公开(公告)号：US09588046B2

公开(公告)日：2017-03-07

申请号：US14198671

申请日：2014-03-06

Applicant: OLYMPUS CORPORATION ,  OLYMPUS MEDICAL SYSTEMS CORP.

Inventor： Yasushige Ishihara ,  Hiromi Shida ,  Kei Kubo ,  Satoshi Takekoshi

IPC: G01N21/64 ,  A61B1/00 ,  A61B1/04 ,  G06T5/50

CPC classification number: G01N21/64 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/043 ,  G01N21/6456 ,  G06T5/50 ,  G06T2207/20216

Abstract: Provided is a fluorescence observation apparatus including: a fluorescence image acquisition section and a reference image acquisition section that acquire a fluorescence image and a reference image of a subject, respectively; a division image generation section that generates a division image by dividing an image based on the fluorescence image by an image based on the reference image; a display section that displays a corrected fluorescence image based on the division image; a correction processing section that applies correction processing to at least one of the reference image and the fluorescence image and/or to the division image prior to the generation of the division image or prior to the display of the corrected fluorescence image; an observation condition determination section that determines observation conditions of the subject; and a correction condition setting section that sets parameters regarding the correction processing according to the observation conditions.

Abstract translation: 本发明提供一种荧光观察装置，包括：荧光图像获取部和参考图像获取部，分别获取被检体的荧光图像和参照图像; 分割图像生成部，其通过基于所述参照图像将基于所述荧光图像的图像分割为图像来生成分割图像; 显示部，其基于所述分割图像显示校正的荧光图像; 校正处理部，其在所述分割图像的生成之前或所述校正后的荧光图像的显示之前，对所述参考图像和所述荧光图像和/或所述分割图像中的至少一个进行校正处理; 观察条件确定部，其确定被检体的观察条件; 以及校正条件设定部，其根据观察条件设定关于校正处理的参数。

公开(公告)号：US09392942B2

公开(公告)日：2016-07-19

申请号：US13952954

申请日：2013-07-29

Applicant: OLYMPUS CORPORATION

Inventor： Hiromi Shida ,  Yasushige Ishihara ,  Satoshi Takekoshi ,  Kei Kubo

IPC: G01T1/161 ,  A61B5/00 ,  A61B1/00 ,  G06T5/50 ,  G06T7/00 ,  A61B1/04

CPC classification number: A61B5/0033 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/00055 ,  A61B1/043 ,  G06T5/50 ,  G06T7/0014 ,  G06T2207/10121 ,  G06T2207/30088

Abstract: Provided is a fluoroscopy apparatus including a light source that irradiates an observation target with reference light and excitation light; a fluorescence-image generating unit that captures fluorescence emitted from the observation target X irradiated with the excitation light to generate a fluorescence image; a reference-image generating unit that captures return light returning from the observation target irradiated with the reference light to generate a reference image; an image-combining unit that superimposes the fluorescence image on the reference image to generate a combined image; a determining unit that determines whether there is a position with a luminance at or below a predetermined threshold in the reference image; and a notifying unit that, if the determining unit determines that there is a position with a luminance at or below the predetermined threshold, provides notification thereof.

Abstract translation: 本发明提供一种荧光透视设备，包括：用参考光和激发光照射观察目标的光源; 荧光图像生成单元，其捕获从所述观察对象物X发射的荧光，所述荧光被激发光照射，以产生荧光图像; 参考图像生成单元，其捕获从所述观察对象返回的照射了所述基准光的返回光，生成参照图像; 图像合成单元，其将所述荧光图像叠加在所述参考图像上以生成组合图像; 确定单元，确定参考图像中是否存在亮度在预定阈值以下的位置; 以及通知单元，如果所述确定单元确定存在具有或低于所述预定阈值的亮度的位置，则提供通知。

公开(公告)号：US12226082B2

公开(公告)日：2025-02-18

申请号：US17461446

申请日：2021-08-30

Applicant: OLYMPUS CORPORATION

Inventor： Yasuo Tanigami ,  Yusuke Otsuka ,  Noriko Kuroda ,  Yuji Kishimoto ,  Hideyuki Kasahara ,  Kazue Tanaka ,  Kunihide Kaji ,  Satoshi Takekoshi ,  Yoshitaka Honda ,  Takaaki Igarashi

IPC: A61B1/04 ,  A61B1/00 ,  A61B1/06

Abstract: A medical system can include a light source configured to generate excitation light; and a processor including a memory, the processor: controlling energy supplied to an energy device, the light source generating the excitation light to generate fluorescence from the living body tissue heat treated by the energy device; generating a fluorescence image based on an image pickup signal obtained by imaging the living body tissue; and generating a control signal that restricts energy supply to the energy device and output the control signal to the energy control apparatus when a pixel value of at least one pixel in the fluorescence image exceeds a first threshold value.

公开(公告)号：US11805977B2

公开(公告)日：2023-11-07

申请号：US16907499

申请日：2020-06-22

Applicant: OLYMPUS CORPORATION

Inventor： Masakazu Mizoguchi ,  Toshiaki Watanabe ,  Satoshi Takekoshi ,  Susumu Aono

IPC: A61B1/00 ,  A61B1/04 ,  A61B1/045 ,  A61B1/05 ,  A61B1/06

CPC classification number: A61B1/00009 ,  A61B1/00006 ,  A61B1/00045 ,  A61B1/043 ,  A61B1/045 ,  A61B1/05 ,  A61B1/0661

Abstract: An endoscope system includes a processor configured to generate a clock at predetermined timing, a light source apparatus configured to irradiate white light and excitation light in a time division manner in synchronization with the clock, and an endoscope configured to perform image pickup based on irradiation timing of the light source apparatus. The processor generates a first white light image at a first clock, generates a first fluorescent image at a second clock, generates a second white light image at a third clock, and generates a third white light image at a fourth clock and superimposes the second white light image and the first fluorescent image at the fourth clock and superimposes the third white light image and the first fluorescent image at a fifth clock.

公开(公告)号：US10951800B2

公开(公告)日：2021-03-16

申请号：US16906641

申请日：2020-06-19

Applicant: OLYMPUS CORPORATION

Inventor： Susumu Aono ,  Toshiaki Watanabe ,  Satoshi Takekoshi ,  Masakazu Mizoguchi ,  Junichi Tashiro

IPC: H04N5/225 ,  A61B1/04 ,  A61B1/045 ,  H04N5/76

Abstract: An endoscope system is provided with: a processor; a light source; and an image pickup device. The processor performs control for causing reflected light images corresponding to a predetermined period before start of the fluorescence occurrence period during the fluorescence non-occurrence period, among the reflected light images, to be recorded to the first storage medium; and, furthermore, performs control for causing the reflected light images to be recorded to the first storage medium during an after-end-of-fluorescence-occurrence period corresponding to a predetermined period with an end of the fluorescence occurrence period as a start point, and performs control for causing the reflected light images not to be recorded to the first storage medium during the fluorescence non-occurrence period after an end of the after-end-of-fluorescence-occurrence period.

公开(公告)号：US10456021B2

公开(公告)日：2019-10-29

申请号：US15964383

申请日：2018-04-27

Applicant: OLYMPUS CORPORATION

Inventor： Yuichi Shiga ,  Toshiaki Mikami ,  Koichiro Yoshino ,  Satoshi Takekoshi

IPC: A61B1/045 ,  A61B1/00 ,  H04N5/232 ,  A61B1/04 ,  H04N5/235 ,  H04N9/04 ,  A61B1/055 ,  H04N5/225 ,  H04N9/73

Abstract: An endoscope apparatus includes an optical system including a focus lens, a connector to which an interchangeable optical system is connected, an image sensor configured to output a captured image based on the optical system and the interchangeable optical system, and a processor including hardware. The processor performs a determination process of determining whether the interchangeable optical system is a known or unknown optical system, implements a first step amount determination process when the interchangeable optical system is determined to be a known optical system, and implements a second step amount determination process when the interchangeable optical system is determined to be an unknown optical system and controls the focus lens based on step amount information determined.

公开(公告)号：US09519967B2

公开(公告)日：2016-12-13

申请号：US14312956

申请日：2014-06-24

Applicant: OLYMPUS CORPORATION

Inventor： Hiromi Shida ,  Yasushige Ishihara ,  Satoshi Takekoshi ,  Kei Kubo

IPC: A61B1/00 ,  A61B1/04 ,  G02B21/16 ,  G02B23/24 ,  G06K9/46 ,  G06T7/00

CPC classification number: G06T7/0014 ,  A61B1/00009 ,  A61B1/043 ,  G02B21/16 ,  G02B23/2461 ,  G02B23/2484 ,  G06K9/46 ,  G06K2009/4666

Abstract: Fluorescence generated at a lesion is distinguished from fluorescence generated at portions other than the lesion, and thus, observation is performed by using only the fluorescence generated at the lesion. Provided is a fluorescence observation apparatus including a light radiating portion that radiates excitation light onto an examination subject; a fluorescence-distribution acquiring portion that acquires an intensity distribution of fluorescence generated at the examination subject due to irradiation with the excitation light from the light radiating portion; and a non-target-region excluding portion that, in the fluorescence-intensity distribution acquired by the fluorescence-distribution acquiring portion, excludes regions in which a spectrum in a specific wavelength band has changed due to a specific biological component whose concentration in a lesion is lower than in other portions.

Abstract translation: 在损伤处产生的荧光与病变以外的部分产生的荧光不同，因此仅使用在病变处产生的荧光进行观察。 本发明提供一种荧光观察装置，其包括将激发光照射到检查对象上的光照射部， 荧光分布获取部分，其获取由于来自所述光辐射部分的激发光的照射而在所述检查对象产生的荧光的强度分布; 以及在由荧光分布获取部获取的荧光强度分布中排除由特定生物成分在特定波长带中的光谱变化的区域的非靶区域排除部分， 低于其他部分。