/49764 , Y10T29/49769 , Y10T29/49826
摘要： A drug delivery device for dispensing of a dose of a medicinal product, comprising a holder (14) for a product-containing cartridge (16), the cartridge (16) having a piston (18) slidably arranged therein in an axial direction, a piston rod (12) to be operably engaged with the cartridge's piston (18) for dispensing of a dose of the medicinal product, and at least one spacer (20) being selected according to a relative distance between piston (18) and piston rod (12) and being disposed between the piston rod (12) and the piston (18) for eliminating axial clearance between piston (18) and piston rod (12).
摘要翻译： 一种用于分配药物产品剂量的药物递送装置，包括用于产品容纳盒（16）的保持器（14），所述药筒（16）具有沿轴向方向可滑动地布置的活塞（18）， 活塞杆（12）可与药筒的活塞（18）可操作地接合，用于分配一定剂量的药用产品，以及至少一个间隔件（20），其根据活塞（18）和活塞杆（ 12）并且设置在活塞杆（12）和活塞（18）之间，以消除活塞（18）和活塞杆（12）之间的轴向间隙。
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16.发明授权公开(公告)号：US09381306B2
公开(公告)日：2016-07-05
申请号：US13702823
申请日：2011-06-09
申请人： John Hiles
发明人： John Hiles
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/31543 , A61M5/31555 , A61M5/31585
摘要： A drive member and a rotation member are rotatable with respect to a housing. The drive member comprises drive fingers, which are resilient or resiliently mounted. A slider is disposed at the drive member and is axially movable between a first position, in which the slider keeps the drive fingers constrained, and a second position, in which the drive fingers are released. A unidirectional rotational clutch engages the drive member with the rotation member. The clutch is formed by the drive fingers when the slider is in the first position. The drive member and the rotation member are disengaged when the slider is in the second position. The slider is in the first position when a unit is attached to the housing, and in the second position when the unit is removed.
摘要翻译： 驱动构件和旋转构件可相对于壳体旋转。 驱动构件包括弹性或弹性安装的驱动指状物。 滑块设置在驱动构件上并且可在第一位置和第二位置之间轴向移动，第一位置和第二位置，第一位置和第二位置之间，驱动爪被释放。 单向旋转离合器将驱动构件与旋转构件接合。 当滑块处于第一位置时，离合器由驱动指形成。 当滑块处于第二位置时，驱动构件和旋转构件脱离。 当单元附接到壳体时，滑块处于第一位置，并且在单元被移除时位于第二位置。
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公开(公告)号：US09072845B2
公开(公告)日：2015-07-07
申请号：US13642080
申请日：2011-04-21
申请人： John Hiles
发明人： John Hiles
CPC分类号： A61M5/5086 , A61J1/062 , A61J2205/40 , A61M5/24 , A61M5/3134 , A61M5/31551 , A61M5/3158 , A61M2005/2407 , A61M2205/6045 , A61M2205/6081
摘要： A keying insert for use with a cartridge assembly containing a fluid. The insert comprises a main body defining a bore that extends from a proximal end to a distal end of the main body and allows the fluid to dispense from the distal end of the cartridge through a septum. The main body includes a septum for sealing the fluid within the cartridge and a coding feature that is keyed to a cartridge holder or other dispense interface.
摘要翻译： 用于与包含流体的盒组件一起使用的键合插入件。 插入件包括限定从主体的近端延伸到远端的孔的主体，并允许流体通过隔膜从药筒的远端分配。 主体包括用于密封墨盒内的流体的隔膜和与墨盒保持器或其他分配界面键合的编码特征。
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公开(公告)号：US20140352480A1
公开(公告)日：2014-12-04
申请号：US14125143
申请日：2012-05-21
申请人： Stephen Butler , John Hiles , Mark Anthony Wilkes
发明人： Stephen Butler , John Hiles , Mark Anthony Wilkes
摘要： A collapsible steering column assembly for a vehicle comprises a shroud which surrounds a steering column shaft, a mounting bracket secured to or integral with a fixed part of the vehicle, a support bracket secured to the mounting bracket through one or more frangible connectors, a clamp mechanism which releasably secures the shroud to the support bracket, and a blocking part which is fixed in position relative to the mounting and at least in an unclamped condition of the clamp mechanism provides an additional force path between the clamp mechanism and the mounting bracket that does not pass through the support bracket. In the event that an axial load is applied to the steering assembly when the clamp mechanism is unlocked and has reached the end of its allowable travel at least some of the load is carried through the clamp mechanism and the blocking part to the mounting bracket along the additional force path.
摘要翻译： 用于车辆的可折叠转向柱组件包括围绕转向柱轴的护罩，固定到车辆的固定部分或与车辆的固定部分一体的安装支架，通过一个或多个易碎连接器固定到安装支架的支撑架，夹具 将护罩可释放地固定到支撑托架的机构，以及相对于安装件固定在适当位置并且至少在夹紧机构的非夹紧状态下的阻挡部件，在夹紧机构和安装支架之间提供附加的力路径 不能穿过支架。 在夹紧机构被解锁并且到达其允许行程的终点时轴向载荷被施加到转向组件的情况下，至少一些负载通过夹持机构和阻挡部件沿着 附加力路径。
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公开(公告)号：US20210338984A1
公开(公告)日：2021-11-04
申请号：US17245291
申请日：2021-04-30
申请人： Robert Booker , William Harris , Deborah Norris , Rupert Barton , Frances Penrose , John Hiles
发明人： Robert Booker , William Harris , Deborah Norris , Rupert Barton , Frances Penrose , John Hiles
摘要： Example deflectable catheter systems are described. An example deflectable catheter system includes a housing, an orienting member, an actuator, a first elongate member, a second elongate member, and a wire member. The housing defines a passageway. The orienting member is attached to the housing. The actuator is attached to the orienting member and is moveable between an actuator first position and an actuator second position. The first elongate member is attached to the orienting member and defines a lumen. The first elongate member is moveable between a first, substantially straight configuration when the actuator is in the actuator first position and a second, curved configuration when the actuator is in the actuator second position. The second elongate member is disposed through the passageway of the housing and extends through the lumen defined by the first elongate member. The second elongate member is rotatable relative to the first elongate member.
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公开(公告)号：US20130150786A1
公开(公告)日：2013-06-13
申请号：US13642080
申请日：2011-04-21
申请人： John Hiles
发明人： John Hiles
IPC分类号： A61M5/50
CPC分类号： A61M5/5086 , A61J1/062 , A61J2205/40 , A61M5/24 , A61M5/3134 , A61M5/31551 , A61M5/3158 , A61M2005/2407 , A61M2205/6045 , A61M2205/6081
摘要： A keying insert for use with a cartridge assembly containing a fluid. The insert comprises a main body defining a bore that extends from a proximal end to a distal end of the main body and allows the fluid to dispense from the distal end of the cartridge through a septum. The main body includes a septum for sealing the fluid within the cartridge and a coding feature that is keyed to a cartridge holder or other dispense interface.
摘要翻译： 用于与包含流体的盒组件一起使用的键合插入件。 插入件包括限定从主体的近端延伸到远端的孔的主体，并允许流体通过隔膜从药筒的远端分配。 主体包括用于密封墨盒内的流体的隔膜和与墨盒保持器或其他分配界面键合的编码特征。
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