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    Capsule filling machine and method for producing hard gelatin capsules
    1.
    发明授权
    Capsule filling machine and method for producing hard gelatin capsules 失效
    胶囊灌装机及其制备方法

    公开(公告)号：US07677016B2

    公开(公告)日：2010-03-16

    申请号：US10568506

    申请日：2005-05-09

    Applicant: Roberto Trebbi

    Inventor： Roberto Trebbi

    IPC: B65B47/00

    CPC classification number: A61J3/074 ,  B65B1/366 ,  B65B1/48

    Abstract: A capsule filling machine (100) for the production of hard gelatin capsules (C) of the type with lid (3) and body (2) containing a quantity (1) of pharmaceutical material comprises a rotary turret or carousel (15) which defines at least one capsule (C) handling line (L) and on which the following are positioned, one after the other: at least one station (6) for feeding empty capsules (C); at least one opening station (20) where the capsule bodies (2) are separated from the lids (3) to form two separate rows of capsule bodies (2) and lids (3); at least one station (7) for feeding and dosing the quantities (1) of pharmaceutical material to be filled into the capsule bodies (2); and at least one station (8) for closing the capsules (C) by placing a lid (3) over each respective body (2); the machine (100) also comprises means (9) for detecting and volumetrically checking the quantity (1) of pharmaceutical material filled into each capsule body (2), the detecting and checking means (9) comprise transducer means (5) for measuring the volume of said quantities (1) before they are filled into the capsule bodies (2).

    Abstract translation: 用于生产具有盖（3）和包含数量（1）药物材料的盖子（3）和主体（2）的类型的硬明胶胶囊（C）的胶囊填充机（100）包括旋转转盘或转盘（15），其定义 至少一个胶囊（C）处理线（L），并且其上定位有下列物品：至少一个用于供给空胶囊（C）的工位（6）; 至少一个开口站（20），其中所述胶囊主体（2）与所述盖（3）分离以形成两个独立的胶囊体（2）和盖（3）排; 至少一个站（7），用于将要填充的药物材料的数量（1）进料和给药到胶囊体（2）中; 以及至少一个用于通过在每个相应的主体（2）上放置盖子（3）来关闭胶囊（C）的工位（8）。 机器（100）还包括用于检测和体积检查填充到每个胶囊主体（2）中的药物材料的量（1）的装置（9），检测和检查装置（9）包括用于测量 所述量（1）的体积在它们被装入胶囊体（2）之前。

    Tablet press machine
    3.
    发明授权
    Tablet press machine 有权
    压片机

    公开(公告)号：US06997691B2

    公开(公告)日：2006-02-14

    申请号：US10468157

    申请日：2002-03-12

    Applicant: Roberto Trebbi ,  Hans Kramer

    Inventor： Roberto Trebbi ,  Hans Kramer

    IPC: B29C43/08

    CPC classification number: B30B15/0082 ,  B30B11/08 ,  B30B15/0023 ,  B30B15/028

    Abstract: A tablet press machine (1) includes a fixed casing (2) which houses a compression assembly (3) comprising a power-driven rotor (4) that rotates about an axis (5), the rotor including a matrix disc (6) and another two discs (7, 8) on both sides of it, mounting two sets of reciprocating punches (9, 10) opposite and aligned with each other in pairs. The matrix disc (6) has a plurality of through matrixes (11) where the reciprocating punches (9, 10) forming each pair are mounted in such a way as to delimit between them an empty space (12) of variably size designed to contain a dosed quantity of powder to be compressed. Two sets of cams (13, 14) are associated with the compression assembly (3) and, as the rotor (4) rotates, impart on the punches (9, 10) a driving motion which moves them cyclically towards and away from each other in such a way as to compress the powder contained in the matrix (11) in the matrix disc (6). The casing (2) comprises, inside it, sealed separating means (15; 18, 19, 21, 22) desigend to delimit separate spaces (16, 17, 20) for housing the compression assembly (3) and the sets of cams (13; 14) in order to prevent the powdered product from contaminating the cams.

    Abstract translation: 压片机（1）包括固定壳体（2），该固定壳体容纳包括围绕轴线（5）旋转的动力转子（4）的压缩组件（3），所述转子包括矩阵盘（6）和 在其两侧的另外两个盘（7,8）上，安装了两组相互对准并成对对准的往复式冲压件（9,10）。 矩阵盘（6）具有多个通过矩阵（11），其中形成每一对的往复式冲压件（9,10）以这样的方式安装，以便在它们之间限定设计成包含的可变尺寸的空间（12） 一定量的待压缩的粉末。 两组凸轮（13,14）与压缩组件（3）相关联，并且当转子（4）旋转时，赋予冲头（9,10）一个驱动运动，这些驱动运动使它们周期性地向彼此移动 以这种方式压缩基质盘（6）中的基质（11）中所含的粉末。 壳体（2）内部包括密封的分离装置（15; 18,19,21,22），用于限定用于容纳压缩组件（3）和凸轮组的分隔空间（16,17,20） 13; 14），以防止粉末产品污染凸轮。

    Granulator device
    5.
    发明授权
    Granulator device 有权
    造粒机装置

    公开(公告)号：US07922798B2

    公开(公告)日：2011-04-12

    申请号：US11910398

    申请日：2006-04-07

    Applicant: Salvatore Fabrizio Consoli ,  Andrea Nora ,  Roberto Trebbi

    Inventor： Salvatore Fabrizio Consoli ,  Andrea Nora ,  Roberto Trebbi

    IPC: B01D46/04

    CPC classification number: B01J2/16

    Abstract: A granulator device (1) for the treatment of powdered material, in particular pharmaceutical powdered material, comprises a substantially cylindrical container (2), in which there is a chamber (4) for treatment of the powdered material using a fluid flow fed into the chamber (4); filtering means (5) for filtering the inside of the chamber (4), the filtering means (5) being located in the chamber (4) and comprising at least one filter (5) with a cylindrical metal mesh filtering wall (6); and means (P) for cleaning the filtering means (5) which can be activated during maintenance operations, the cleaning means comprising at least one element (7) rotating about each filter (5) and supporting diffuser means (8) designed to diffuse a service fluid on the cylindrical wall (6) in order to eliminate any impurities trapped in the filter (5) wall (6); the cleaning means (P) also comprise means (9) for temporarily opening at least one portion (10) of the filter (5) to allow the service fluid to flow out of the filter (5) together with the impurities.

    Abstract translation: 用于处理粉末材料，特别是药物粉末材料的造粒装置（1）包括基本上为圆柱形的容器（2），其中存在用于使用供给到粉末材料的流体流来处理粉末材料的室（4） 室（4）; 过滤装置（5），用于过滤室（4）的内部，过滤装置（5）位于室（4）中，并且包括至少一个具有圆柱形金属网过滤壁（6）的过滤器（5）; 以及用于清洁过滤装置（5）的装置（P），所述清洁装置可在维护操作期间被启动，所述清洁装置包括围绕每个过滤器（5）旋转的至少一个元件（7）和支撑扩散装置（8） 为了消除捕获在过滤器（5）壁（6）中的任何杂质，在圆筒壁（6）上的工作流体; 清洁装置（P）还包括用于临时打开过滤器（5）的至少一部分（10）的装置（9），以允许使用流体与杂质一起流出过滤器（5）。

    Intermittent Motion Capsule Filling Machine
    6.
    发明申请
    Intermittent Motion Capsule Filling Machine 失效
    间歇运动胶囊灌装机

    公开(公告)号：US20080209858A1

    公开(公告)日：2008-09-04

    申请号：US11996481

    申请日：2006-07-24

    Applicant: Roberto Trebbi

    Inventor： Roberto Trebbi

    IPC: B65B1/00

    CPC classification number: A61J3/074

    Abstract: A capsule filling machine (10) for producing hard gelatin capsules (C) of the type with lid and body (3, 4) containing particles (12) of pharmaceutical material, in particular microtablets (12) or pellets comprises a rotary carousel (2) mounting a plurality of slide units (5) for holding and handling the capsules (C) in order to open and then close the capsules (C) by first separating and then pairing the capsule lids (3) and bodies (4); and means (11) for feeding the particles (12) to the carousel (2) for filling doses of the particles (12) into the respective capsule bodies (4); the feed means (11) comprise at least one hopper (13) containing a mass of these particles (12), and roller means (14) partly immersed in said mass of particles (12) in the hopper (13); the roller means (14) having a plurality of suction recesses (15) for accommodating and retaining a predetermined number of the particles (12) drawn from the hopper (13) and then releasing the particles (12) into a series of hollow conduits (16) mounted on the carousel (2).

    Abstract translation: 一种胶囊填充机（10），其用于制造具有盖和主体（3,4）的类型的硬明胶胶囊（C），所述盖体和主体包含药物材料颗粒（12），特别是微片（12）或丸粒，包括旋转圆盘传送带 ）安装多个用于保持和处理胶囊（C）的滑动单元（5），以通过首先分离胶囊盖（3）和主体（4）来打开然后关闭胶囊（C）; 以及用于将颗粒（12）馈送到转盘（2）以将颗粒（12）的剂量填充到各个胶囊体（4）中的装置（11）; 进料装置（11）包括至少一个包含这些颗粒（12）的料斗（13），以及部分地浸入料斗（13）中的所述颗粒（12）中的滚筒装置（14）。 辊装置（14）具有多个吸入凹部（15），用于容纳并保持从料斗（13）拉出的预定数量的颗粒（12），然后将颗粒（12）释放成一系列中空导管（ 16）安装在转盘（2）上。

    Machine for the treatment of pharmaceutical products
    7.
    发明授权
    Machine for the treatment of pharmaceutical products 失效
    机械用于治疗药品

    公开(公告)号：US07395777B2

    公开(公告)日：2008-07-08

    申请号：US10542954

    申请日：2004-02-03

    Applicant: Roberto Trebbi

    Inventor： Roberto Trebbi

    IPC: B05C3/08 ,  B05C5/02

    CPC classification number: B05B13/0257 ,  A23G3/26 ,  A61J3/005 ,  B01J2/006 ,  B01J2/12

    Abstract: A machine (100) for the treatment of pharmaceutical products (P) comprises a pan (2) that revolves about an axis of rotation (X) and a dispensing unit (3) designed to disperse a coating material inside the pan (2) over a mass (M) of the products (P) located in the pan (2). The pan (2) has an opening (7) for feeding the products to be treated (P) into the pan (2), and an opening (8) for feeding the products (PT) already treated with the coating material out of the pan (2), the infeed opening (7) and the outfeed opening (8) being separate and independent of each other. A portion (K) of the inside surface of the pan (2) is equipped with at least one helical flow regulating fin (4, 5, 6) designed to facilitate inflow (F3) of the products to be treated (P) into the pan (2) during the feeding of the products (P) into the pan (2) through the infeed opening (7) when the pan (2) itself revolves in a first direction of rotation (FI), and to cause outflow (F4) of the treated products (PT) from the pan (2) during the outfeed of the treated products (PT) from the pan (2) through the outfeed opening (8) when the pan (2) itself revolves in a second direction of rotation (F2), opposite to the first direction of rotation (F1).

    Abstract translation: 用于治疗药物（P）的机器（100）包括围绕旋转轴线（X）旋转的盘（2）和设计成将覆盖材料分散在盘（2）内部的涂覆材料的分配单元（3） 位于锅（2）中的产品（P）的质量（M）。 盘（2）具有用于将待处理产品（P）进给到锅（2）中的开口（7），以及用于将已经用涂层材料处理的产品（PT）进给的开口（8） 平底锅（2），进料口（7）和出料口（8）彼此分离和独立。 盘（2）的内表面的一部分（K）配备有至少一个螺旋流量调节翅片（4,5,6），其设计成便于待处理产品（P）的流入（F 3）进入 当盘（2）本身沿第一旋转方向（FI）旋转并且引起流出（F）时，通过进料口（7）将产品（P）进给到盘（2）期间的锅（2） 在锅（2）本身在一秒钟内旋转时，处理过的产品（PT）从锅（2）通过出料口（8）出来时从锅（2）处理的处理产品（PT） 旋转方向（F 2），与第一旋转方向（F 1）相反。

    Unit for checking the dosing of pharmaceutical material in a capsule filling machine
    8.
    发明授权
    Unit for checking the dosing of pharmaceutical material in a capsule filling machine 失效
    用于检查胶囊灌装机中药物剂量的单位

    公开(公告)号：US06837280B2

    公开(公告)日：2005-01-04

    申请号：US10486914

    申请日：2003-06-27

    Applicant: Pierantonio Ragazzini ,  Elvio Gasperini ,  Roberto Trebbi ,  Enrico Zerbinati ,  Riccardo Rivalta ,  Nicola Gandolfi ,  Giorgio Tarozzi

    Inventor： Pierantonio Ragazzini ,  Elvio Gasperini ,  Roberto Trebbi ,  Enrico Zerbinati ,  Riccardo Rivalta ,  Nicola Gandolfi ,  Giorgio Tarozzi

    IPC: B65B3/12 ,  A61J3/07 ,  B65B1/38 ,  B65B3/28 ,  B65B3/32 ,  B65B1/04

    CPC classification number: A61J3/074 ,  A61J2200/74 ,  B65B1/38 ,  B65B3/32

    Abstract: A unit (6) for checking the dosing of pharmaceutical material (M) in a capsule filling machine (1) for the production of capsules (CF) of the type with a capsule lid (C) and a capsule body (F), the machine (1) comprising a fixed structure (15) fitted with a rotary drum (2) for supporting a plurality of capsules (CF) on its edge, opening each capsule (CF) by separating the capsule lid (C) from the capsule body (F), filling the capsule body (F) with a dose of material (M), then closing the capsule body (F) again with the relative capsule lid (C); the rotary drum (2) having a tank (5) containing the pharmaceutical material (M) and supporting a plurality of doser elements (3), each comprising at least one piston (8) sliding inside a hollow cylinder (4) to pick up and compress a dose (DS) of material (M) from the tank (5) and discharge it into a capsule body (F) of a capsule (CF). The unit (6) comprises sensor means (9) attached to each piston (8) for detecting a piston (8) thrust value (V; V1) on the dose (DS) and transmitter means (10) connected to the sensor means (9) for transmitting the value (V; V1) to a receiver element (11; 41) by the telemetric transmission of a relative signal (S; S1), said receiver element (11; 41) being fixed on the machine (1) in at least one zone (P1; P2) of the fixed structure (15). Power supply means (12, 14a) are also provided for cyclically activating the sensor means (9) and the transmitter means (10) during drum (2) rotation.

    Abstract translation: 一种用于在用于制造具有胶囊盖（C）和胶囊主体（F）的胶囊（CF）的胶囊填充机（1）中用于检查药物材料（M）的剂量的单元（6）， 机器（1）包括装配有用于在其边缘上支撑多个胶囊（CF）的旋转鼓（2）的固定结构（15），通过将胶囊盖（C）与胶囊主体 （F），用一定量的材料（M）填充胶囊主体（F），然后用相对的胶囊盖（C）再次封闭胶囊主体（F）; 所述旋转鼓（2）具有容纳所述药物材料（M）并且支撑多个加药器元件（3）的罐（5），每个所述加药器元件（3）包括在中空圆柱体（4）内滑动的至少一个活塞（8） 并且从所述罐（5）压缩材料（M）的剂量（DS）并将其排出到胶囊（CF）的胶囊体（F）中。 单元（6）包括附接到每个活塞（8）的传感器装置（9），用于检测剂量（DS）上的活塞（8）推力值（V; V1）和连接到传感器装置的传送装置（10） 9），用于通过相对信号（S; S1）的遥测传输将值（V; V1）发送到接收器元件（11; 41），所述接收器元件（11; 41）固定在机器（1）上， 在所述固定结构（15）的至少一个区域（P1; P2）中。 还提供电源装置（12,14a），用于在鼓（2）旋转期间循环地启动传感器装置（9）和发射器装置（10）。

    ROTARY PAN
    9.
    发明申请
    ROTARY PAN 审中-公开
    旋转盘

    公开(公告)号：US20120186516A1

    公开(公告)日：2012-07-26

    申请号：US13367860

    申请日：2012-02-07

    Applicant: NICOLA GANDOLFI ,  ROBERTO TREBBI

    Inventor： NICOLA GANDOLFI ,  ROBERTO TREBBI

    IPC: B05C13/00

    CPC classification number: B01J2/14 ,  B01J2/12

    Abstract: Described is a rotary pan (1) of the type comprising a central hollow cylindrical body (3) with end portions (4, 4′) shaped substantially like truncated cones, and mixing/deflecting means (7) attached to at least one inside surface of the pan (1) itself; the peripheral inside cylindrical surface (5) of the hollow body (3) comprises an extended zone (A) defined by a uniform distribution of through holes (6) and at least one zone (B) within the zone (A) forming an area by which the mixing/deflecting means (7) are attached or fixed to the peripheral surface (5).

    Abstract translation: 描述了一种旋转盘（1），其包括具有基本上类似截锥体的端部（4,4'）的中心中空圆柱体（3），以及连接到至少一个内表面的混合/偏转装置（7） 的锅（1）本身; 中空体（3）的周边圆柱形表面（5）包括通过通孔（6）的均匀分布和区域（A）内的至少一个区域（B）限定的延伸区域（A），形成区域 混合/偏转装置（7）通过该装置固定或固定到周边表面（5）。

    MACHINE AND METHOD FOR FILLING AND CHECKING CAPSULES
    10.
    发明申请
    MACHINE AND METHOD FOR FILLING AND CHECKING CAPSULES 有权
    用于填充和检查胶囊的机器和方法

    公开(公告)号：US20110277871A1

    公开(公告)日：2011-11-17

    申请号：US13133699

    申请日：2009-12-16

    Applicant: Roberto Trebbi ,  Salvatore Fabrizio Consoli

    Inventor： Roberto Trebbi ,  Salvatore Fabrizio Consoli

    IPC: B65B1/04 ,  B65B31/00

    CPC classification number: G01G17/00 ,  A61J3/074 ,  A61J2200/74 ,  G01G7/06 ,  G01G9/005

    Abstract: A machine for dosing a plurality of products in capsules, or similar containers, includes a plurality of dosing units for filling the capsules with respective products and a turret arrangement that rotates intermittently and is arranged for housing and moving the capsules in sequence through the dosing units. The machine further includes a plurality of checking units, each of which is located downstream of a respective dosing unit for measuring a quantity of product dosed in the capsules by the respective dosing units.

    Abstract translation: 用于对胶囊或类似容器中的多个产品进行计量的机器包括多个用于用相应产品填充胶囊的计量单元和一个间歇旋转的转台装置，并且被布置成依次通过配量单元容纳和移动胶囊 。 机器还包括多个检查单元，每个检查单元位于相应的给料单元的下游，用于测量通过相应的给料单元在胶囊中计量的产品的量。

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