公开(公告)号：US10684341B2

公开(公告)日：2020-06-16

申请号：US16094907

申请日：2017-04-18

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Michael Gunter Helle ,  Thomas Lindner

IPC: G01R33/563 ,  A61B5/055 ,  G01R33/483

Abstract: A method of magnetic resonance imaging (100, 200) includes acquiring (300) tagged magnetic resonance data (144) by controlling the magnetic resonance imaging system with tagging pulse sequence commands (140). The tagging pulse sequence commands include a tagging inversion pulse portion (404) for spin labeling a tagging location (122, 122′) within a subject (118). The tagging pulse sequence commands comprise a phase-contrast readout portion (406) which phase-contrast encodes in at least one direction. The control pulse sequence commands include a control inversion pulse portion (500) and the phase-contrast readout portion. A tagged magnitude image (148) is reconstructed (304) using the tagged magnetic resonance data. A control magnitude image (150) is reconstructed (306) using the control magnetic resonance data. An arterial image (152) is reconstructed (308) by subtracting the control magnitude image and the tagged magnitude image. At least one phase image (156, 158, 160) is reconstructed (312) using either the tagged magnetic resonance data and/or the control magnetic resonance data.

公开(公告)号：US10557904B2

公开(公告)日：2020-02-11

申请号：US14781596

申请日：2014-03-27

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Christian Stehning ,  Nicole Schadewaldt ,  Michael Gunter Helle ,  Steffen Renisch ,  Heinrich Schulz

IPC: G06K9/00 ,  G06T7/00 ,  G01R33/56 ,  G01R33/48 ,  A61B6/03 ,  A61N5/10 ,  G01R33/36 ,  G01R33/385 ,  G06K9/52 ,  G06K9/62 ,  G06T11/00

Abstract: A medical apparatus (300, 400, 500) includes a magnetic resonance imaging system (302) for acquiring magnetic resonance data (342) from an imaging zone (308); a processor (330) for controlling the medical apparatus; a memory (336) storing machine executable instructions (350, 352, 354, 356). Execution of the instructions causes the processor to: acquire (100, 200) the magnetic resonance data using a pulse sequence (340) which specifies an echo time greater than 400 μs; reconstruct (102, 202) a magnetic resonance image using the magnetic resonance data; generate (104, 204) a thresholded image (346) by thresholding the magnetic resonance image to emphasize bone structures and suppressing tissue structures in the magnetic resonance image; and generate (106, 206) a bone-enhanced image by applying a background removal algorithm to the thresholded image.

公开(公告)号：US11410353B2

公开(公告)日：2022-08-09

申请号：US16767613

申请日：2018-11-29

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Michael Gunter Helle ,  Thomas Lindner

IPC: G06T11/00 ,  G01R33/48 ,  G01R33/56 ,  G01R33/563 ,  G06T7/00 ,  G06T15/08

Abstract: The invention provides for a medical imaging system (100, 300) comprising a processor (106) for controlling the medical imaging system. Execution of machine executable instructions (112) causes the processor to receive (200) a static angiographic image (114) of a region of interest (322), receive (202) a time series of angiographic images (116, 116′) of the region of interest, construct (204) an image mask (118) using the static angiographic image, determine (206) a time dependent signal (120) for each voxel within the image mask using the time series of angiographic images, construct (208) a composite angiographic image by: assigning (210) a fill time (126) to each voxel within the image mask using an extremum (124) of the time dependent signal if the extremum deviates from an average of the time dependent signal more than a predetermined threshold, and identifying (212) voxels within the image mask as being unfilled voxels.

公开(公告)号：US11333732B2

公开(公告)日：2022-05-17

申请号：US17047749

申请日：2019-04-17

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Karsten Sommer ,  Axel Saalbach ,  Michael Gunter Helle ,  Steffen Weiss ,  Christophe Michael Jean Schulke

IPC: G01V3/00 ,  G01R33/54 ,  A61B5/055 ,  G01R33/56 ,  G01R33/565 ,  A61B5/00

Abstract: The invention provides for a magnetic resonance imaging system (100, 300). The execution of machine executable instructions causes a processor (130) controlling the magnetic resonance imaging system to control (200) the magnetic resonance imaging system to acquire the magnetic resonance imaging data (144) using pulse sequence commands (142) and reconstruct (202) a magnetic resonance image (148). Execution of the machine executable instructions causes the processor to receive (204) a list of suggested pulse sequence command changes (152) by inputting the magnetic resonance image and image metadata (150) into an MRI artifact detection module (146, 146′, 146″). The MRI artifact detection module comprises at least one neural network, which has been trained using images from failed magnetic resonance imaging protocols and/or magnetic resonance data extracted from the magnetic resonance imaging protocols labeled as failed accessed from a log file (312) which logs the execution of previous magnetic resonance imaging protocols. Execution of the machine executable instructions further causes the processor to receive (206) a selection of a chosen pulse sequence command change (158) from the list of suggested pulse sequence command changes. Execution of the machine executable instructions further causes the processor to modify (208) the pulse sequence commands using the chosen pulse sequence command change.

公开(公告)号：US11199604B2

公开(公告)日：2021-12-14

申请号：US15303758

申请日：2015-04-17

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Michael Gunter Helle ,  Matthias Johannes Paulus Van Osch

IPC: G01R33/563 ,  G01R33/483 ,  A61B5/00 ,  A61B5/026 ,  A61B5/055 ,  G01R33/54

Abstract: The present invention provides a method for magnetic resonance (MR) imaging of a subject of interest (120) using arterial spin labeling, comprising the steps of performing a labeling module (200) by applying magnetic and/or radio frequency (RF) fields to the subject of interest (120) for labeling arterial blood in at least a labeling region (144) thereof, performing a first readout module (202) to obtain first MR information of the subject of interest (120) in a region of interest (142) using first parameters, performing a second readout module (204) to obtain second MR information of the subject of interest (120) in a region of interest (142) using second parameters, and performing MR image generation of a region of interest (142) based on the first and second MR information, wherein the first and second parameters of the first and second readout module (202, 204) are chosen to be different parameters. The invention also provides a MR imaging system (110) adapted to perform the above method and a software package for upgrading a MR imaging system (110), whereby the software package contains instructions for controlling the MR imaging system (110) according to the above method.

公开(公告)号：US10955509B2

公开(公告)日：2021-03-23

申请号：US14760845

申请日：2013-12-31

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Michael Gunter Helle ,  Tim Nielsen

IPC: G01V3/00 ,  G01R33/563 ,  G01R33/54 ,  G01R33/385

Abstract: A magnetic resonance imaging (MRI) system (100, 600) that generates information indicative of a fluid flow in accordance with a pseudo-continuous arterial spin labeling (pCASL) method. The MRI system may include at least one controller (104, 610) configured to generate a pseudo-continuous arterial spin labeling (pCASL) pulse sequence (200) including at least a first gradient (GR) pulse sequence (207) having a sinusoidal waveform including a plurality of cycles, and a second radio frequency (RF) pulse sequence (205) including a half-wave rectified sinusoidal waveform having a plurality of cycles and which is synchronous with the first GR pulse sequence; label at least part of the fluid flow in a labeling region during a labeling mode using the pCASL pulse sequence; acquire label and control image information of the fluid flow at an imaging region proximal to downstream of the labeling region; and/or generate image information in accordance with a difference of the acquired label and control image information. The sinusoidal gradient waveform results in less acoustic noise during execution of the pulse sequence.

公开(公告)号：US10677871B2

公开(公告)日：2020-06-09

申请号：US16094899

申请日：2017-04-10

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Michael Gunter Helle ,  Thomas Lindner

IPC: G01R33/563

Abstract: A medical imaging system (100, 1200) includes a memory (136) for storing machine executable instructions (170), and a processor (130) for controlling the medical imaging system. Execution of the machine executable instructions causes the processor to: receive (304, 1000) a tagged arterial spin labeled (ASL) magnitude image (148) of a region of interest of a subject (118); receive (306, 1002) a control ASL magnitude image (150) of the region of interest of the subject; construct (308, 1004) an arterial image (152) by subtracting the control ASL magnitude image and the tagged ASL magnitude image; construct (310, 1006) an arterial mask (154) using the arterial image by identifying arteries in the arterial image; receive (312, 1008) a phase contrast magnetic resonance image (156, 158, 160) of at least a portion of the region of interest of the subject; and construct a venous image (164) at least partially by setting voxels of the phase contrast image within the at least a portion of the region of interest that are within the arterial mask to a predetermined background value.

公开(公告)号：US20150355305A1

公开(公告)日：2015-12-10

申请号：US14760845

申请日：2013-12-31

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Michael Gunter Helle ,  Tim Nielsen

IPC: G01R33/563 ,  G01R33/385 ,  G01R33/54

CPC classification number: G01R33/56366 ,  G01R33/3854 ,  G01R33/543

Abstract: A magnetic resonance imaging (MRI) system (100, 600) that generates information indicative of a fluid flow in accordance with a pseudo-continuous arterial spin labeling (pCASL) method. The MRI system may include at least one controller (104, 610) configured to generate a pseudo-continuous arterial spin labeling (pCASL) pulse sequence (200) including at least a first gradient (GR) pulse sequence (207) having a sinusoidal waveform including a plurality of cycles, and a second radio frequency (RF) pulse sequence (205) including a half-wave rectified sinusoidal waveform having a plurality of cycles and which is synchronous with the first GR pulse sequence; label at least part of the fluid flow in a labeling region during a labeling mode using the pCASL pulse sequence; acquire label and control image information of the fluid flow at an imaging region proximal to downstream of the labeling region; and/or generate image information in accordance with a difference of the acquired label and control image information. The sinusoidal gradient waveform results in less acoustic noise during execution of the pulse sequence.

Abstract translation: 根据伪连续动脉自旋标记（pCASL）方法产生指示流体流动的信息的磁共振成像（MRI）系统（100,600）。 MRI系统可以包括被配置为产生伪连续动脉自旋标记（pCASL）脉冲序列（200）的至少一个控制器（104,610），该脉冲序列（200）至少包括具有正弦波形的第一梯度（GR）脉冲序列（207） 包括多个周期，以及第二射频（RF）脉冲序列（205），其包括具有多个周期并与第一GR脉冲序列同步的半波整流正弦波形; 在使用pCASL脉冲序列的标记模式期间在标记区域中标记至少一部分流体流动; 获取标签和控制在标签区域下游的成像区域处的流体流动的图像信息; 和/或根据获取的标签和控制图像信息的差异生成图像信息。 正弦梯度波形在执行脉冲序列期间导致较少的声学噪声。