公开(公告)号：US20060211582A1

公开(公告)日：2006-09-21

申请号：US11351863

申请日：2006-02-10

申请人： Arturo Valencia Sil ,  Lawrence Grab ,  Bruce Schmidt ,  David Halsrud ,  Guang-Jong Wei ,  Eric Morrison ,  Hector DiBenedetto ,  Jessica Anacker ,  Richard Johnson ,  Megan Malvey ,  Scott Bennett ,  Stefan Seemeyer

发明人： Arturo Valencia Sil ,  Lawrence Grab ,  Bruce Schmidt ,  David Halsrud ,  Guang-Jong Wei ,  Eric Morrison ,  Hector DiBenedetto ,  Jessica Anacker ,  Richard Johnson ,  Megan Malvey ,  Scott Bennett ,  Stefan Seemeyer

IPC分类号： C10M173/00

CPC分类号： C10M173/025 ,  B65G45/02 ,  C10M103/00 ,  C10M125/26 ,  C10M133/06 ,  C10M155/02 ,  C10M169/04 ,  C10M2201/02 ,  C10M2201/10 ,  C10M2201/102 ,  C10M2207/126 ,  C10M2207/289 ,  C10M2209/104 ,  C10M2215/02 ,  C10M2215/04 ,  C10M2219/044 ,  C10M2223/04 ,  C10M2229/02 ,  C10M2229/025 ,  C10M2229/041 ,  C10M2229/042 ,  C10M2229/045 ,  C10M2229/047 ,  C10M2229/051 ,  C10N2230/00 ,  C10N2230/02 ,  C10N2230/06 ,  C10N2230/40 ,  C10N2240/52 ,  C10N2250/021 ,  C10N2250/04 ,  C10N2250/121 ,  C10N2270/02 ,  C10M2215/042 ,  C10M2209/105 ,  C10M2207/122

摘要： The passage of a container along a conveyor is lubricated by applying to the container or conveyor a lubricant composition comprising a water-miscible silicone material having a silicone emulsion wherein the silicone emulsion contains less than 500 ppm of a triethanolamine salts of alkyl benzene sulfonic acid compounds.

摘要翻译： 通过向容器或输送机施加包含具有硅氧烷乳液的水混溶性硅氧烷材料的润滑剂组合物来润滑容器沿输送机的通道，其中硅氧烷乳液含有小于500ppm的烷基苯磺酸化合物的三乙醇胺盐 。

公开(公告)号：US20230149320A1

公开(公告)日：2023-05-18

申请号：US17670445

申请日：2022-02-12

申请人： Eric Morrison

发明人： Eric Morrison

IPC分类号： A61K9/51 ,  A61K9/10 ,  A61K31/352

CPC分类号： A61K9/5192 ,  A61K9/10 ,  A61K31/352 ,  B82Y5/00

摘要： The present invention provides a method of preparing a lipid nanoparticle dispersion using a twin screw extruder. The inventive lipid nanoparticle dispersion includes greater than 25% lipophilic content in the form of lipidic nanoparticles with volume average particle size less than 120 nm dispersed in a continuous aqueous matrix with greater than 0.1 percent of tetrahydrocannabinol.

公开(公告)号：US11504327B1

公开(公告)日：2022-11-22

申请号：US16748399

申请日：2020-01-21

申请人： Eric Morrison

发明人： Eric Morrison

IPC分类号： A61K9/107 ,  A61K9/00 ,  A61K31/192 ,  A61K47/26 ,  A61K47/44 ,  A61K47/34 ,  A61K47/24 ,  A61K47/14 ,  A61K47/06 ,  A61K47/08

摘要： The present invention provides a nanoparticle dispersion for topical delivery to skin of a mammal. The nanoparticle dispersion includes: one or more hydrophobic bioactive agents or one or more hydrophobic drugs; one or more surfactants; one or more water immiscible oils; and water. Methods of preparing nanoparticle dispersions by hot melt extrusion are also provided.

公开(公告)号：US11007161B1

公开(公告)日：2021-05-18

申请号：US16165904

申请日：2018-10-19

申请人： Eric Morrison

发明人： Eric Morrison

IPC分类号： A61K31/192 ,  A61K9/51 ,  A61K9/107 ,  A61K9/00 ,  B82Y5/00 ,  A61K9/127

摘要： The present invention provides nanoparticle dispersion for topical delivery to skin of a mammal. The nanoparticle dispersion includes: a sorbitan ester surfactant; one or more poly(ethoxylate) surfactants, one or more lipids; and ibuprofen. Methods of preparing various water continuous dispersion of nanoparticles are also provided.

公开(公告)号：US20160184228A1

公开(公告)日：2016-06-30

申请号：US14985570

申请日：2015-12-31

申请人： Eric Morrison

发明人： Eric Morrison

IPC分类号： A61K9/127 ,  A61K9/00 ,  A61K31/167 ,  A61K31/192 ,  A61K31/616

CPC分类号： A61K9/1272 ,  A61K9/0014 ,  A61K9/1075 ,  A61K9/127 ,  A61K31/167 ,  A61K31/192 ,  A61K31/616

摘要： The present invention provides a niosomal composition having including: one or more high Kow pharmacologically active compounds; one or more water immiscible oils; one or more low HLB surfactants; one or more polyethoxylated high HLB surfactants; water, and wherein the niosomal composition includes an external phase and a dispersed phase, the particles of the dispersed phase including an oil swollen lipid bilayer. Methods of preparing niosomal compositions by hydration of lamellar phase microemulsions and methods of using these compositions to treat various disorders in a patient in need thereof are also provided.

摘要翻译： 本发明提供一种niosomal组合物，其包含：一种或多种高Kow药理活性化合物; 一种或多种与水不混溶的油; 一种或多种低HLB表面活性剂; 一种或多种聚乙氧基化高HLB表面活性剂; 水，并且其中所述niosomal组合物包含外相和分散相，所述分散相的颗粒包括油溶性脂质双层。 还提供了通过层状相微乳液的水合制备niosomal组合物的方法和使用这些组合物治疗有此需要的患者中的各种疾病的方法。