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公开(公告)号：US20150094377A1
公开(公告)日：2015-04-02
申请号：US14561938
申请日：2014-12-05
Applicant: Myriad Genetics, Inc.
Inventor： Kirsten Timms , Brian Allen , Anne-Renee Hartman
IPC: C12Q1/68 , A61K31/138
CPC classification number: C12Q1/6886 , A61K31/138 , C12Q2600/156 , C12Q2600/16 , G01N33/57415 , G01N33/57449 , G16B20/00 , G16B30/00
Abstract: The invention generally relates to a molecular classification of disease predisposition and particularly to molecular markers for cancer predisposition and methods of use thereof.
Abstract translation: 本发明通常涉及疾病易感性的分子分类，特别涉及癌症易感性的分子标记及其使用方法。
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公开(公告)号：US20200087737A1
公开(公告)日：2020-03-19
申请号：US16691480
申请日：2019-11-21
Applicant: MYRIAD GENETICS, INC.
Inventor： Victor Abkevich , Alexander Gutin , Kirsten Timms , Jerry Lanchbury
IPC: C12Q1/6886 , C12Q1/6827 , G16B20/00
Abstract: This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.
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公开(公告)号：US20200010913A1
公开(公告)日：2020-01-09
申请号：US16576643
申请日：2019-09-19
Applicant: MYRIAD GENETICS, INC.
Inventor： Victor Abkevich , Alexander Gutin , Kirsten Timms , Jerry Lanchbury
IPC: C12Q1/6886
Abstract: This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.
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公开(公告)号：US20170283879A1
公开(公告)日：2017-10-05
申请号：US15433249
申请日：2017-02-15
Applicant: Myriad Genetics, Inc.
Inventor： Victor Abkevich , Kirsten Timms , Alexander Gutin , Julia Reid
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/106 , C12Q2600/156
Abstract: This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.
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公开(公告)号：US20170130263A1
公开(公告)日：2017-05-11
申请号：US15412404
申请日：2017-01-23
Applicant: Myriad Genetics, Inc.
Inventor： Alexander Gutin , Kirsten Timms , Jerry Lanchbury
CPC classification number: C12Q1/6827 , C12Q1/6858 , C12Q1/6874 , C12Q1/6883 , G16B30/00 , C12Q2535/122 , C12Q2537/143
Abstract: Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided.
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Patent Agency Ranking
公开(公告)号：US20150167100A1
公开(公告)日：2015-06-18
申请号：US14567614
申请日：2014-12-11
Applicant: MYRIAD GENETICS, INC.
Inventor： Kirsten Timms , Brian Allen , Anne-Renee Hartman
CPC classification number: C12Q1/6886 , C12Q2600/156 , G16B20/00 , G16H50/30
Abstract: The disclosure generally relates to a molecular classification of disease predisposition and particularly to molecular markers for cancer predisposition and methods of use thereof.
Abstract translation: 本公开一般涉及疾病易感性的分子分类，特别涉及用于癌症倾向的分子标记及其使用方法。
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公开(公告)号：US20230117133A1
公开(公告)日：2023-04-20
申请号：US18081603
申请日：2022-12-14
Applicant: Myriad Genetics, Inc.
Inventor： Victor Abkevich , Kirsten Timms , Alexander Gutin , Julia Reid
IPC: C12Q1/6886
Abstract: This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.
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公开(公告)号：US20220205022A1
公开(公告)日：2022-06-30
申请号：US17545611
申请日：2021-12-08
Applicant: Myriad Genetics, Inc.
Inventor： Alexander Gutin , Kirsten Timms , Jerry Lanchbury
IPC: C12Q1/6827 , G16B30/00 , C12Q1/6858 , C12Q1/6874 , C12Q1/6883
Abstract: Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided.
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公开(公告)号：US20210348240A1
公开(公告)日：2021-11-11
申请号：US17383093
申请日：2021-07-22
Applicant: Myriad Genetics, Inc.
Inventor： Kirsten Timms , Brian Allen , Anne-Renee Hartman
IPC: C12Q1/6886 , G01N33/574 , G16B20/00 , C12P19/34 , G16B20/10 , G16B20/20 , A61K31/138
Abstract: The invention generally relates to a molecular classification of disease predisposition and particularly to molecular markers for cancer predisposition and methods of use thereof.
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公开(公告)号：US20200239943A1
公开(公告)日：2020-07-30
申请号：US16815963
申请日：2020-03-11
Applicant: MYRIAD GENETICS, INC.
Inventor： Alexander Gutin , Kirsten Timms , Jerry Lanchbury
IPC: C12Q1/6827 , C12Q1/6883 , C12Q1/6858 , C12Q1/6874 , G16B30/00
Abstract: Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided.
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