公开(公告)号：US20190388439A1

公开(公告)日：2019-12-26

申请号：US16554539

申请日：2019-08-28

Applicant: LEO Pharma A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/593 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61M11/00 ,  A61K9/00 ,  A61K9/12 ,  A61K31/573 ,  A61K31/58 ,  A61M35/00 ,  A61K47/14 ,  A61K47/22

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

公开(公告)号：US20190015430A1

公开(公告)日：2019-01-17

申请号：US16135366

申请日：2018-09-19

Applicant: LEO Pharma A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Ridahi SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/593 ,  A61K47/08 ,  A61K9/12 ,  A61M35/00 ,  A61M11/00 ,  A61K47/22 ,  A61K47/14 ,  A61K9/00 ,  A61K47/06 ,  A61K31/59 ,  A61K31/58 ,  A61K31/573 ,  B65D83/20 ,  B65D83/14

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

公开(公告)号：US20160324875A1

公开(公告)日：2016-11-10

申请号：US15214216

申请日：2016-07-19

Applicant: LEO PHARMA A/S

Inventor： Karsten PETERSSON

IPC: A61K31/592 ,  A61K47/18 ,  A61K47/06 ,  A61K9/00 ,  A61K47/44 ,  A61K47/14

CPC classification number: A61K31/592 ,  A61K9/0014 ,  A61K9/1075 ,  A61K31/593 ,  A61K47/06 ,  A61K47/14 ,  A61K47/18 ,  A61K47/44

Abstract: A pharmaceutical composition comprising a vitamin D derivative or analogue as the active ingredient dissolved in a three-component surfactant-solvent mixture is useful in the treatment of dermal disorders or conditions.

Abstract translation: 包含溶解在三组分表面活性剂 - 溶剂混合物中的作为活性成分的维生素D衍生物或类似物的药物组合物可用于治疗真皮病症或病症。

公开(公告)号：US20160206629A1

公开(公告)日：2016-07-21

申请号：US15084210

申请日：2016-03-29

Applicant: LEO Pharma A/S

Inventor： Karsten PETERSSON ,  Kit FREDERIKSEN ,  Diana OMKVIST ,  Jörgen JANSSON

IPC: A61K31/573 ,  A61K47/14 ,  A61K9/70 ,  A61K47/26 ,  A61K9/00 ,  A61K47/32 ,  A61K47/10

CPC classification number: A61K31/573 ,  A61K9/0014 ,  A61K9/124 ,  A61K9/7015 ,  A61K47/06 ,  A61K47/08 ,  A61K47/10 ,  A61K47/14 ,  A61K47/22 ,  A61K47/26 ,  A61K47/32 ,  A61K47/38 ,  A61K47/44 ,  B65D83/752

Abstract: A film-forming pharmaceutical composition for dermal application comprises at least one therapeutically active ingredient dissolved in a volatile solvent, the composition further comprising a film-forming polymer, a plasticizer and an oily release-enhancing agent. The composition is capable of forming, after application on skin and evaporation of the solvent, a continuous phase comprising the film-forming polymer and the plasticizer and a dispersed phase comprising droplets of the oily release-enhancing agent.