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    SOLID-PHASE SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS AND OLIGONUCLEOTIDE SYNTHESIS METHOD
    6.
    发明申请
    SOLID-PHASE SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS AND OLIGONUCLEOTIDE SYNTHESIS METHOD 有权
    寡核苷酸合成和寡核苷酸合成方法的固相支持

    公开(公告)号：US20130317206A1

    公开(公告)日：2013-11-28

    申请号：US13901266

    申请日：2013-05-23

    Applicant: Nitto Denko Corporation

    Inventor： Eri MAETA ,  Kenjiro MORI ,  Kazuya MIWA

    IPC: C08F22/10 ,  C07H21/04

    CPC classification number: C08F22/105 ,  C07B35/04 ,  C07B61/02 ,  C07H19/04 ,  C07H19/06 ,  C07H19/16 ,  C07H21/04 ,  C08F2/18 ,  C08F8/12 ,  C08F12/22 ,  C08F212/08 ,  C08F212/36 ,  C08F2800/20 ,  C08F2220/286 ,  C08F212/14

    Abstract: The present invention provides a solid-phase support for oligonucleotide synthesis for synthesizing long chain oligonucleotide, RNA oligonucleotide and modified oligonucleotide at high synthetic quantity and high purity with a low loading amount of a linker. Provided is a solid-phase support for oligonucleotide synthesis comprising a porous resin bead having a monovinyl monomer unit, a crosslinkable vinyl monomer unit and a polyethylene glycol unit and a cleavable linker loaded on its surface, the porous resin bead having a group capable of binding to a carboxy group by a dehydration condensation reaction on its surface, the cleavable linker having a carboxy group, wherein the carboxy group of the cleavable linker is bound to the group capable of binding to a carboxy group, by a dehydration condensation reaction, and a loading amount of the cleavable linker is 1 to 80 μmol/g relative to the weight of the porous resin bead.

    Abstract translation: 本发明提供了一种用于合成高链寡核苷酸，RNA寡核苷酸和高合成量和高纯度的具有低负载量的接头的高纯度的修饰的寡核苷酸的寡核苷酸合成的固相支持物。 提供了一种用于寡核苷酸合成的固相载体，其包含具有单乙烯基单体单元，可交联乙烯基单体单元和聚乙二醇单元的多孔树脂珠粒和其表面上负载的可切割连接物，所述多孔树脂珠粒具有能够结合的基团 通过其表面上的脱水缩合反应与羧基反应，可切割接头具有羧基，其中可切割接头的羧基通过脱水缩合反应与能结合羧基的基团结合，并且 可切割接头的负载量相对于多孔树脂珠的重量为1〜80μmol/ g。

    COMPOSITION FOR FORMING LIQUID CRYSTAL LAYER, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY DEVICE
    7.
    发明申请
    COMPOSITION FOR FORMING LIQUID CRYSTAL LAYER, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY DEVICE 审中-公开

    公开(公告)号：US20130135570A1

    公开(公告)日：2013-05-30

    申请号：US13814025

    申请日：2011-07-27

    Applicant: Masanobu Mizusaki ,  Satoshi Enomoto ,  Yuki Hara

    Inventor： Masanobu Mizusaki ,  Satoshi Enomoto ,  Yuki Hara

    IPC: G02F1/1337

    CPC classification number: G02F1/133711 ,  C08F20/20 ,  C08F22/105 ,  C09K19/32 ,  C09K2019/0448 ,  G02F1/133723 ,  G02F2202/023

    Abstract: The present invention provides a composition for forming a liquid crystal layer from which a liquid crystal display device hardly generating image sticking can be obtained. The composition for forming a liquid crystal layer according to the present invention contains a liquid crystal material and one or two or more monomers, wherein at least one of the monomers is a phenanthrene derivative represented by the following chemical formula (1): the following chemical formula (2): or the following chemical formula (3): wherein R1 and R2 are identical or different, and each denote an -Sp-P group, a hydrogen atom, a halogen atom, a —CN group, a —NO2 group, a —NCO group, a —NCS group, an —OCN group, a —SCN group, a —SF5 group, or a straight-chain or branched-chain alkyl group having 1 to 12 carbon atoms; at least one of R1 and R2 denotes an -Sp-P group; P denotes a polymerizable group; Sp denotes a straight-chain, branched-chain or cyclic alkylene group or alkyleneoxy group having 1 to 6 carbon atoms, or a direct bond of both groups interposing Sp; a hydrogen atom which R1 and R2 have may be replaced by a fluorine atom or a chlorine atom; and a —CH2— group which R1 and R2 have, unless oxygen atoms, sulfur atoms and nitrogen atoms are mutually adjacent, may be substituted with an —O— group, a —S— group, a —NH— group, a —CO— group, a —COO— group, a —OCO— group, an —O—COO— group, a —OCH2— group, a —CH2O— group, a —SCH2— group, a —CH2S— group, a —N(CH3)— group, a —N(C2H5)— group, a —N(C3H7)— group, a —N(C4H5)— group, a —CF2O— group, a —OCF2— group, a —CF2S— group, a —SCF2— group, a —N(CF3)— group, a —CH2CH2— group, a —CF2CH2— group, a —CH2CF2— group, a —CF2CF2— group, a —CH═CH— group, a —CF═CF— group, a —C≡C— group, a —CH═CH—COO— group, or a —OCO—CH═CH— group.

    Method of making triglyceride macromonomers
    8.
    发明授权
    Method of making triglyceride macromonomers 有权
    制备甘油三酯大分子单体的方法

    公开(公告)号：US08362176B2

    公开(公告)日：2013-01-29

    申请号：US12808999

    申请日：2008-12-16

    Applicant: Jeff T. Carter ,  Steve Quinn

    Inventor： Jeff T. Carter ,  Steve Quinn

    IPC: C08F22/10 ,  C07C51/353

    CPC classification number: C11C3/00 ,  C07C67/08 ,  C07C69/75 ,  C07C2601/14 ,  C08F22/105 ,  C11C3/04

    Abstract: A process of making a polymerisable ethylenically unsaturated macromonomer from an unsaturated non-mineral oil, the oil being a mixture of triglycerides, some of which comprise at least one fatty acid having at least two non-conjugated unsaturated bonds at least one of which is ethylenically unsaturated, the process comprising the steps of: i) conjugating the non-conjugated unsaturated bonds, ii) reacting the reaction product of step (i) with an enophile having an acid, ester or anhydride moiety to form an adduct, iii) reacting the adduct with an ethylencially unsaturated monomer having a moiety reactive with the acid, ester or anhydride moiety of the enophile to form an intermediate iv) reacting the intermediate of step (iii) with a chain extender having at least two moieties reactive with the acid, ester or anhydride moiety of the enophile to form the macromonomer, where the oil has an iodine value of from 110 to 180 g of iodine per 100 g of oil.

    Abstract translation: 从不饱和非矿物油制备可聚合的烯键式不饱和大单体的方法，该油是甘油三酯的混合物，其中一些包含至少一种具有至少两个非共轭不饱和键的脂肪酸，其中至少一种是烯属的 所述方法包括以下步骤：i）缀合非共轭不饱和键，ii）使步骤（i）的反应产物与具有酸，酯或酸酐部分的亲脂子反应以形成加合物，iii）使 与具有与亲合子的酸，酯或酸酐部分反应的部分的乙烯不饱和单体加成形成中间体iv）使步骤（iii）的中间体与具有至少两个与酸酯反应的部分的扩链剂反应 或亲油基团的酸酐部分形成大分子单体，其中油的每100克油的碘值为110至180克碘。

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