公开(公告)号：US06500879B1

公开(公告)日：2002-12-31

申请号：US08259833

申请日：1994-06-15

Applicant: Chin-Teh Huang ,  Kewang Lu ,  Mingxin Fan ,  Paul Hammesfahr

Inventor： Chin-Teh Huang ,  Kewang Lu ,  Mingxin Fan ,  Paul Hammesfahr

IPC: A61K6083

CPC classification number: C07C69/92 ,  A61C5/66 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/083 ,  A61K6/0835 ,  C08L33/00 ,  C08L43/02

Abstract: The invention provides dental cement compositions and methods of using them for binding hard tooth material, metal and ceramic. The cement compositions include shelf stable complexes of ethylenically unsaturated monomers reacted with cations. The cements have superior adhesion to tooth without separately acid etching dentin or enamel. Compositions of are useful as dental luting cements, liners, pit and fissure seal bases and restoratives.

Abstract translation: 本发明提供了牙科用水泥组合物及其用于结合硬质牙科材料，金属和陶瓷的方法。 水泥组合物包括与阳离子反应的烯属不饱和单体的稳定的络合物。 水泥具有优异的牙齿附着力，无需单独酸蚀牙本质或牙釉质。 作为牙科用水泥，衬垫，坑和裂缝密封基座和修复体的组合物是有用的。

公开(公告)号：US5767150A

公开(公告)日：1998-06-16

申请号：US831677

申请日：1997-04-10

Applicant: Mingxin Fan ,  Gary W. Ceska ,  James Horgan ,  Henri Strub

Inventor： Mingxin Fan ,  Gary W. Ceska ,  James Horgan ,  Henri Strub

IPC: C07D301/12 ,  C07D303/16 ,  C07D303/40 ,  C08G59/24 ,  C08G59/32 ,  A61K31/335 ,  C07D303/00

CPC classification number: C08G59/24 ,  C07D301/12 ,  C07D303/16 ,  C07D303/40 ,  C08G59/3218

Abstract: Compounds having the formula ##STR1## wherein X is selected from O, (CH.sub.2).sub.m O, S, (CH.sub.2).sub.m S, NH, (CH.sub.2).sub.m NH, COO.sup.-, (CH.sub.2).sub.m COO.sup.-, .sup.- OOC and .sup.- OOC (CH.sub.2).sub.m ; m is 1 to 6; n is 1 to 100; R.sub.1 is (C.sub.1 -C.sub.20) ester; and A is a saturated organic linking group selected from residues of polyol, polythiol, polyamine, and polyacid, are prepared by reacting compounds according to formula II ##STR2## with hydrogen peroxide in the presence of (a) tungstic acid or its metal salts, (b) phosphoric acid or its metal salts, and (c) at least one phase transfer catalyst.

Abstract translation: 具有式（I）的化合物其中X选自O，（CH 2）m O，S，（CH 2）m S，NH，（CH 2）m NH，COO-，（CH 2）m COO-， - OOC和 -OOC（CH 2）m; m为1〜6; n为1〜100; R1是（C1-C20）酯; 并且A是选自多元醇，多硫醇，多胺和多元酸的残基的饱和有机连接基团，其通过使式II（II）的化合物与（a）钨酸或其 金属盐，（b）磷酸或其金属盐，和（c）至少一种相转移催化剂。

公开(公告)号：US06559260B1

公开(公告)日：2003-05-06

申请号：US09535176

申请日：2000-03-27

Applicant: Mingxin Fan ,  Gary W. Ceska ,  James Horgan

Inventor： Mingxin Fan ,  Gary W. Ceska ,  James Horgan

IPC: C08L7516

CPC classification number: C09D175/16 ,  C08G18/6715

Abstract: The present invention is for a new class of allyl urethane resin which can be cured with peroxide at high temperature alone or in combination with some accelerators. These allyl urethane resins can be sued alone or in combination with other free radically polymerizable materials such as allyl monomers and ligomers or (meth)acrylate monomers and oligomers. These new allyl urethane resins contain at least two allyl functional groups.

Abstract translation: 本发明是一种新的烯丙基聚氨酯树脂，其可以单独或与一些加速剂组合使用，可以在高温下用过氧化物固化。 这些烯丙基聚氨酯树脂可以单独或与其它可自由基聚合的材料如烯丙基单体和连接体或（甲基）丙烯酸酯单体和低聚物组合起来。 这些新的烯丙基聚氨酯树脂含有至少两个烯丙基官能团。

公开(公告)号：US06124418A

公开(公告)日：2000-09-26

申请号：US195897

申请日：1994-02-14

Applicant: James Vincent Crivello ,  Mingxin Fan

Inventor： James Vincent Crivello ,  Mingxin Fan

IPC: C07F7/08 ,  C07F7/18 ,  C08G77/38 ,  C08G77/06 ,  C08G77/08

CPC classification number: C07F7/0829 ,  C07F7/0879 ,  C07F7/1876 ,  C08G77/38

Abstract: The invention provides a method for making a curable epoxysilicone composition through the hydrosilation reaction between an ethylenically unsaturated epoxide and an SiH-containing silicone to produce an epoxysilicone product, and catalyzed by a quaternary ammonium, phosphonium or arsonium hexahaloplatinate which does not promote the oxirane ring-opening reaction of either the ethylenically unsaturated epoxide starting material or the epoxysilicone product. The invention also provides for a curable epoxysilicone composition made by the above method.

Abstract translation: 本发明提供一种通过烯键式不饱和环氧化物和含SiH的硅氧烷之间的硅氢化反应制备可固化环氧硅氧烷组合物以制备环氧硅氧烷产物的方法，并且通过不促进环氧乙烷环的季铵，鏻或六卤化钌催化 烯键式不饱和环氧化物起始材料或环氧硅氧烷产物的开环反应。 本发明还提供了通过上述方法制备的可固化环氧硅氧烷组合物。

公开(公告)号：US6084111A

公开(公告)日：2000-07-04

申请号：US62593

申请日：1998-04-17

Applicant: Mingxin Fan ,  Gary W. Ceska ,  James Horgan ,  Henri Strub

Inventor： Mingxin Fan ,  Gary W. Ceska ,  James Horgan ,  Henri Strub

IPC: C07D301/12 ,  C07D303/16 ,  C07D303/40 ,  C08G59/24 ,  C08G59/32 ,  C07D303/00

CPC classification number: C08G59/24 ,  C07D301/12 ,  C07D303/16 ,  C07D303/40 ,  C08G59/3218

Abstract: Compounds having the formula ##STR1## wherein X is selected from O, (CH.sub.2).sub.m O, S, (CH.sub.2).sub.m S, NH, (CH.sub.2).sub.m NH, COO.sup.-, (CH.sub.2).sub.m COO.sup.-, .sup.- OOC and .sup.- OOC (CH.sub.2).sub.m ;m is 1 to 6;n is 1 to 100;R.sub.1 is selected from H, (C.sub.1 -C.sub.20) alkyl, (C.sub.1 -C.sub.20) alkoxy and (C.sub.1 -C.sub.20) ester; andA is a saturated organic linking group selected from residues of polyol, polythiol, polyamine, and polyacid, are prepared by reacting compounds according to formula II ##STR2## with hydrogen peroxide in the presence of (a) tungstic acid or its metal salts, (b) phosphoric acid or its metal salts, and (c) at least one phase transfer catalyst.

Abstract translation: 具有下式的化合物其中X选自O，（CH 2）m O，S，（CH 2）m S，NH，（CH 2）m NH，COO-，（CH 2）m COO-， - OOC和-OOC（CH 2）m; m为1〜6; n为1〜100; R1选自H，（C1-C20）烷基，（C1-C20）烷氧基和（C1-C20）酯; （a）钨酸或其金属盐的存在下，通过使根据式II的化合物与过氧化氢反应制备A是选自多元醇，多硫醇，多胺和多元酸的残基的饱和有机连接基团，（b） 磷酸或其金属盐，以及（c）至少一种相转移催化剂。

公开(公告)号：US5763629A

公开(公告)日：1998-06-09

申请号：US772979

申请日：1996-12-23

Applicant: Mingxin Fan ,  Gary W. Ceska ,  James Horgan ,  Thomas W. Hazell

Inventor： Mingxin Fan ,  Gary W. Ceska ,  James Horgan ,  Thomas W. Hazell

IPC: C07D303/16 ,  C08F20/32 ,  C08G65/14 ,  C08L71/02 ,  C07D301/12

CPC classification number: C08G65/14 ,  C07D303/16 ,  C08F20/32 ,  C08L71/02

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 32 H, CH.sub.3 ; R.sub.2 =H, (C.sub.1 -C.sub.6)alkyl; and x=1-20; and process for preparing such compounds by reacting a compound of the formula ##STR2## with hydrogen peroxide in the presence of (a) tungstic acid or its metal salts, (b) phosphoric acid or its metal salts, and (c) at least one phase transfer catalyst.

Abstract translation: 式（I）的化合物其中R 13 2 H，CH 3; R2 = H，（C1-C6）烷基; 和x = 1-20; 和（a）钨酸或其金属盐，（b）磷酸或其金属盐的存在下，使式（II）化合物与过氧化氢反应制备此类化合物的方法，和（c） 至少一种相转移催化剂。

公开(公告)号：US06391940B1

公开(公告)日：2002-05-21

申请号：US09342825

申请日：1999-06-29

Applicant: Gordon Brian Blackwell ,  Kewang Lu ,  Chin-Teh Huang ,  Mingxin Fan ,  Paul D. Hammesfahr ,  Xiuling Wang ,  Junjie Sang

Inventor： Gordon Brian Blackwell ,  Kewang Lu ,  Chin-Teh Huang ,  Mingxin Fan ,  Paul D. Hammesfahr ,  Xiuling Wang ,  Junjie Sang

IPC: C08K549

CPC classification number: C07C69/92 ,  A61C5/66 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0835 ,  C08L33/00

Abstract: A preferred embodiment of the invention provides a composition and method of treating dental metal. The composition includes a polymerizable aryl compound having at least one carboxylic acid group and at least one polymerizable group, and a polymerizable compound having at least one polymerizable group and at least one phosphorous containing group. A preferred composition includes at least 50 percent by weight of a volatile organic solvent, at least 15 percent by weight of one or more polymerizable acrylate compounds and an effective amount of a photoinitiator. At least a portion of the polymerizable compounds are multifunctional polymerizable compounds having at least three acrylate moieties. The polymerizable compounds are substantially soluble in the solvent. The composition is adapted to form a polymeric material which is adapted to adhere to metal and ceramics and to dentin. Compositions of the invention have superior adhesion to dental metals and tooth without separately acid etching dentin or enamel. Compositions are useful as dental priming adhesives, luting cements, liners, pit and fissure sealants, bases and restoratives.

Abstract translation: 本发明的优选实施方案提供了治疗牙科金属的组合物和方法。 该组合物包括具有至少一个羧酸基团和至少一个可聚合基团的可聚合芳基化合物和具有至少一个可聚合基团和至少一个含磷基团的可聚合化合物。 优选的组合物包含至少50重量％的挥发性有机溶剂，至少15重量％的一种或多种可聚合丙烯酸酯化合物和有效量的光引发剂。 至少一部分可聚合化合物是具有至少三个丙烯酸酯部分的多官能可聚合化合物。 可聚合化合物基本上可溶于溶剂。 该组合物适于形成适于粘附到金属和陶瓷以及牙质的聚合材料。 本发明的组合物具有优异的与牙科金属和牙齿的粘合性，而无需单独酸蚀牙本质或牙釉质。 组合物可用作牙科起始粘合剂，粘合剂，衬垫，凹坑和裂缝密封剂，基底和修复剂。

公开(公告)号：US06242506B1

公开(公告)日：2001-06-05

申请号：US09120508

申请日：1998-07-22

Applicant: Mingxin Fan ,  Gary W. Ceska ,  James Horgan

Inventor： Mingxin Fan ,  Gary W. Ceska ,  James Horgan

IPC: C08G1867

CPC classification number: C08G18/672 ,  C08G18/42 ,  C08G18/48

Abstract: Radiation curable acrylic compositions are improved with regard to flame resistance by incorporating a reactive compound which is the reaction product of tetrabromophthalic anhydride or acid and a (meth)acrylic compound.

Abstract translation: 通过加入作为四溴邻苯二甲酸酐或酸与（甲基）丙烯酸类化合物的反应产物的反应性化合物，可辐射固化丙烯酸组合物在阻燃性方面得到改善。

公开(公告)号：US06191190B1

公开(公告)日：2001-02-20

申请号：US09080781

申请日：1998-05-18

Applicant: Gordon Brian Blackwell ,  Kewang Lu ,  Chin-Teh Huang ,  Mingxin Fan ,  Paul D. Hammesfahr

Inventor： Gordon Brian Blackwell ,  Kewang Lu ,  Chin-Teh Huang ,  Mingxin Fan ,  Paul D. Hammesfahr

IPC: C08K549

CPC classification number: C07C69/92 ,  A61C5/66 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/083 ,  A61K6/0835 ,  C08L33/00 ,  C08L43/02

Abstract: A composition and method of treating a dental tooth. The composition includes a polymerizable aryl compound having at least one carboxylic acid group and at least one polymerizable group, and a polymerizable compound having at least one polymerizable group and at least one phosphorous containing group. A preferred composition includes at least 50 percent by weight of a volatile organic solvent, at least 15 percent by weight of one or more polymerizable acrylate compounds and an effective amount of a photoinitiator. At least a portion of the polymerizable compounds are multifunctional polymerizable compounds having at least three acrylate moieties. The polymerizable compounds are substantially soluble in the solvent. The composition is adapted to form a polymeric material which is adapted to adhere to dentin. Compositions of the invention have superior adhesion to tooth without separately acid etching dentin or enamel. Compositions of are useful as dental priming adhesives, luting cements, liners, pit and fissure sealants, bases and restoratives.

Abstract translation: 治疗牙齿的组合物和方法。 该组合物包括具有至少一个羧酸基团和至少一个可聚合基团的可聚合芳基化合物和具有至少一个可聚合基团和至少一个含磷基团的可聚合化合物。 优选的组合物包含至少50重量％的挥发性有机溶剂，至少15重量％的一种或多种可聚合丙烯酸酯化合物和有效量的光引发剂。 至少一部分可聚合化合物是具有至少三个丙烯酸酯部分的多官能可聚合化合物。 可聚合化合物基本上可溶于溶剂。 该组合物适于形成适于粘附于牙本质的聚合物材料。 本发明的组合物在没有单独酸蚀牙本质或牙釉质的情况下具有优异的牙齿附着性。 组合物可用作牙科起始粘合剂，粘结剂，衬垫，凹坑和裂缝密封剂，基底和修复剂。

公开(公告)号：US5900472A

公开(公告)日：1999-05-04

申请号：US772432

申请日：1996-12-23

Applicant: Mingxin Fan ,  Gary W. Ceska ,  James Horgan

Inventor： Mingxin Fan ,  Gary W. Ceska ,  James Horgan

IPC: C07C67/08 ,  C07C69/76 ,  C07C69/94 ,  C07C323/62 ,  C08F2/50 ,  C08F22/10 ,  C08F220/30 ,  C08G6/00 ,  C08G10/00 ,  C08G14/00

CPC classification number: C08F22/105 ,  C07C69/76 ,  Y10T428/31627 ,  Y10T428/31649

Abstract: Copolymerizable benzophenone photoinitiators of the formula I ##STR1## wherein 1, k=0, 1, 2.R.sub.1 =divalent organic group having 1 to 25 carbon atoms;R.sub.2 =H or methyl; andR.sub.3, R.sub.4 =organic group having 1 to 25 carbon atoms.X, Y=hydrogen, halogen or (C.sub.1 -C.sub.25) groups containing N, S, and/or O;and method of making the photoinitiators.The photoinitiators overcome the leaching problem with prior photoinitiators in radiation curable polymer applications. Radiation curable polymers, cured polymers, and coated articles are also disclosed.

Abstract translation: 式I的可共聚二苯甲酮光引发剂，其中1，k = 0,1,2。R1 =具有1至25个碳原子的二价有机基团; R2 = H或甲基; R3，R4 =碳原子数为1〜25的有机基团。 X，Y =氢，卤素或含有N，S和/或O的（C1-C25）基团; 以及制备光引发剂的方法。 光引发剂克服了可辐射固化聚合物应用中先前光引发剂的浸出问题。 还公开了可辐射固化聚合物，固化聚合物和涂覆制品。