公开(公告)号：US10149750B2

公开(公告)日：2018-12-11

申请号：US15044369

申请日：2016-02-16

Applicant: Neograft Technologies, Inc.

Inventor： David Wagner ,  Lorenzo Soletti ,  Mohammed S. El-Kurdi ,  Jon McGrath ,  John T. Garibotto ,  J. Christopher Flaherty

IPC: A61F2/06 ,  A61L27/18 ,  A61L27/56 ,  A61L27/58 ,  A61L27/54 ,  A61L27/04 ,  A61L27/16 ,  A61L27/34 ,  A61L27/14 ,  A61L27/36 ,  A61F2/04

Abstract: A graft device is provided comprising a flow conduit and a surrounding covering. The graft device can connect a first body space and a second body space. In one embodiment, the flow conduit is a vein, such as a harvested saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided are methods of preparing a graft device and connecting the graft device between a first body space and a second body space, such as the aorta and a location on an occluded coronary artery, distal to the occlusion.

公开(公告)号：US10065352B2

公开(公告)日：2018-09-04

申请号：US15499242

申请日：2017-04-27

Applicant: Neograft Technologies, Inc.

Inventor： Jon McGrath ,  Lorenzo Soletti ,  Mohammed S. El-Kurdi ,  William R. Wagner ,  J. Christopher Flaherty

IPC: B29C47/00 ,  D01D5/00 ,  A61F2/06 ,  A61L27/14 ,  A61L27/50 ,  D04H1/728 ,  A61L27/38

Abstract: A system for electrospinning a fiber matrix on a tubular member includes at least one nozzle, a tubular member in a spaced relationship to the at least one nozzle, and a fluid source for pressurizing a lumen of the tubular member. An electrical potential is applied between the at least one nozzle and either the tubular member or fluid from the fluid source. The electrical potential draws at least one fiber from the at least one nozzle to the tubular member.

公开(公告)号：US20150005869A1

公开(公告)日：2015-01-01

申请号：US14378263

申请日：2013-02-14

Applicant: Neograft Technologies, Inc.

Inventor： Lorenzo Soletti ,  Jon McGrath ,  Mohammed S. El-Kurdi ,  J. Christopher Flaherty

IPC: A61F2/06 ,  A61F2/07

CPC classification number: A61F2/06 ,  A61F2/064 ,  A61F2/07 ,  A61F2250/0026 ,  A61L27/50 ,  A61L27/507 ,  F04C2270/041

Abstract: A graft device including a conduit and a fiber matrix surrounding the conduit for a mammalian patient is disclosed. The graft device further includes a kink resisting element such that the graft device is configured to reduce kinking. Methods and systems for creating kink resistant graft devices are also provided.

Abstract translation: 公开了包括用于哺乳动物患者的导管和围绕导管的纤维基质的移植装置。 移植装置还包括扭结阻力元件，使得移植装置被构造成减少扭结。 还提供了用于产生耐扭结移植装置的方法和系统。