公开(公告)号：US20150335575A1

公开(公告)日：2015-11-26

申请号：US14707662

申请日：2015-05-08

Applicant: LEO PHARMA A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K9/12 ,  A61K31/59 ,  A61M11/00 ,  A61K47/06 ,  A61K47/08 ,  A61K31/573 ,  A61K9/00

CPC classification number: A61K31/593 ,  A61K9/0014 ,  A61K9/122 ,  A61K9/124 ,  A61K31/573 ,  A61K31/58 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61K47/14 ,  A61K47/22 ,  A61M11/00 ,  A61M35/003 ,  A61M2210/04 ,  B65D83/207 ,  B65D83/752 ,  A61K2300/00

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

公开(公告)号：US20150313919A1

公开(公告)日：2015-11-05

申请号：US14707733

申请日：2015-05-08

Applicant: LEO PHARMA A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/59 ,  A61K31/573

CPC classification number: A61K31/593 ,  A61K9/0014 ,  A61K9/122 ,  A61K9/124 ,  A61K31/573 ,  A61K31/58 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61K47/14 ,  A61K47/22 ,  A61M11/00 ,  A61M35/003 ,  A61M2210/04 ,  B65D83/207 ,  B65D83/752 ,  A61K2300/00

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

Abstract translation: 本发明涉及包含生物活性维生素D衍生物或类似物和皮质类固醇的局部喷雾组合物，及其用于治疗真皮疾病和病症。

公开(公告)号：US20230404909A1

公开(公告)日：2023-12-21

申请号：US18154566

申请日：2023-01-13

Applicant: LEO Pharma A/S

Inventor： Karsten PETERSSON ,  Karen Margrethe ENGELL ,  Jorgen JANSSON ,  Kim Troensegaard NIELSEN ,  Andre Huss ERIKSSON ,  Anne MOORE ,  Sonja VUCEN ,  Caroline O'SULLIVAN ,  Abina CREAN

IPC: A61K9/00 ,  A61K31/573 ,  A61K31/593 ,  A61K31/59 ,  A61K47/32 ,  A61K47/34 ,  A61M37/00

CPC classification number: A61K9/0021 ,  A61K31/573 ,  A61K31/593 ,  A61K31/59 ,  A61K47/32 ,  A61K47/34 ,  A61M37/0015 ,  A61M2037/0053 ,  A61M2037/0046 ,  A61M2037/0023 ,  A61M2037/0061

Abstract: The present invention relates to a microneedle patch composition comprising one or more microneedles each comprising: (a) a tapered tip portion containing a therapeutically active ingredient dispersed in a matrix of a biodegradable polymer capable of providing sustained release of the therapeutically active ingredient over a period of at least two days after insertion of the microneedle or microneedles into the skin, and (b) a fast dissolving microneedle backing layer portion containing a water-soluble polymer overlayering the tip portion, said microneedle or microneedles being attached to and extending from an adhesive surface of a removable substrate.

公开(公告)号：US20200009160A1

公开(公告)日：2020-01-09

申请号：US16554603

申请日：2019-08-28

Applicant: LEO Pharma A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/593 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61M11/00 ,  A61K9/00 ,  A61K9/12 ,  A61K31/573 ,  A61K31/58 ,  A61M35/00 ,  A61K47/14 ,  A61K47/22

Abstract: A Pharmaceutical Spray Composition Comprising a Vitamin D Analogue and a CorticosteroidThe present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

公开(公告)号：US20230398131A1

公开(公告)日：2023-12-14

申请号：US18154695

申请日：2023-01-13

Applicant: LEO Pharma A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/593 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61M11/00 ,  A61K9/00 ,  A61K9/12 ,  A61K31/573 ,  A61K31/58 ,  A61M35/00 ,  A61K47/14 ,  A61K47/22

CPC classification number: A61K31/593 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61M11/00 ,  A61K9/0014 ,  A61K9/122 ,  A61K31/573 ,  A61K31/58 ,  A61K9/124 ,  A61M35/003 ,  A61K47/14 ,  A61K47/22 ,  A61M2210/04 ,  B65D83/207

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

公开(公告)号：US20190381074A1

公开(公告)日：2019-12-19

申请号：US16554586

申请日：2019-08-28

Applicant: LEO Pharma A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/593 ,  A61K47/22 ,  A61K47/14 ,  A61M35/00 ,  A61K9/12 ,  A61K31/58 ,  A61K31/573 ,  A61K9/00 ,  A61M11/00 ,  A61K47/08 ,  A61K47/06 ,  A61K31/59

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

公开(公告)号：US20190381073A1

公开(公告)日：2019-12-19

申请号：US16554501

申请日：2019-08-28

Applicant: LEO Pharma A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/593 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61M11/00 ,  A61K9/00 ,  A61K9/12 ,  A61K31/573 ,  A61K31/58 ,  A61M35/00 ,  A61K47/14 ,  A61K47/22

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

公开(公告)号：US20210128588A1

公开(公告)日：2021-05-06

申请号：US16903730

申请日：2020-06-17

Applicant: LEO Pharma A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/593 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61M11/00 ,  A61K9/00 ,  A61K9/12 ,  A61K31/573 ,  A61K31/58 ,  A61M35/00 ,  A61K47/14 ,  A61K47/22

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

公开(公告)号：US20170065618A1

公开(公告)日：2017-03-09

申请号：US15297984

申请日：2016-10-19

Applicant: LEO PHARMA A/S

Inventor： Marianne LIND ,  Gritt RASMUSSEN ,  Mette Rydahl SONNE ,  Jens HANSEN ,  Karsten PETERSSON

IPC: A61K31/593 ,  A61K9/12 ,  A61K9/00 ,  A61M35/00 ,  A61K47/08 ,  A61K47/22 ,  A61K47/14 ,  A61M11/00 ,  A61K31/573 ,  A61K47/06

CPC classification number: A61K31/593 ,  A61K9/0014 ,  A61K9/122 ,  A61K9/124 ,  A61K31/573 ,  A61K31/58 ,  A61K31/59 ,  A61K47/06 ,  A61K47/08 ,  A61K47/14 ,  A61K47/22 ,  A61M11/00 ,  A61M35/003 ,  A61M2210/04 ,  B65D83/207 ,  B65D83/752 ,  A61K2300/00

Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.

Abstract translation: 本发明涉及包含生物活性维生素D衍生物或类似物和皮质类固醇的局部喷雾组合物，及其用于治疗真皮疾病和病症。

公开(公告)号：US20140322331A1

公开(公告)日：2014-10-30

申请号：US14220843

申请日：2014-03-20

Applicant: LEO PHARMA A/S

Inventor： Karsten PETERSSON

IPC: A61K31/592 ,  A61K45/06 ,  A61K9/06 ,  C07C35/21

CPC classification number: A61K31/592 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/146 ,  A61K31/593 ,  A61K45/06 ,  C07C35/21 ,  Y10T428/2982

Abstract: Calcipotriol monohydrate nanocrystals prepared by the process disclosed herein may be incorporated in a pharmaceutical composition for use in the prevention or treatment of dermal diseases and conditions.

Abstract translation: 通过本文公开的方法制备的卡泊三醇一水合物纳米晶体可以掺入用于预防或治疗皮肤疾病和病症的药物组合物中。