公开(公告)号：US20090266203A1

公开(公告)日：2009-10-29

申请号：US12111661

申请日：2008-04-29

申请人： Shawn G. Orr ,  Michael J. Oldham

发明人： Shawn G. Orr ,  Michael J. Oldham

IPC分类号： B25B13/48 ,  B25B27/00

CPC分类号： B25B27/00 ,  A62C35/68 ,  B25B9/00 ,  Y10T29/49826

摘要： An installation tool may include an extension member, a body portion disposed on the extension member, and a plurality of fingers flexibly protruding from the body portion. The plurality of fingers are adapted to releasably engage a cover assembly. The plurality of fingers and the body portion cooperate to retain the cover assembly in a first direction and allow disengagement of the cover assembly in a second direction.

摘要翻译： 安装工具可以包括延伸构件，设置在延伸构件上的主体部分和从主体部分柔性地突出的多个手指。 多个指状物适于可释放地接合盖组件。 多个指状物和主体部分协作以将盖组件保持在第一方向上，并且允许盖组件沿第二方向脱离。

公开(公告)号：US6066338A

公开(公告)日：2000-05-23

申请号：US94679

申请日：1998-06-15

申请人： Michael J. Oldham ,  Bruce F. Rose ,  Howard C. Krivan

发明人： Michael J. Oldham ,  Bruce F. Rose ,  Howard C. Krivan

IPC分类号： A61F6/08 ,  A61K38/16 ,  A61K38/17 ,  A61K91/14 ,  A01N37/18

CPC分类号： A61K38/17 ,  A61F6/08 ,  A61K38/168 ,  A61K38/1709 ,  Y10S424/14 ,  Y10S514/841 ,  Y10S514/843 ,  Y10S514/953 ,  Y10S514/967

摘要： In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections.The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.

摘要翻译： 为了防止性传播疾病（STD's）的受孕和/或扩散，可以在性交前向阴道施用一种或多种能够结合精子和/或负责STD的病原微生物的凝集素。 凝集素固定精子使其不能受精，并且还结合微生物使其成为非致病性或细胞以防止微生物感染。 也可以施用凝露素治疗性传播的阴道感染。 本发明还包括用于放置在阴道的拱顶中的装置，其包括围绕子宫颈的环和横跨环的中心孔的膜，以防止射精与子宫颈组织的直接接触。 该装置浸渍或涂有凝集素，并在一段时间内将其释放到阴道环境中。

公开(公告)号：US08052187B2

公开(公告)日：2011-11-08

申请号：US13009334

申请日：2011-01-19

申请人： Shawn G. Orr ,  Michael J. Oldham

发明人： Shawn G. Orr ,  Michael J. Oldham

IPC分类号： B25J1/00

CPC分类号： B25B27/00 ,  A62C35/68 ,  B25B9/00 ,  Y10T29/49826

摘要： An installation tool may include an extension member, a body portion disposed on the extension member, and a plurality of fingers flexibly protruding from the body portion. The plurality of fingers are adapted to releasably engage a cover assembly. The plurality of fingers and the body portion cooperate to retain the cover assembly in a first direction and allow disengagement of the cover assembly in a second direction.

公开(公告)号：US06743773B2

公开(公告)日：2004-06-01

申请号：US10259610

申请日：2002-09-30

申请人： Michael J. Oldham ,  Bruce F. Rose

发明人： Michael J. Oldham ,  Bruce F. Rose

IPC分类号： A01N3718

CPC分类号： A61K38/17 ,  A61F6/08 ,  A61K38/168 ,  A61K38/1709 ,  Y10S424/14 ,  Y10S514/841 ,  Y10S514/843 ,  Y10S514/931 ,  Y10S514/932 ,  Y10S514/933 ,  Y10S514/934 ,  Y10S514/953 ,  Y10S514/967 ,  Y10T428/31971

摘要： In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.

摘要翻译： 为了防止性传播疾病（STD's）的受孕和/或扩散，可以在性交前向阴道施用一种或多种能够结合精子和/或负责STD的病原微生物的凝集素。 凝集素固定精子使其不能施肥，并且还结合微生物使其成为非致病性或细胞以防止微生物感染。 也可以施用凝露素治疗性传播的阴道感染。 本发明还包括用于放置在阴道的拱顶中的装置，其包括围绕子宫颈的环和横跨环的中心孔的膜，以防止射精与子宫颈组织的直接接触。 该装置浸渍或涂有凝集素，并在一段时间内将其释放到阴道环境中。

公开(公告)号：US6074671A

公开(公告)日：2000-06-13

申请号：US97669

申请日：1998-06-16

申请人： Michael J. Oldham ,  Bruce F. Rose ,  Howard C. Krivan

发明人： Michael J. Oldham ,  Bruce F. Rose ,  Howard C. Krivan

IPC分类号： A61F6/08 ,  A61K38/16 ,  A61K38/17 ,  A61F5/44 ,  A61L15/00 ,  A61M31/00

CPC分类号： A61F6/08 ,  A61K38/168 ,  A61K38/1709

摘要： In order to prevent conception and/or infection by sexually transmitted diseases (STDs) one or more lectins capable of binding sperm or agglutinable components of male ejaculate and/or the pathogenic microorganisms responsible for STDs or the carbohydrate moieties expressed on cell surfaces by which the microorganisms bind to the cells, are administered to the vagina prior to sexual intercourse. The lectins prevent conception by binding to the sperm or agglutinable components of male ejaculate to render the sperm incapable of fertilization. They also bind to the pathogenic microorganisms to render them non-pathogenic or to carbohydrates expressed on cell surfaces to prevent infection by the microorganisms or treat such infections. Lectins can also be administered to treat sexually transmitted vaginal infections. The lectins can also be applied to or contained within a condom. The condom may carry the lectins either within the hollow interior of the condom or impregnated into, linked to, or coated upon its membrane body. Lectins may also be incorporated in the same way into a surgical glove for protection against infection by pathogenic microorganisms.

摘要翻译： 为了防止性传播疾病（STD）的受孕和/或感染，一种或多种凝集素能够结合雄性射精精子或可凝结组分和/或负责STD的病原微生物或细胞表面上表达的碳水化合物部分， 微生物结合细胞，在性交前施用于阴道。 凝集素通过与男性射精的精子或可凝结成分结合来预防受孕，使精子无能力受精。 它们还结合致病微生物使其非致病性或在细胞表面上表达的碳水化合物以防止微生物感染或治疗这些感染。 也可以施用凝露素治疗性传播的阴道感染。 凝集素也可以应用于或包含在避孕套内。 避孕套可以在避孕套的中空内部携带凝集素，或浸入，连接到或涂覆在其膜体上。 胶质素也可以以相同的方式并入手术手套中，以防止致病微生物感染。

公开(公告)号：US5840771A

公开(公告)日：1998-11-24

申请号：US938831

申请日：1997-09-26

申请人： Michael J. Oldham ,  Bruce F. Rose

发明人： Michael J. Oldham ,  Bruce F. Rose

IPC分类号： A61F6/08 ,  A61K38/16 ,  A61K38/17 ,  A01N65/00 ,  A61K35/78 ,  A61K39/385

CPC分类号： A61K38/17 ,  A61F6/08 ,  A61K38/168 ,  A61K38/1709 ,  Y10S424/14 ,  Y10S514/841 ,  Y10S514/843 ,  Y10S514/931 ,  Y10S514/932 ,  Y10S514/933 ,  Y10S514/934 ,  Y10S514/953 ,  Y10S514/967 ,  Y10T428/31971

摘要： In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.

摘要翻译： 为了防止性传播疾病（STD's）的受孕和/或扩散，可以在性交前向阴道施用一种或多种能够结合精子和/或负责STD的病原微生物的凝集素。 凝集素固定精子使其不能施肥，并且还结合微生物使其成为非致病性或细胞以防止微生物感染。 也可以施用凝露素治疗性传播的阴道感染。 本发明还包括用于放置在阴道的拱顶中的装置，其包括围绕子宫颈的环和横跨环的中心孔的膜，以防止射精与子宫颈组织的直接接触。 该装置浸渍或涂有凝集素，并在一段时间内将其释放到阴道环境中。