公开(公告)号：US5141553A

公开(公告)日：1992-08-25

申请号：US458087

申请日：1983-01-14

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Klaus Lurssen

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Klaus Lurssen

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are ether derivatives of substituted 1-hydroxyalkyl-azoles, of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R.sup.1 represents a substituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl radical or, if either A represents a nitrogen atom, or if A represents the CH group and at the same B represents oxygen or sulphur, R.sup.1 also represents an unsubstituted alkyl radical,R.sup.2 represents an alkyl, alkenyl, alkinyl, optionally substituted phenyl or optionally substituted benzyl radical,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy radical andm is 0, 1, 2 or 3,and acid addition salts and metal salt complexes thereof, are novel, are prepared as described, and fine use as fungicides and as agents for regulating plant growth.

公开(公告)号：US4960456A

公开(公告)日：1990-10-02

申请号：US354329

申请日：1989-05-19

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D303/22 ,  C07D303/34 ,  C07D405/06 ,  C07D521/00

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are substituted 1-hydroxyalkyl-azolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents a substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cyclo-alkyl or optionally substituted phenyl group,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.

公开(公告)号：US4935049A

公开(公告)日：1990-06-19

申请号：US255207

申请日：1988-10-07

申请人： Wolfgang Kramer ,  Erik Regel ,  Karl H. Buchel ,  Stefan Dutzmann ,  Wilhelm Brandes ,  Klaus Lurssen

发明人： Wolfgang Kramer ,  Erik Regel ,  Karl H. Buchel ,  Stefan Dutzmann ,  Wilhelm Brandes ,  Klaus Lurssen

IPC分类号： A01N43/78 ,  A01N43/84 ,  C07D277/24 ,  C07D277/28 ,  C07D277/42 ,  C07D417/06 ,  C07D417/14 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/78 ,  C07D233/56 ,  C07D249/08 ,  C07D277/24 ,  C07D277/28

摘要： New substituted azolylmethylcarbinols of the formula ##STR1## in which Ar stands for optionally substituted aryl,Z stands for nitrogen or an CH group andR stands for alkyl, dialkylaminoalkyl, alkenyl, alkinyl, alkoxyalkyl, optionally substituted aralkyl, optionally substituted aryloxyalkyl, optionally substituted aryl or a radical of the formula ##STR2## whereinR.sup.1 stands for hydrogen, alkyl, alkenyl, alkinyl or cycloalkyl andR.sup.2 stands for hydrogen, alkyl, alkoxyalkyl, alkenyl, alkinyl, cycloalkyl, cycloalkylalkyl, for optionally substituted aryl or for optionally substituted aralkyl, orR.sup.1 and R.sup.2 together with the nitrogen atom to which they are bonded stand for an optionally substituted heterocyclic ring which cna optionally contain further heteroatoms,and acid addition salts and metal salt complexes thereof, and the use of the novel compounds as fungicides and plant growth regulators.

摘要翻译： 式（I）的新取代的吡唑甲基甲醇其中Ar代表任选取代的芳基，Z代表氮或CH基团，R代表烷基，二烷基氨基烷基，烯基，炔基，烷氧基烷基，任选取代的芳烷基，任选取代的芳氧基烷基 ，任选取代的芳基或下式的基团其中R1代表氢，烷基，烯基，炔基或环烷基，R2代表氢，烷基，烷氧基烷基，烯基，炔基，环烷基，环烷基烷基，任选取代的芳基或 任选取代的芳烷基，或R 1和R 2与它们所键合的氮原子一起代表任选取代的杂环，其任选地含有其它杂原子，以及其酸加成盐和金属盐络合物，以及将新化合物用作 杀真菌剂和植物生长调节剂。

公开(公告)号：US4734126A

公开(公告)日：1988-03-29

申请号：US683891

申请日：1984-12-20

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D303/22 ,  C07D303/34 ,  C07D405/06 ,  C07D521/00 ,  A61K31/41

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are substituted 1-hydroxyalkyl-azolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl group,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.

摘要翻译： 化合物，其中A表示氮原子或CH基团，B表示氧，硫或CH2基团，其中R表示取代的烷基，且表示取代的烷基， B代表硫的情况也代表未取代的烷基，任选取代的环烷基或任选取代的苯基，Z代表卤素原子或烷基，环烷基，烷氧基，烷硫基，卤代烷基，卤代烷氧基，卤代烷硫基，任选取代的苯基， 苯氧基，任选取代的苯基烷基或任选取代的苯基烷氧基，m为0,1,2或3，其酸加成盐和金属盐络合物是新的，如上所述制备，可用作杀真菌剂和植物生长调节剂。

公开(公告)号：US4729783A

公开(公告)日：1988-03-08

申请号：US715574

申请日：1985-03-22

申请人： Erik Regel ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes

发明人： Erik Regel ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes

IPC分类号： A01N43/653 ,  C07C45/63 ,  C07C49/16 ,  C07D249/08 ,  C07D521/00 ,  A61K31/41

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07C45/63 ,  C07C49/16 ,  C07D233/56 ,  C07D249/08

摘要： Halogenated triazolylvinyl keto derivatives and carbinol derivatives of the general formula ##STR1## in which A represents a keto group or a CH(OH) grouping,X represents a hydrogen or halogen atom,Y represents a halogen atom,R represents a halogen atom, an alkyl, halogenoalkyl, halogenoalkoxy, alkoxy, alkylthio, halogenoalkylthio, alkylamino, dialkylamino, nitro, cyano, hydroxyl or alkylcarbonyloxy radical, an optionally substituted phenyl radical, an optionally substituted phenoxy radical or an optionally substituted benzyloxy radical andn is 0, 1, 2 or 3,and physiologically acceptable acid addition salts and metal salt complexes thereof are outstandingly effective as plant growth regulators and as fungicides. The inventive compounds can be prepared by reacting a triazolylketone with an aldehyde.

摘要翻译： 卤代三唑基乙烯基酮衍生物和通式为其中A表示酮基或CH（OH）基的通式为（I）的甲醇衍生物，X表示氢或卤素原子，Y表示卤素原子，R表示卤素 烷氧基，烷硫基，卤代烷硫基，烷基氨基，二烷基氨基，硝基，氰基，羟基或烷基羰基氧基，任意取代的苯基，任意取代的苯氧基或任意取代的苄氧基，n为0， 1,2或3，其生理上可接受的酸加成盐和金属盐络合物作为植物生长调节剂和杀真菌剂是非常有效的。 本发明化合物可以通过使三唑基酮与醛反应来制备。

公开(公告)号：US4728356A

公开(公告)日：1988-03-01

申请号：US754788

申请日：1985-07-12

申请人： Hans-Ludwig Elbe ,  Wolf Reiser ,  Erik Regel ,  Karl H. Buchel ,  Paul Reinecke ,  Wilhelm Brandes ,  Klaus Lurssen ,  Paul-Ernst Frohberger

发明人： Hans-Ludwig Elbe ,  Wolf Reiser ,  Erik Regel ,  Karl H. Buchel ,  Paul Reinecke ,  Wilhelm Brandes ,  Klaus Lurssen ,  Paul-Ernst Frohberger

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： A substituted azolylvinyl ketone or carbinol of the formula ##STR1## in which R.sup.1 represents optionally substituted cycloalkyl with 3 to 5 carbon atoms, substituted cyclohexyl or the grouping ##STR2## wherein R.sup.3 represents optionally substituted phenyl, alkenyl, alkinyl, cyano or the grouping --Z--R.sup.4,whereinR.sup.4 represents alkyl, halogenoalkyl, optionally substituted phenyl or optionally substituted phenylalkyl andZ represents O, S, SO or SO.sub.2,n represents a number from 0 to 2,R.sup.2 represents alkyl, alkenyl, alkinyl, in each case optionally substituted phenyl or phenylalkyl, or in each case optionally substituted cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, bicycloalkyl or bicycloalkenyl, but R.sup.2 does not represent optionally substituted phenyl at the same time as R.sup.1 represents optionally substituted cycloalkyl with 3 to 5 carbon atoms or substituted cyclohexyl or R.sup.3 represents optionally substituted phenyl,X represents the CO or CH(OH) group andY represents a nitrogen atom or the CH group,or an addition product thereof with an acid or metal salt.The products are active in combating fungi and in regulating the growth of plants.

摘要翻译： 其中R 1表示任选取代的具有3至5个碳原子的环烷基，取代的环己基或基团，其中R 3表示任选取代的苯基，烯基，炔基，氰基或基团 - Z-R4，其中R4代表烷基，卤代烷基，任选取代的苯基或任选取代的苯基烷基，Z代表O，S，SO或SO 2，n代表0至2的数，R 2代表烷基，烯基，炔基， 取代的苯基或苯基烷基，或者在每种情况下都是任选取代的环烷基，环烷基烷基，环烯基，环烯基烷基，双环烷基或双环烯基，但R 2不同时代表任选取代的苯基，其中R 1表示任选取代的具有3至5个碳原子的环烷基或取代的环己基 或R 3表示任选取代的苯基，X表示CO或CH（OH）基团，Y表示氮气 m或CH基团，或其与酸或金属盐的加成产物。 该产品在防治真菌和调节植物生长方面发挥积极作用。

公开(公告)号：US4530715A

公开(公告)日：1985-07-23

申请号：US438448

申请日：1982-11-02

申请人： Eckart Kranz ,  Karl H. Buchel ,  Udo Kraatz ,  Erik Regel ,  Wilhelm Brandes ,  Paul-Ernst Frohberger ,  Klaus Lurssen

发明人： Eckart Kranz ,  Karl H. Buchel ,  Udo Kraatz ,  Erik Regel ,  Wilhelm Brandes ,  Paul-Ernst Frohberger ,  Klaus Lurssen

IPC分类号： A01N43/653 ,  C07C45/63 ,  C07D249/08 ,  C07D521/00 ,  A01N43/64 ,  A01N55/02 ,  C07F3/00

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07C45/63 ,  C07D233/56 ,  C07D249/08

摘要： Cycloalkyl (.alpha.-triazolyl-.beta.-hydroxy)-ketones of the general formula ##STR1## in which R.sup.1 represents an optionally substituted cycloalkyl group, andR.sup.2 represents a halogenoalkyl, halogenoalkenyl or alkoxycarbonyl group,and their physiologically acceptable acid addition salts and metal salt complexes are new, are prepared as described and find use as fungicides and plant growth regulators.

摘要翻译： 其中R 1表示任选取代的环烷基，R 2表示卤代烷基，卤代烯基或烷氧基羰基，以及它们的生理上可接受的酸加成盐（Ⅰ）所示的环烷基（α-三唑基-β-羟基） - 酮 和金属盐络合物是新的，按照描述制备并用作杀真菌剂和植物生长调节剂。

公开(公告)号：US4699645A

公开(公告)日：1987-10-13

申请号：US772829

申请日：1985-09-05

申请人： Erik Regel ,  Wilfried Draber ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Klaus Lurssen

发明人： Erik Regel ,  Wilfried Draber ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Klaus Lurssen

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Compound which are azolyl-thioether derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents a CO or CH(OH) group,m is 0 or 2,R.sup.1 represents an optionally substituted phenyl radical andR.sup.2 represents an optionally substituted cycloalkyl radical or a grouping of the general formula ##STR2## wherein X and Y are identical or different and represent a hydrogen or halogen atom,Z represent an alkyl, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylthio, optionally substituted benzyloxy, optionally substituted benzylthio, alkoxy, alkylthio, halogenoalkoxy, halogenoalkylthio, alkoxycar-onyl or cyano radical, andn is 0 or 1,and the acid addition salts and metal salt complexes thereof, are novel and prepared by several processes described and find use as fungicides and as agents for regulating plant growth.

摘要翻译： 化合物，其中A表示氮原子或CH基团，B表示CO或CH（OH）基团，m为0或2，通式为（I）的吡唑基 - 硫醚衍生物，R 1表示任选地 取代的苯基，并且R 2表示任选取代的环烷基或通式为其中X和Y相同或不同并且表示氢或卤素原子的基团，Z表示烷基，任选取代的苯基，任选取代的苯氧基， 任选取代的苯硫基，任选取代的苄氧基，任选取代的苄硫基，烷氧基，烷硫基，卤代烷氧基，卤代烷硫基，烷氧基羰基或氰基，n为0或1，其酸加成盐和金属盐络合物是新颖的， 描述的几种方法用作杀真菌剂和用作调节植物生长的试剂。

公开(公告)号：US4559077A

公开(公告)日：1985-12-17

申请号：US454303

申请日：1982-12-29

申请人： Erik Regel ,  Wilfried Draber ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Klaus Lurssen

发明人： Erik Regel ,  Wilfried Draber ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Klaus Lurssen

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00 ,  A01N43/64

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are azolyl-thioether derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents a CO or CH(OH) group,m is 0 or 2,R.sup.1 represents an optionally substituted phenyl radical andR.sup.2 represents an optionally substituted cycloalkyl radical or a grouping of the general formula ##STR2## wherein X and Y are identical or different and represent a hydrogen or halogen atom,Z represents an alkyl, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylthio, optionally substituted benzyloxy, optionally substituted benzylthio, alkoxy, alkylthio, halogenoalkoxy, halogenoalkylthio, alkoxycar-onyl or cyano radical, andn is 0 or 1,and the acid addition salts and metal salt complexes thereof, are novel and prepared by several processes described and find use as fungicides and as agents for regulating plant growth.

摘要翻译： 作为通式为（A）的唑基 - 硫醚衍生物的化合物，其中A表示氮原子或CH基团，B表示CO或CH（OH）基团，m表示0或2，R1表示任选的 取代的苯基，R 2表示任选取代的环烷基或通式为其中X和Y相同或不同并且表示氢或卤素原子的基团，Z表示烷基，任选取代的苯基，任选取代的苯氧基， 任选取代的苯硫基，任选取代的苄氧基，任选取代的苄硫基，烷氧基，烷硫基，卤代烷氧基，卤代烷硫基，烷氧基羰基或氰基，n为0或1，其酸加成盐和金属盐络合物是新颖的， 描述的几种方法用作杀真菌剂和用作调节植物生长的试剂。

公开(公告)号：US4507141A

公开(公告)日：1985-03-26

申请号：US354122

申请日：1982-03-02

申请人： Erik Regel ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger

发明人： Erik Regel ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger

IPC分类号： A01N43/653 ,  C07D249/08 ,  C07D521/00 ,  A01N43/64

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Triazolylalkyl-thioether plant growth regulators and fungicides of the formula ##STR1## in which A represents the keto group or the CH(OH) group,R.sup.1 represents alkyl, alkenyl, alkynyl, optionally substituted cycloalkyl, alkylaminoalkyl, alkoxycarbonylalkyl, optionally substituted phenyl or optionally substituted phenylalkyl,R.sup.2 represents alkyl,R.sup.3 represents alkyl or halogenoalkyl,R.sup.4 represents alkyl, halogenoalkyl, alkoxy, alkoxymethyl, alkylthio, alkylthiomethyl, optionally substituted phenyl, optionally substituted benzyl, optionally substituted phenoxy, optionally substituted phenoxymethyl, optionally substituted phenylthio, optionally substituted phenylthiomethyl, alkenyl, alkoxycarbonyl or cyano, orR.sup.3 and R.sup.4, conjointly with the carbon atom to which they are bonded, represent optionally substituted cycloalkyl andX.sup.1, X.sup.2, X.sup.3, X.sup.4 and X.sup.5 are selected independently and each represent hydrogen, hologen, alkyl, halogenoalkyl, halogenoalkoxy, alkoxy, alkylthio, halogenoalkylthio, alkylamino, dialkylamino, nitro, cyano, hydroxyl, alkoxycarbonyl, optionally substituted phenyl, optionally substituted phenoxy or optionally substituted benzyloxy,or an acid addition salt or metal salt complex thereof.

摘要翻译： 三唑基烷基 - 硫醚植物生长调节剂和式“IMAGE”的杀真菌剂，其中A代表酮基或CH（OH）基团，R1代表烷基，烯基，炔基，任选取代的环烷基，烷基氨基烷基，烷氧基羰基烷基，任选取代的苯基或任选地 取代的苯基烷基，R 2表示烷基，R 3表示烷基或卤代烷基，R 4表示烷基，卤代烷基，烷氧基，烷氧基甲基，烷硫基，烷硫基甲基，任选取代的苯基，任选取代的苄基，任选取代的苯氧基，任选取代的苯氧基甲基，任选取代的苯硫基，任选取代的苯硫基甲基 ，烯基，烷氧基羰基或氰基，或者R 3和R 4与它们所键合的碳原子结合，表示任选取代的环烷基，且X 1，X 2，X 3，X 4和X 5独立选择，各自表示氢，氢原子，烷基，卤代烷基 ，卤代烷氧基，烷氧基，烷硫基，卤代烷硫基，烷基 硝基，氰基，羟基，烷氧基羰基，任选取代的苯基，任意取代的苯氧基或任意取代的苄氧基，或其酸加成盐或金属盐络合物。