公开(公告)号：US4937526A

公开(公告)日：1990-06-26

申请号：US365632

申请日：1989-06-13

申请人： Richard L. Ehman ,  Joel P. Felmlee

发明人： Richard L. Ehman ,  Joel P. Felmlee

IPC分类号： A61B5/055 ,  G01R33/48 ,  G01R33/54 ,  G01R33/567

CPC分类号： G01R33/5676

摘要： An NMR data set which is acquired with applied phase encoding and read-out gradients is corrected to reduce motion artifacts and increase image sharpness. The acquired NMR data set is examined to detect bulk displacements of the object being imaged and phase displacements caused by motion. This information is employed to produce correction operators which are applied to the NMR image data set. One or more navigator signals may also be acquired during the scan to produce an NMR data set from which the corrective operators can more readily be derived.

摘要翻译： 校正采用施加的相位编码和读出梯度获得的NMR数据集，以减少运动伪影并增加图像清晰度。 检查获取的NMR数据集以检测被成像物体的体积位移和由运动引起的相位位移。 该信息用于产生应用于NMR图像数据集的校正算子。 也可以在扫描期间获取一个或多个导航信号以产生NMR数据集，校正操作者可从该数据集更容易地导出。

公开(公告)号：US09519037B2

公开(公告)日：2016-12-13

申请号：US13674654

申请日：2012-11-12

申请人： Joel P. Felmlee

发明人： Joel P. Felmlee

IPC分类号： G01V3/00 ,  G01R33/34 ,  G01R33/341 ,  G01R33/3415

CPC分类号： G01R33/34092 ,  G01R33/34007 ,  G01R33/341 ,  G01R33/3415

摘要： A magnetic resonance imaging receiver coil provides for high SNR and high uniformity over a range of loading conditions with layers, or stacks, of independent conductive elements. The plurality of layers preload the receiver coil reducing the circuit variation as the subject coupling and loading varies. The preload is such that coil performance, or SNR, is maintained over a large range of impedance variation. This configuration is designed to exceed the performance of single trace coils over a range of impedance consistent with variations associated with different subjects, and may also incorporate coils of different resonance frequencies.

摘要翻译： 磁共振成像接收器线圈在具有独立导电元件的层或堆叠的一系列负载条件下提供高SNR和高均匀性。 当主体耦合和负载变化时，多个层预加载接收器线圈减小电路变化。 预加载使得线圈性能或SNR保持在较大的阻抗变化范围内。 该配置被设计为超过了与不同主题相关联的变化的阻抗范围内的单个迹线线圈的性能，并且还可以包括不同谐振频率的线圈。

公开(公告)号：US09134393B2

公开(公告)日：2015-09-15

申请号：US14049632

申请日：2013-10-09

申请人： Joel P. Felmlee ,  Richard L. Ehman ,  Matthew C. Murphy

发明人： Joel P. Felmlee ,  Richard L. Ehman ,  Matthew C. Murphy

IPC分类号： A61B5/055 ,  G01R33/48 ,  A61B8/08 ,  A61B5/00 ,  G01R33/563

CPC分类号： G01R33/4814 ,  A61B5/0035 ,  A61B5/055 ,  A61B5/725 ,  A61B5/7278 ,  A61B8/485 ,  G01R33/56358

摘要： A system and method for generating a magnetic resonance elastography (MRE) report includes a) acquiring MRE data from a subject including positively motion encoded medical imaging data and negatively motion encoded medical imaging data and b) deriving uncorrected difference medical imaging data from the MRE data for a given slice. The method also includes c) filtering the uncorrected difference medical imaging data to create filtered medical imaging data corrected for errors associated with phase ramps occurring during gradient switching used to derive the positively motion encoded medical imaging data and negatively motion encoded medical imaging data, d) generating a corrected difference image for the given slice from the filtered medical imaging data and the uncorrected difference medical imaging data, e) repeating steps b) through d) for each slice reflected in the MRE data, and f) generating a report of elastic properties of the subject from the corrected difference image.

摘要翻译： 用于产生磁共振弹性成像（MRE）报告的系统和方法包括：a）从主体获取MRE数据，包括正运动编码的医学成像数据和负运动编码的医学成像数据，以及b）从MRE数据导出未校正的差分医学成像数据 对于给定的切片。 该方法还包括：c）对未校正的差分医学成像数据进行滤波，以产生针对与用于导出正运动编码的医学成像数据和负运动编码的医学成像数据的梯形切换期间发生的相位斜坡相关的误差校正的滤波的医学成像数据，d） 从经滤波的医学成像数据和未校正的差分医学成像数据生成针对给定切片的校正差分图像，e）对在MRE数据中反映的每个切片重复步骤b）至d），以及f）生成弹性特性报告 从修正后的差分图像中获取。

公开(公告)号：US20130131490A1

公开(公告)日：2013-05-23

申请号：US13453070

申请日：2012-04-23

申请人： John Huston, III ,  Clifford R. Jack, JR. ,  Kevin J. Glaser ,  Armando Manduca ,  Joel P. Felmlee ,  Richard L. Ehman ,  Matthew C. Murphy

发明人： John Huston, III ,  Clifford R. Jack, JR. ,  Kevin J. Glaser ,  Armando Manduca ,  Joel P. Felmlee ,  Richard L. Ehman ,  Matthew C. Murphy

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/0042 ,  A61B5/0051 ,  A61B5/4088 ,  G01R33/56358

摘要： A system and method for analyzing a subject using a magnetic resonance imaging (MRI) system is provided. The technique includes positioning a subject within the MRI system and coupling a driver to the subject to impart vibrational energy to the subject. The technique further includes using the MRI system and in coordination with operation of the driver, acquiring medical imaging data from the subject's brain and deriving stiffness information of the subject's brain from the medical imaging data. A report, such as an image, can be provided indicating the stiffness information of the subject's brain relative to baseline stiffness information to indicate a status of the subject with respect to a neurodegenerative disease.

摘要翻译： 提供了一种使用磁共振成像（MRI）系统分析对象的系统和方法。 该技术包括将对象定位在MRI系统内并且将驾驶员与受试者联接以向对象施加振动能量。 该技术还包括使用MRI系统并与驾驶员的操作协调，从受试者的大脑获取医学成像数据，并从医学成像数据导出受检者脑部的刚度信息。 可以提供诸如图像的报告，指示受试者的脑相对于基线刚度信息的刚度信息，以指示受试者相对于神经变性疾病的状态。

公开(公告)号：US07991449B2

公开(公告)日：2011-08-02

申请号：US11407759

申请日：2006-04-20

申请人： Richard L. Ehman ,  Kiaran P. McGee ,  Brian C. Goss ,  Joel P. Felmlee

发明人： Richard L. Ehman ,  Kiaran P. McGee ,  Brian C. Goss ,  Joel P. Felmlee

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  A61B5/0051 ,  A61B5/08 ,  G01R33/56358

摘要： A noble gas is administered to a subject to fill the lungs and magnetic resonance elastography image data is acquired while vibrations are applied to the chest wall. Shear waves are established in the gas-filled lungs by the vibrations and a shear modulus image is reconstructed from the MRE image data that may be used in the diagnosis of lung disease.

摘要翻译： 向受试者施用惰性气体以填充肺，并且在振动施加到胸壁时获取磁共振弹性成像图像数据。 通过振动在气体填充的肺中建立剪切波，并且可以用于诊断肺部疾病的MRE图像数据重建剪切模量图像。

公开(公告)号：US07542793B2

公开(公告)日：2009-06-02

申请号：US10225915

申请日：2002-08-22

申请人： Tao Wu ,  Joel P. Felmlee

发明人： Tao Wu ,  Joel P. Felmlee

IPC分类号： A61B5/00

CPC分类号： G01R33/4804

摘要： An MRI system is employed to aim an ultrasonic transducer at tissues to be treated and to produce images which enable the treatment of the tissues to be monitored. A pulse sequence is used which produces both a spin-echo NMR signal and a gradient-echo NMR signal and changes in phase between these two signals is measured and used to produce a temperature map. Changes in amplitude of the spin-echo NMR signal from a reference spin-echo NMR signal is used to produce images which indicate temperature changes in both fat and water. These temperature maps may be used to aim the heat treatment device.

摘要翻译： 使用MRI系统将超声波换能器瞄准待治疗的组织，并产生能够对要监测的组织进行治疗的图像。 使用产生自旋回波NMR信号和梯度回波NMR信号的脉冲序列，并测量这两个信号之间的相位变化并用于产生温度图。 使用来自参考自旋回波NMR信号的自旋回波NMR信号的振幅的变化来产生指示脂肪和水中的温度变化的图像。 这些温度图可用于瞄准热处理装置。

公开(公告)号：US20070172029A1

公开(公告)日：2007-07-26

申请号：US11638162

申请日：2006-12-13

申请人： Joel P. Felmlee ,  Russell E. Bruhnke ,  Phillip Rossman ,  James P. Potter

发明人： Joel P. Felmlee ,  Russell E. Bruhnke ,  Phillip Rossman ,  James P. Potter

IPC分类号： H05G1/10

CPC分类号： A61B5/1135 ,  A61B5/7285 ,  A61B6/504 ,  A61B6/541

摘要： A bellows-based patient breath-hold monitoring and feedback system for use in intermittent mode CT fluoroscopy-guided biopsies of the lung or upper abdomen where respiratory motion is a problem. Breath-hold monitoring and feedback with the bellows system allows a patient to perform consistent breath-holds at a preselected level, which in turn, optimizes intermittent mode CT fluoroscopy-guided biopsies of the lung or upper abdomen by allowing target lesions to be reliably visualized.

摘要翻译： 一种基于波纹管的患者呼吸监测和反馈系统，用于间歇模式CT荧光透视引导的肺或上腹部活检，呼吸运动是一个问题。 使用波纹管系统进行呼吸保持监测和反馈允许患者以预先选择的水平执行一致的呼吸保持，这进而优化通过允许目标病变可靠地可视化来显示肺或上腹部的间歇模式CT透视图引导的活组织检查 。

公开(公告)号：US06184682B2

公开(公告)日：2001-02-06

申请号：US09290817

申请日：1999-04-13

申请人： Richard L. Ehman ,  Joel P. Felmlee ,  Armando Manduca ,  Kiaran P. McGee

发明人： Richard L. Ehman ,  Joel P. Felmlee ,  Armando Manduca ,  Kiaran P. McGee

IPC分类号： G01V300

CPC分类号： G06T5/003 ,  G06T5/10 ,  G06T5/50 ,  G06T2207/10016 ,  G06T2207/10088 ,  G06T2207/20056 ,  G06T2207/30004 ,  G06T2207/30168

摘要： Navigator echo signals are acquired during an MRI scan in which image data is acquired. The navigator echo signals are used to estimate an initial correction of the acquired image data for patient motion during the scan. The initially corrected image data is then autocorrected in an iterative process which measures image quality and makes further corrections to the image data until the measured image quality is within tolerance.

摘要翻译： 在获取图像数据的MRI扫描期间获取导航回波信号。 导航回波信号用于估计在扫描期间所获取的图像数据的患者运动的初始校正。 然后在迭代过程中自动校正最初校正的图像数据，该迭代过程测量图像质量并进一步校正图像数据，直到测量的图像质量在容差内。