公开(公告)号：US20050007588A1

公开(公告)日：2005-01-13

申请号：US10487228

申请日：2003-06-27

Applicant: Giorgio Tarozzi ,  Riccardo Rivalta ,  Roberto Trebbi ,  Pierantonio Ragazzini

Inventor： Giorgio Tarozzi ,  Riccardo Rivalta ,  Roberto Trebbi ,  Pierantonio Ragazzini

IPC: G01F13/00 ,  A61J3/07 ,  B07C5/34 ,  B07C5/342 ,  B65B57/10 ,  G01N21/95 ,  G01N21/00

CPC classification number: G01N21/9508 ,  A61J3/074 ,  B07C5/3404 ,  B07C5/342 ,  B07C5/365

Abstract: In a method for optoelectronically inspecting pharmaceutical capsules (2) in a capsule filling machine (1), the pharmaceutical capsules (2) are fed in single file from a station (3) where the capsules (2) are made to a capsule (2) outfeed portion (8) of the machine (1) along a defined feed path (P) passing through an inspection station (13). In the inspection station (13), each pharmaceutical capsule (2) passes through an electromagnetic field created by coherent, polarised light radiation.

Abstract translation: 在胶囊填充机（1）中用于光电检测药物胶囊（2）的方法中，药物胶囊（2）以单个文件从胶囊（2）制成的胶囊（2） ）机器（1）的输出部分（8）沿着通过检查站（13）的限定的进给路径（P）。 在检查站（13）中，每个药物胶囊（2）通过由相干偏振光辐射产生的电磁场。

公开(公告)号：US09157784B2

公开(公告)日：2015-10-13

申请号：US13133699

申请日：2009-12-16

Applicant: Roberto Trebbi ,  Salvatore Fabrizio Consoli

Inventor： Roberto Trebbi ,  Salvatore Fabrizio Consoli

IPC: B65B1/04 ,  B65B31/00 ,  G01G17/00 ,  A61J3/07 ,  G01G7/06 ,  G01G9/00

CPC classification number: G01G17/00 ,  A61J3/074 ,  A61J2200/74 ,  G01G7/06 ,  G01G9/005

Abstract: A machine for dosing a plurality of products in capsules, or similar containers, includes a plurality of dosing units for filling the capsules with respective products and a turret arrangement that rotates intermittently and is arranged for housing and moving the capsules in sequence through the dosing units. The machine further includes a plurality of checking units, each of which is located downstream of a respective dosing unit for measuring a quantity of product dosed in the capsules by the respective dosing units.

Abstract translation: 用于对胶囊或类似容器中的多个产品进行计量的机器包括多个用于用相应产品填充胶囊的计量单元和一个间歇旋转的转台装置，并且被布置成依次通过配量单元容纳和移动胶囊 。 机器还包括多个检查单元，每个检查单元位于相应的给料单元的下游，用于测量通过相应的给料单元在胶囊中计量的产品的量。

公开(公告)号：US20080236106A1

公开(公告)日：2008-10-02

申请号：US10586874

申请日：2005-02-23

Applicant: Roberto Trebbi ,  Caterina Funaro

Inventor： Roberto Trebbi ,  Caterina Funaro

IPC: A61J3/07

CPC classification number: A61J3/072 ,  A61J3/074

Abstract: A capsule filling machine (4) for the production of hard gelatin capsules (C) of the type with lid (2) and body (1) containing pharmaceutical material, the machine (4) being of the type comprising a station (5) for feeding the capsule bodies (1) and lids (2); a dosing station (6) for filling a dose of the material into each capsule body (1); and a station (7) for closing the capsules (C) by placing each lid (2) over the respective body (1) so that their respective annular ends (2a, 1a) overlap. Between the dosing station (6) and the closing station (7) there is at least one intermediate operating station (8) for applying a sealing substance to the capsule lid and bodies in the vicinity of their ends (1a, 2a).

Abstract translation: 一种用于生产具有盖（2）和含有药物材料的主体（1）类型的硬明胶胶囊（C）的胶囊填充机（4），所述机器（4）是包括用于 喂食胶囊体（1）和盖子（2）; 用于将一定剂量的材料填充到每个胶囊主体（1）中的计量站（6）; 以及用于通过将每个盖子（2）放置在相应的主体（1）上以使它们各自的环形端部（2a，1a）重叠的方式来封闭胶囊（C）的工位（7）。 在配量站（6）和关闭站（7）之间有至少一个中间操作站（8），用于将密封物质施加到胶囊盖和其末端（1a，2a）附近的主体。

公开(公告)号：US20080145287A1

公开(公告)日：2008-06-19

申请号：US11795717

申请日：2006-02-02

Applicant: Roberto Trebbi ,  Elvio Gasperini ,  Vittoriano Marcheschi ,  Patrizia Nanni ,  Laura Marcheschi ,  Chiara Marcheschi

Inventor： Roberto Trebbi ,  Elvio Gasperini ,  Vittoriano Marcheschi ,  Patrizia Nanni ,  Laura Marcheschi ,  Chiara Marcheschi

IPC: B01J19/00

CPC classification number: B01J2/16

Abstract: A system (1) for the treatment of powdered material, in particular pharmaceutical powders, comprising, with the possibility of suitable connection between them using pipe means (4), at least a first operating unit (2) designed for mixing the powdered material with other substances to obtain a predetermined mixture, and at least a second operating unit (3) designed for subjecting the mixture to a fluid bed type treatment. The first unit (2) is supported in such a way that it is mobile relative to the second unit (3); there being means (8, 7, 13) for supporting and moving the first unit (2), for moving the first unit (2) alternatively in a predetermined direction (F) relative to the second unit (3), between a first and a second operating position (A, B).

Abstract translation: 一种用于处理粉末材料，特别是药物粉末的系统（1），其包括可能使用管道装置（4）在它们之间适当连接的至少第一操作单元（2），所述第一操作单元（2）被设计用于将粉末材料与 其他物质以获得预定的混合物，以及至少第二操作单元（3），其设计用于使混合物进行流化床型处理。 第一单元（2）以相对于第二单元（3）移动的方式被支撑; 存在用于支撑和移动第一单元（2）的装置（8,7,13），用于相对于第二单元（3）在预定方向（F）上交替地移动第一单元（2），第一单元 第二操作位置（A，B）。

公开(公告)号：US20070184143A1

公开(公告)日：2007-08-09

申请号：US11578969

申请日：2006-02-02

Applicant: Fabriano Ferrini ,  Roberto Trebbi

Inventor： Fabriano Ferrini ,  Roberto Trebbi

IPC: B30B11/08

CPC classification number: B30B15/32 ,  B30B11/08

Abstract: A tablet press machine (1) comprises a covering structure (100) enclosing in a delimited space a rotary turret (T) for the production of tablets (C); hopper means (2) for containing pharmaceutical material (M) in powder or granular form to be pressed; rotary disc means (3, 5, 6) equipped with matrices (4) designed to contain defined quantities or doses of the pharmaceutical material (M) fed to them by the hopper means (2); reciprocating punch means (7; 7a, 7b) for compressing the doses inside the matrices (4); at least a first and a second station (Z1, Z2) for completing the tablets (C) formed in respective first and second forming lines (A1, A2); the first and second completing stations (Z1, Z2) are positioned at a defined angular interval from each other on the turret (T); the machine (1) further comprises a single outfeed station (Z3) outside the structure (100) where the tablets (C) are made by the first and second forming lines (A1, A2); and conveyor means (8) coupled with the turret (T) and defining a channel for feeding the tablets (C) formed in the first line (A1) and completed in the first completing station (Z1) to the outfeed station (Z3) along a path (P) running parallel to and alongside the second line (A2).

Abstract translation: 一种压片机（1）包括一封闭结构（100），该覆盖结构（100）包围在限定空间中，用于生产片剂（C）的旋转转塔（T）; 用于容纳待压制的粉末或颗粒形式的药物材料（M）的料斗装置（2） 旋转盘装置（3,5,6）装备有设计成容纳通过料斗装置（2）供给给它们的限定数量或剂量的药物材料（M）的基质（4）; 用于压缩基质（4）内的剂量的往复冲击装置（7; 7a，7b）; 至少第一和第二工位（Z 1，Z 2），用于完成在相应的第一和第二成形线（A 1，A 2）中形成的片剂（C）; 第一和第二完成站（Z 1，Z 2）在转台（T）上彼此定义成角度间隔; 机器（1）还包括在结构（100）外部的单个出料站（Z 3），其中片剂（C）由第一和第二成形线（A 1，A 2）制成; 和传送装置（8），其与所述转台（T）联接并且限定用于将形成在所述第一线路（A 1）中的并且在所述第一完成站点（Z 1）中完成的所述片剂（C）馈送到所述出口站 3）沿着平行于并与第二线（A 2）并行的路径（P）。

公开(公告)号：US20060147573A1

公开(公告)日：2006-07-06

申请号：US10546272

申请日：2005-01-06

Applicant: Sauro Rossi ,  Roberto Trebbi

Inventor： Sauro Rossi ,  Roberto Trebbi

IPC: B30B11/10

CPC classification number: B30B11/08

Abstract: A tablet press (1) of the type with a rotary turret (3) for the production of tablets comprises a hopper (2) containing the pharmaceutical product in powder or granular form to be compressed; a rotary disc (4) equipped with matrices (5) designed to contain defined quantities of the pharmaceutical product fed to them by the hopper (2); reciprocating punches (8, 9) for compressing the powdered product and constituting a plurality of compressing operating stations (10); at least one set (A) f operating stations (10a) having a modified structure to inhibit operation, each modified structure station (10a) comprising barrier means (11) designed to be fitted at the matrices (5) in such a way as to prevent the passage of the product from the hopper (2) to the matrices (5), and opposing elastic means (12) designed to be coupled to, and act in conjunction with, the reciprocating punches (8, 9) and with the barrier means (11) in order to simulate the presence of powdered product.

Abstract translation: 具有用于制备片剂的旋转转台（3）的类型的压片机（1）包括含有要压缩的粉末或颗粒形式的药物产品的料斗（2） 装备有矩阵（5）的旋转盘（4），其设计成容纳由料斗（2）供给到其中的限定量的药物产品; 用于压缩粉末产品并构成多个压缩操作站（10）的往复冲头（8,9）; 至少一组（A）f操作站（10a）具有修改的结构以禁止操作，每个修改的结构站（10a）包括被设计为安装在矩阵（5）处的阻挡装置（11） 防止产品从料斗（2）通过到基质（5）和相对的弹性装置（12），该弹性装置被设计成与往复式冲头（8,9）结合并与其结合 意味着（11），以模拟粉状产品的存在。

公开(公告)号：US20060124053A1

公开(公告)日：2006-06-15

申请号：US10542954

申请日：2004-02-03

Applicant: Roberto Trebbi

Inventor： Roberto Trebbi

IPC: A01J27/02

CPC classification number: B05B13/0257 ,  A23G3/26 ,  A61J3/005 ,  B01J2/006 ,  B01J2/12

Abstract: A machine (100) for the treatment of pharmaceutical products (P) comprises a pan (2) that revolves about an axis of rotation (X) and a dispensing unit (3) designed to disperse a coating material inside the pan (2) over a mass (M) of the products (P) located in the pan (2). The pan (2) has an opening (7) for feeding the products to be treated (P) into the pan (2), and an opening (8) for feeding the products (PT) already treated with the coating material out of the pan (2), the infeed opening (7) and the outfeed opening (8) being separate and independent of each other. A portion (K) of the inside surface of the pan (2) is equipped with at least one helical flow regulating fin (4, 5, 6) designed to facilitate inflow (F3) of the products to be treated (P) into the pan (2) during the feeding of the products (P) into the pan (2) through the infeed opening (7) when the pan (2) itself revolves in a first direction of rotation (F1), and to cause outflow (F4) of the treated products (PT) from the pan (2) during the outfeed of the treated products (PT) from the pan (2) through the outfeed opening (8) when the pan (2) itself revolves in a second direction of rotation (F2), opposite to the first direction of rotation (F1).

Abstract translation: 用于治疗药物（P）的机器（100）包括围绕旋转轴线（X）旋转的盘（2）和设计成将覆盖材料分散在盘（2）内部的涂覆材料的分配单元（3） 位于锅（2）中的产品（P）的质量（M）。 盘（2）具有用于将待处理产品（P）进给到锅（2）中的开口（7），以及用于将已经用涂层材料处理的产品（PT）进给的开口（8） 平底锅（2），进料口（7）和出料口（8）彼此分离和独立。 盘（2）的内表面的一部分（K）配备有至少一个螺旋流量调节翅片（4,5,6），其设计成便于待处理产品（P）的流入（F 3）进入 在锅（2）本身沿第一旋转方向（F 1）旋转时，通过进料口（7）将产品（P）进给到盘（2）期间的锅（2） （2）在从锅（2）通过出料口（8）出来时从处理过的产品（PT）中的处理产品（PT）的出口（F 4） 第二旋转方向（F 2），与第一旋转方向（F 1）相反。

公开(公告)号：US06866493B2

公开(公告)日：2005-03-15

申请号：US10240727

申请日：2002-02-07

Applicant: Roberto Trebbi ,  Hans Kramer

Inventor： Roberto Trebbi ,  Hans Kramer

IPC: A61J3/06 ,  A61K9/20 ,  B30B11/08 ,  B30B15/00 ,  F21S8/02 ,  F21S8/04 ,  F21V7/10 ,  F21V7/22 ,  F21V17/10 ,  B29C43/08 ,  B30B11/10

CPC classification number: B30B15/0082 ,  B29C2043/3283 ,  B29C2043/3477 ,  B30B11/08 ,  F21S8/02 ,  F21S8/04 ,  F21V7/10 ,  F21V7/22

Abstract: A tablet press machine (100) comprises: a hopper (1) for feeding a powder or granular product (2) to a first disc (3a) that rotates about an axis (X) and is equipped with evenly distributed holes or dies (3); a second and third disc (4, 6) that are positioned above and below the first disc (3a), respectively, rotate about the axis (X) and support respective pluralities of upper and lower reciprocating punches (5, 7). The punches (5, 7) are driven towards and away from each other when they are aligned with the dies (3) in such a way as to compress the product (2). Each of the punches (5, 7) comprises a cylindrical shank (8), one end of which is equipped with a working head (10) and sealed protection means (11) acting on the cylindrical shank (8) itself. The sealed protection means (11) comprise, for each punch (5, 7), a concertinaed sleeve (12) covering the cylindrical shank (8) and having an annular portion (13) constituting its far end relative to the working head (10), forming an annular seal and providing also a removable element used to attach support means (14) that protrude from the respective disc (4, 6). The near end (15) of each concertinaed sleeve (12) relative to the working head (10) presents an enlarged annular portion (16) that engages with a matching annular groove (17) in the cylindrical shank (8) to provide a tight seal.

Abstract translation: 压片机（100）包括：料斗（1），用于将粉末或颗粒状产品（2）输送到围绕轴线（X）旋转并且具有均匀分布的孔或模具（3）的第一盘（3a） ）; 分别位于第一盘（3a）上方和下方的第二和第三盘（4,6）围绕轴线（X）旋转并支撑相应的多个上下往复冲击锤（5,7）。 当冲头（5,7）与模具（3）对齐时，冲头（5,7）彼此朝向和远离地被驱动，以便压缩产品（2）。 每个冲头（5,7）包括圆柱形柄（8），其一端装备有工作头（10）和作用在圆柱柄（8）本身上的密封保护装置（11）。 对于每个冲头（5,7），密封保护装置（11）包括覆盖圆柱形柄（8）并且具有相对于工作头（10）构成其远端的环形部分（13）的伸缩套筒（12） ），形成环形密封件并且还提供用于附接从相应的盘（4,6）突出的支撑装置（14）的可移除元件。 每个伸缩套筒（12）相对于工作头（10）的近端（15）呈现一个扩大的环形部分（16），该环形部分与圆柱形柄部（8）中匹配的环形槽（17）接合，以提供紧密 密封。

公开(公告)号：US06834475B2

公开(公告)日：2004-12-28

申请号：US10480804

申请日：2003-12-19

Applicant: Roberto Trebbi ,  Salvatore Fabrizio Consoli

Inventor： Roberto Trebbi ,  Salvatore Fabrizio Consoli

IPC: B65B110

CPC classification number: A61J3/074 ,  B65B43/60 ,  Y10S53/90

Abstract: A capsule filling machine (1) for the production of hard gelatine capsules (C) of the type with a capsule lid and a capsule body and containing a product, preferably a pharmaceutical product, comprises at least a first station (2), rotating with a stepping motion, for supporting and moving at least one capsule body (3) to a second station (4) for feeding and dosing the product, the second station (4) rotating with a stepping motion synchrozised with that of the first station (2) and having at least one cylindrical hole (5) containing a dose (6) of the product; between the first station (2) and the second station (4) there being slide means (7) for supporting and moving the capsule body (3) between a first operating position, in which the capsule body (3) is distanced from a lower end (5a) of the cylindrical hole (5), and a second operating position, in which the capsule body (3) is exactly below the lower end (5a) of the cylindrical hole (5), allowing the dose of product (6) to be released into the capsule body (3); the slide means (7) comprising a first and a second support (8, 9) operating in conjunction with one another, the first support (8) being carried by the first station (2), rotating and supporting a capsule body (3); the second support (9) being carried by the second station (4), rotating and, in the first operating position, located below the end (5a) of the cylindrical hole (5) to close the end (5a); there also being drive means (10) acting on at least the first support (8) to move the first support (8) towards the second support (9) with both radial and transversal motion until the first support (8) gradually makes contact with the second support (9), with a consequent thrust by the first support (8) on the second support (9) pushing the second support (9) back away from the first operating position to the second operationg position, allowing the dose (6) to be released into the capsule body (3).

公开(公告)号：US06539686B1

公开(公告)日：2003-04-01

申请号：US09868772

申请日：2001-06-21

Applicant: Roberto Trebbi

Inventor： Roberto Trebbi

IPC: B65B5700

CPC classification number: A61J3/074 ,  B65B35/58 ,  Y10S53/90

Abstract: Respective secondary thrusters (70, 71) are added to the primary horizontal thruster (7) and primary vertical thruster (12) of a guiding device of the known type and the guide channel (6) is provided with dimensions such that the steps of guiding and feeding the capsule (C) are performed with minor successive displacements of the said capsule (C). The primary vertical thruster (12) operates, in a position distant from the sleeve (13) of the capping machine so as to allow discarding and free removal of the defective capsules (C) which have a double lid (C2) or the capsule parts which reach this thruster. The last section (206) of the guide channel (6) inside which the secondary vertical thruster (71) operates, has a width slightly smaller than that of the upstream section (106) of the said channel so as to retain firmly the end of the defective capsule (C) having lids (C2) on opposite ends of a base (C1). Such a defective capsule (C), which is arranged horizontally or inclined by the primary horizontal thruster (7), is then acted on by the tip (112) of the primary vertical thruster (12) and by a face (171) of the secondary vertical thruster (71) which discard this defective capsule (C) from the bottom of the guide channel (6). On the other hand, a capsule (C) correctly fitted with a lid (C2) and oriented vertically by the primary vertical thruster (12) remains inside the guide channel (6), is then displaced inside the latter by the secondary horizontal thruster (70) and then a leading face (271) of the secondary vertical thruster (71) acts on this capsule and accompanies the said capsule (C) during the complete stroke for insertion inside the sleeve (13) of the capping machine.

Abstract translation: 相应的次级推进器（70,71）被加入到已知类型的导向装置的主水平推进器（7）和初级垂直推进器（12）中，并且导向通道（6）设置有尺寸，使得引导步骤 并且进行胶囊（C）的进给，其中所述胶囊（C）的次要连续位移。 主垂直推进器（12）在远离封盖机的套筒（13）的位置操作，以便能够丢弃和自由移除具有双盖（C2）或胶囊部件的缺陷胶囊（C） 到达这个推进器。 第二纵向推进器（71）所在的引导通道（6）的最后一个部分（206）的宽度略小于所述通道的上游部分（106）的宽度，以便牢固地保持 所述缺陷胶囊（C）在基座（C1）的相对端具有盖（C2）。 这种由主水平推进器（7）水平或倾斜布置的缺陷胶囊（C）然后由主垂直推进器（12）的尖端（112）和由主垂直推进器（12）的表面（171）起作用 二次垂直推进器（71），其从导向通道（6）的底部丢弃该缺陷胶囊（C）。 另一方面，由主要垂直推进器（12）正确地装配有盖（C2）并垂直取向的胶囊（C）保留在引导通道（6）内，然后通过第二水平推进器（ 70），然后第二垂直推进器（71）的引导面（271）作用在该胶囊上，并在整个冲程期间伴随着所述胶囊（C），以插入到封盖机的套筒（13）内。