公开(公告)号：US11077306B2

公开(公告)日：2021-08-03

申请号：US15418046

申请日：2017-01-27

Applicant: Medtronic, Inc.

Inventor： Nathan A. Grenz ,  Thomas J. Mullen

IPC: A61N1/368 ,  A61N1/37 ,  A61N1/362 ,  A61N1/365

Abstract: In some examples, controlling delivery of cardiac resynchronization therapy (CRT) includes storing, in a memory of an implantable medical device system and in association with each of a plurality of heart rates, at least one respective value for an interval between an atrial event and a ventricular event. Processing circuitry of the implantable medical device system may determine a heart rate of a patient and select one of the stored values for the interval between the atrial event and the ventricular event associated with the determined heart rate. The processing circuitry may further determine whether to control therapy delivery circuitry of the implantable medical device system to deliver fusion pacing or biventricular pacing, based on the selected one of the stored values for the interval between the atrial event and the ventricular event.

公开(公告)号：US20170239472A1

公开(公告)日：2017-08-24

申请号：US15589868

申请日：2017-05-08

Applicant: Medtronic, Inc.

Inventor： Xusheng Zhang ,  Jeffrey M. Gillberg ,  Thomas J. Mullen

IPC: A61N1/362 ,  A61N1/37 ,  A61N1/365 ,  A61N1/372 ,  A61N1/368

CPC classification number: A61N1/3627 ,  A61B7/00 ,  A61B7/04 ,  A61N1/36578 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3686 ,  A61N1/3702 ,  A61N1/37247 ,  A61N1/37264

Abstract: A medical device system and associated method predict a patient response to a cardiac therapy. The system includes for delivering cardiac pacing pulses to a patient's heart coupled to a cardiac sensing module and a cardiac pacing module for generating cardiac pacing pulses and controlling delivery of the pacing pulses at multiple pace parameter settings. An acoustical sensor obtains heart sound signals. A processor is enabled to receive the heart sound signals, derive a plurality of heart sound signal parameters from the heart sound signals, and determine a trend of each of the plurality of heart sound signal parameters with respect to the plurality of pace parameter settings. An external display is configured to present the trend of at least one heart sound parameter with respect to the plurality of pace parameter settings.

公开(公告)号：US20150134024A1

公开(公告)日：2015-05-14

申请号：US14537006

申请日：2014-11-10

Applicant: Medtronic, Inc.

Inventor： Aleksandre T. Sambelashvili ,  Thomas J. Mullen ,  Todd J. Sheldon

IPC: A61N1/37 ,  A61N1/365

CPC classification number: A61N1/3714 ,  A61N1/36514 ,  A61N1/36592 ,  A61N1/368 ,  A61N1/3684 ,  A61N1/371

Abstract: Cardiac resynchronization therapy (CRT) delivered to a heart of a patient may be adjusted based on detection of a surrogate indication of the intrinsic atrioventricular conduction of the heart. In some examples, the surrogate indication is determined to be a sense event of the first depolarizing ventricle of the heart within a predetermined period of time following the delivery of a fusion pacing stimulus to the later depolarizing ventricle. In some examples, the CRT is switched from a fusion pacing configuration to a biventricular pacing configuration if the surrogate indication is not detected, and the CRT is maintained in a fusion pacing configuration if the surrogate indication is detected.

Abstract translation: 可以基于检测心脏的内在房室传导的替代指示来调整输送到患者心脏的心脏再同步治疗（CRT）。 在一些示例中，在将融合起搏刺激递送到后去除极化心室之后的预定时间段内，替代指示被确定为心脏的第一去极化心室的感觉事件。 在一些示例中，如果未检测到替代指示，则CRT从融合起搏配置切换到双心室起搏配置，并且如果检测到替代指示，则CRT保持在融合起搏配置中。