Method for producing recombinant proteins
    11.
    发明申请
    Method for producing recombinant proteins 审中-公开
    生产重组蛋白的方法

    公开(公告)号:US20080076155A1

    公开(公告)日:2008-03-27

    申请号:US11984021

    申请日:2007-11-13

    申请人: Victor Fung

    发明人: Victor Fung

    IPC分类号: C12P21/04

    摘要: A method for producing recombinant proteins, preferably fusion proteins comprising an Fc portion of an immunoglobulin molecule, more preferably fusion proteins comprising an extracellular domain of a tumor necrosis factor receptor fused to the Fc portion of an immunoglobulin molecule, is disclosed. The method of the present invention allows a reduction of misfolding of the protein, thereby giving rise to a higher yield of the desired protein.

    摘要翻译: 公开了一种生产重组蛋白的方法,优选包含免疫球蛋白分子的Fc部分的融合蛋白,更优选包含与免疫球蛋白分子的Fc部分融合的肿瘤坏死因子受体的细胞外结构域的融合蛋白。 本发明的方法允许减少蛋白质的错误折叠,从而产生更高的所需蛋白质的产率。

    Microcell layout having directional and omnidirectional antennas
defining a rectilinear layout in a building
    12.
    发明授权
    Microcell layout having directional and omnidirectional antennas defining a rectilinear layout in a building 失效
    具有在建筑物中定义直线布局的定向和全向天线的微小区布局

    公开(公告)号:US5564121A

    公开(公告)日:1996-10-08

    申请号:US292275

    申请日:1994-08-18

    摘要: A radio communication system is provided wherein radio coverage building blocks are used to provide uniform radio coverage to rectilinear floor layouts of buildings. The building blocks are comprised of directional and omnidirectional antennas which are applied to rectangular and irregular layouts. Each building block is divided into multiple small zones and each zone is covered by an antenna. Each antenna in the building block is connected to the same base station through a low loss coupling matrix and all antennas transmit and receive simultaneously. The directional antennas are located near the boundary of the service area. An omnidirectional or directional antenna at the center of the zone may be used to fill the rest of the area.

    摘要翻译: 提供了一种无线电通信系统,其中无线电覆盖构建块用于向建筑物的直线地板布局提供统一的无线电覆盖。 构造块由方向和全向天线组成,应用于矩形和不规则布局。 每个建筑块分为多个小区域,每个区域都被天线覆盖。 构建块中的每个天线通过低损耗耦合矩阵连接到同一基站,并且所有天线同时发射和接收。 定向天线位于服务区域边界附近。 区域中心的全向或定向天线可用于填充该区域的其余部分。

    Computer-based bit error simulation for digital wireless communications
    13.
    发明授权
    Computer-based bit error simulation for digital wireless communications 失效
    用于数字无线通信的基于计算机的比特误差模拟

    公开(公告)号:US5233628A

    公开(公告)日:1993-08-03

    申请号:US706806

    申请日:1991-05-29

    IPC分类号: H04B17/00

    CPC分类号: H04B17/3912 H04B17/373

    摘要: A communications stimulation system allows a user to perform a quantitative or subjective test of digital baseband devices over wireless channels using actual measured or modeled propagation data. The digital wireless communication simulation system is capable of simulating the transient nature of channels and radio hardware so that loss of synchronization can be included in the simulation. The simulator is a combination of computer software and hardware that computes a convolution, in the time domain, of a sequence of binary digits or data symbols (i.e., the data stream) with a computer model of a radio transmitter, a propagation channel or channels and a receiver. The transmitter typically comprises a coder, a pulse shaper, a modulator, and a spreader. The propagation channel or channels may include impulsive and average noise levels, co-channel interference and adjacent interference levels, fading and multipath propagation events, and non-linear channel and radio system effects. The receiver system typically comprises at least a filter bank, a demodulator, a despreader, a synchronizer, a detector, and a decoder. The data stream may either be random or applied by the user. The software computes the bit-by-bit sequence for replay at a later time. Once stored, the bit-by-bit error sequence can be clocked through a hardware data port and compared with an applied data stream in real time. The output of the hardware data port is a real time sequence of bits that has errors due to the bit-by-bit simulation computed earlier by the software.

    摘要翻译: 通信刺激系统允许用户使用实际测量或建模的传播数据通过无线信道对数字基带设备进行定量或主观测试。 数字无线通信仿真系统能够模拟信道和无线电硬件的瞬态特性,从而可以在仿真中包含同步丢失。 模拟器是计算机软件和硬件的组合,其在时域中使用无线电发射机的计算机模型,传播信道或信道计算二进制数字或数据符号(即,数据流)序列的卷积 和接收器。 发射机通常包括编码器,脉冲整形器,调制器和扩展器。 传播信道或信道可以包括脉冲和平均噪声电平,同信道干扰和相邻干扰电平,衰落和多径传播事件以及非线性信道和无线电系统效应。 接收机系统通常至少包括滤波器组,解调器,解扩器,同步器,检测器和解码器。 数据流可以是用户随机的或应用的。 该软件将在稍后的时间内逐行计算重播。 一旦存储,逐位错误序列可以通过硬件数据端口进行计时,并与应用的数据流进行实时比较。 硬件数据端口的输出是由于软件较早计算的逐位仿真而具有错误的实时比特序列。