Abstract:
Novel 2-phenyl ethanol derivatives of the formula
WHEREIN X is selected from the group consisting of oxygen and sulfur, Hal is halogen, R is selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms and Y is selected from the group consisting of hydrogen and acyl of an organic carboxylic acid of 1 to 18 carbon atoms and when R is alkyl, they exist in the form of racemates or optically active isomers having analgesic and anti-inflammatory activity.
WHEREIN X IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF NITRO, ACETYL AND METHYLSULFONYL, AND ITS THERAPEUTICALLY-COMPATIBLE SALTS, PROCESS OF PREPARATION OF THE PHOSPHATE ESTER AND METHODS OF THERAPY UTILIZING THE PHOSPHATE ESTER. THE SAID PHOSPHATE ESTERS HAVE AN IMPORTANT ANTIBIOTIC AND BACTERICIDAL ACTION COUPLED WITH EXCELLENT SOLUBILITY IN WATER. A PHOSPHATE ESTER SELECTED FROM THE GROUP CONSISTING OF THE 0-3-MONOPHSOPHASE OF D-THREO-1-PARA-X-PHENYL-2-DI CHLOROACETAMIDO-PROPANE-1,3-DIOL OF THE FORMULA