公开(公告)号：US20170216531A1

公开(公告)日：2017-08-03

申请号：US15500684

申请日：2015-07-30

Applicant: THE JOHNS HOPKINS UNIVERSITY ,  U.S. Army Medical Research Material Command

Inventor： Luis Andres GARZA ,  Jon MEYERLE ,  Sewon KANG

IPC: A61M5/31

CPC classification number: A61M5/3134 ,  A01N1/0263 ,  A61J1/062 ,  A61J1/1468 ,  A61M5/3129 ,  A61M5/3135 ,  A61M2005/3117 ,  A61M2005/3125 ,  A61M2005/3131 ,  A61M2202/09 ,  A61M2205/3633

Abstract: An embodiment in accordance with the present invention is directed to a device for use as a cryosyringe and a cryo-storage vial. The device includes a first end and a second end and has an outer wall defining a lumen between the first and second ends. Both the first end and the second end include threads configured for attaching a first cap to the first end and a second cap to the second end. The device can also include a syringe plunger adapter, such that the cryo-storage vial is convertible into a cryosyringe to ensure sterility of the contents. Similarly, a luer-lock adapter can be included to further convert the device into a cryosyringe. The device and its components are formed from a cryo-resistant material. The device can therefore withstand liquid nitrogen temperatures necessary to preserve cell viability and be injected without compromising sterility to dispense the cellular therapy.

公开(公告)号：US20170175263A1

公开(公告)日：2017-06-22

申请号：US15128481

申请日：2015-03-24

Applicant: SiO2 Medical Products, Inc.

Inventor： Tadashi Yamamoto ,  Christopher Weikart ,  John T. Felts ,  John Berggren

IPC: C23C16/36 ,  C23C16/50 ,  C23C16/04 ,  A61M5/31 ,  B65D85/00 ,  B65D25/34 ,  B65D25/14 ,  A61M25/00 ,  C23C16/40 ,  A61J1/14

CPC classification number: C23C16/36 ,  A61J1/03 ,  A61J1/062 ,  A61J1/065 ,  A61J1/1443 ,  A61J1/1468 ,  A61M5/3129 ,  A61M25/0045 ,  A61M2205/0233 ,  B65D23/02 ,  B65D23/0821 ,  B65D25/14 ,  B65D25/34 ,  B65D85/70 ,  B65D2213/02 ,  C23C16/045 ,  C23C16/401 ,  C23C16/50

Abstract: A method of reducing static charge of a plastic container is provided. The method includes providing a PECVD coating of SiCOH, SiOx or SiOH to an external support surface of the container. The PECVD coating reduces static charge of the container compared to a reference container that is essentially identical to the container except that the reference container is uncoated.

公开(公告)号：US20170043094A1

公开(公告)日：2017-02-16

申请号：US15306878

申请日：2015-05-18

Applicant: MEDICOM INNOVATION PARTNER A/S

Inventor： Esben W. JOHANSEN ,  Niels KURE ,  Henrik LEISNER

IPC: A61M5/31 ,  A61M5/24 ,  A61M5/158 ,  A61M5/28

CPC classification number: A61M5/31 ,  A61J1/062 ,  A61M5/158 ,  A61M5/24 ,  A61M5/2448 ,  A61M5/2459 ,  A61M5/28 ,  A61M5/31596 ,  A61M2005/3128

Abstract: A medical cartridge containing multiple doses of a medical drug is disclosed. An outlet end is arranged to be connected to an injection needle for delivering the medical drug. The medical cartridge comprises a one way valve arranged in an interior part of the medical cartridge at a position near the outlet end. The one way valve allows a fluid flow from the interior of the medical cartridge towards the outlet end, but prevents a fluid flow from the outlet end towards the interior of the medical cartridge. Thereby the risk of contamination of the medical drug remaining in the cartridge is minimised.

Abstract translation: 公开了一种含有多剂医药的医用药筒。 出口端设置成连接到用于输送医疗药物的注射针。 医疗盒包括在靠近出口端的位置处布置在医疗盒的内部的单向阀。 单向阀允许流体从医疗盒的内部朝向出口端流动，但是防止流体从出口端朝向医疗盒的内部流动。 从而使残留在药筒中的药物的污染风险最小化。

公开(公告)号：US09492351B2

公开(公告)日：2016-11-15

申请号：US13295408

申请日：2011-11-14

Applicant: Matthew J. Stepovich ,  Randy Kesten ,  Jeff Zalewski

Inventor： Matthew J. Stepovich ,  Randy Kesten ,  Jeff Zalewski

IPC: A61B19/00 ,  A61J1/20 ,  A61J1/06

CPC classification number: A61J1/2075 ,  A61J1/062 ,  A61J1/2017 ,  A61J1/2089

Abstract: A liquid transfer connector comprises an enclosure holding a transfer needle and an exhaust needle. A container of donor liquid may be attached to an inlet end of the transfer needle and a container holding a recipient liquid may be attached to an outlet end of the transfer needle and an inlet end of an exhaust needle. The exhaust needle has an outlet end within the connector which releases displaced fluid into an absorbent mass which sequesters the fluid to prevent leakage.

Abstract translation: 液体转移连接器包括保持转移针和排气针的外壳。 供体液体的容器可以附接到转移针的入口端，并且容纳受体液体的容器可以附接到转移针的出口端和排气针的入口端。 排气针头具有在连接器内的出口端，其将移动的流体释放到吸收物质中，其吸收流体以防止泄漏。

公开(公告)号：US09375385B2

公开(公告)日：2016-06-28

申请号：US14135735

申请日：2013-12-20

Applicant: Becton Dickinson France

Inventor： Tracy Ray Hottovy ,  Eric Schiller

IPC: B67D7/60 ,  A61J1/06 ,  A61M5/145 ,  A61M5/20 ,  A61M5/31 ,  A61M5/315 ,  A61J1/14 ,  A61M5/48 ,  A61M5/50

CPC classification number: A61J1/062 ,  A61J1/14 ,  A61M5/14526 ,  A61M5/2053 ,  A61M5/3129 ,  A61M5/3137 ,  A61M5/31511 ,  A61M5/486 ,  A61M5/50 ,  A61M2005/3123 ,  A61M2005/3125 ,  A61M2005/3128 ,  A61M2005/3142 ,  A61M2005/31518

Abstract: A pre-filled vial assembly adapted for dispensing and delivering a fluid includes: a body member having a distal end, a proximal end, and a sidewall extending therebetween defining an interior; and a transitionable stopper disposed within the interior of the body member. At least a portion of the body member is engageable with a source of air or fluid for advancing the transitionable stopper from an initial position to an activated position in which at least a portion of a fluid contained within the interior of the body member is advanced therefrom.

公开(公告)号：US20160100875A1

公开(公告)日：2016-04-14

申请号：US14969956

申请日：2015-12-15

Applicant: TECRES S.p.A.

Inventor： Giovanni FACCIOLI ,  Renzo SOFFIATTI

IPC: A61B17/88 ,  B01F7/00 ,  B01F3/12 ,  B01F15/02 ,  A61J1/20 ,  A61J1/06

CPC classification number: A61B17/8825 ,  A61B17/8822 ,  A61B17/8827 ,  A61B2017/8838 ,  A61J1/062 ,  A61J1/2003 ,  B01F3/12 ,  B01F7/0025 ,  B01F11/0054 ,  B01F13/0023 ,  B01F15/00506 ,  B01F15/0206 ,  B01F15/0278 ,  B01F15/0279

Abstract: A device to prepare and administer a two-component mixture, including a first chamber in which a container is housed that is hermetically closed for a liquid component, a second chamber containing a powdered component, an opening of the container of the liquid component, a mixing member placed in the second chamber for preparing the mixture and a piston able to move in the second chamber to dispense the mixture. The mixing member includes a stem, passing through an opening for dispensing the mixture in the second chamber, having an outer end equipped with a handle and an inner end provided with a mixing blade connected to the inner end with a releasable connection.

Abstract translation: 一种用于制备和施用双组分混合物的装置，包括容纳容器的第一室，其中液体组分气密地封闭，第二室含有粉末组分，液体组分的容器的开口， 放置在第二室中用于制备混合物的混合构件和能够在第二室中移动以分配混合物的活塞。 混合构件包括杆，穿过用于分配第二室中的混合物的开口，具有配备有把手的外端，以及设置有连接到具有可释放连接的内端的混合叶片的内端。

公开(公告)号：US09247979B2

公开(公告)日：2016-02-02

申请号：US13122129

申请日：2010-01-25

Applicant: Giovanni Faccioli ,  Renzo Soffiatti

Inventor： Giovanni Faccioli ,  Renzo Soffiatti

IPC: B01F13/00 ,  A61B17/88 ,  B01F11/00 ,  B01F15/00 ,  B01F15/02

CPC classification number: A61B17/8825 ,  A61B17/8822 ,  A61B17/8827 ,  A61B2017/8838 ,  A61J1/062 ,  A61J1/2003 ,  B01F3/12 ,  B01F7/0025 ,  B01F11/0054 ,  B01F13/0023 ,  B01F15/00506 ,  B01F15/0206 ,  B01F15/0278 ,  B01F15/0279

Abstract: A device to prepare and administer a two-component mixture, including a first chamber in which a container is housed that is hermetically closed for a liquid component, a second chamber containing a powdered component, an opening of the container of the liquid component, a mixing member placed in the second chamber for preparing the mixture and a piston able to move in the second chamber to dispense the mixture. The mixing member includes a stem, passing through an opening for dispensing the mixture in the second chamber, having an outer end equipped with a handle and an inner end provided with a mixing blade connected to the inner end with a releasable connection.

Abstract translation: 一种用于制备和施用双组分混合物的装置，包括容纳容器的第一室，其中液体组分气密地封闭，第二室含有粉末组分，液体组分的容器的开口， 放置在第二室中用于制备混合物的混合构件和能够在第二室中移动以分配混合物的活塞。 混合构件包括杆，穿过用于分配第二室中的混合物的开口，具有配备有把手的外端，以及设置有连接到具有可释放连接的内端的混合叶片的内端。

公开(公告)号：US09238543B2

公开(公告)日：2016-01-19

申请号：US13969679

申请日：2013-08-19

Applicant: Astrium GmbH

Inventor： Peter Kern ,  Jessica Janson ,  Crispin Szydzik

IPC: B67D7/70 ,  B65D83/00 ,  A61J1/06 ,  B65D25/04 ,  B65D81/32 ,  B65B29/10

CPC classification number: B65D83/0005 ,  A61J1/062 ,  B65B29/10 ,  B65D25/04 ,  B65D81/325 ,  B65D83/0033

Abstract: The invention relates to a container, particularly in syringe form, for an at least substantially separate storage and release of substances, in particular for storage and release in outer space, with an outflow opening, a storage chamber for the storage of the substances, with at least one slideable separator element which divides the storage chamber into sub-chambers, and with at least one shaped overflow channel which is provided for transporting substances from a sub-chamber into a sub-chamber which is arranged forward as seen in the direction of the outflow opening, and/or into the outflow opening. It is proposed that the overflow channel and the separator element are designed for an at least substantially sequential release of substances and/or for washing-out a stored solid by a liquid.

Abstract translation: 本发明涉及一种容器，特别是注射器形式，用于至少基本上分开地存储和释放物质，特别是用于在外部空间中储存和释放的容器，其具有流出开口，用于存储物质的储存室， 至少一个可分离的分离器元件，其将储存室分成子室，并具有至少一个形状的溢流通道，该溢流通道用于将物质从子室输送到子室中，所述子室沿着 流出口和/或流入口。 建议溢流通道和分离器元件设计用于物质的至少基本上顺序的释放和/或用于通过液体洗出储存的固体。

公开(公告)号：US09173728B2

公开(公告)日：2015-11-03

申请号：US13765542

申请日：2013-02-12

Applicant: Merial Limited

Inventor： Patrice Wurtz

IPC: A61J1/00 ,  B65D1/36 ,  B65D35/22 ,  A61D7/00 ,  A61J1/06 ,  B65D81/32 ,  B65D75/36 ,  B65D75/32 ,  B65D75/34

CPC classification number: A61D7/00 ,  A61J1/062 ,  A61J1/065 ,  A61J1/067 ,  B65D75/323 ,  B65D75/327 ,  B65D75/34 ,  B65D75/367 ,  B65D75/368 ,  B65D81/3261 ,  B65D81/3277

Abstract: Disclosed herein are dual-cavity containers comprising, among other things, a divider wall having a first surface and a second surface opposite the first surface; a first cavity defined by a first wall coupled to the first surface of the divider wall, the first wall having an indenture shaped to conform to a thumb or finger; and a second cavity defined by a second wall and the second surface of the divider wall; the second wall having an indenture shaped to conform to a thumb or finger; and an opening mechanism.

Abstract translation: 本文公开了双腔容器，其特别包括具有第一表面和与第一表面相对的第二表面的分隔壁; 第一腔，其由耦合到所述分隔壁的第一表面的第一壁限定，所述第一壁具有成形为符合拇指或手指的压痕; 以及由所述分隔壁的第二壁和所述第二表面限定的第二腔; 所述第二壁具有成形为符合拇指或手指的压痕; 和打开机制。

公开(公告)号：US09072845B2

公开(公告)日：2015-07-07

申请号：US13642080

申请日：2011-04-21

Applicant: John Hiles

Inventor： John Hiles

IPC: A61M5/00 ,  A61M5/50 ,  A61M5/24 ,  A61J1/06 ,  A61M5/31 ,  A61M5/315

CPC classification number: A61M5/5086 ,  A61J1/062 ,  A61J2205/40 ,  A61M5/24 ,  A61M5/3134 ,  A61M5/31551 ,  A61M5/3158 ,  A61M2005/2407 ,  A61M2205/6045 ,  A61M2205/6081

Abstract: A keying insert for use with a cartridge assembly containing a fluid. The insert comprises a main body defining a bore that extends from a proximal end to a distal end of the main body and allows the fluid to dispense from the distal end of the cartridge through a septum. The main body includes a septum for sealing the fluid within the cartridge and a coding feature that is keyed to a cartridge holder or other dispense interface.

Abstract translation: 用于与包含流体的盒组件一起使用的键合插入件。 插入件包括限定从主体的近端延伸到远端的孔的主体，并允许流体通过隔膜从药筒的远端分配。 主体包括用于密封墨盒内的流体的隔膜和与墨盒保持器或其他分配界面键合的编码特征。