公开(公告)号：US06997691B2

公开(公告)日：2006-02-14

申请号：US10468157

申请日：2002-03-12

Applicant: Roberto Trebbi ,  Hans Kramer

Inventor： Roberto Trebbi ,  Hans Kramer

IPC: B29C43/08

CPC classification number: B30B15/0082 ,  B30B11/08 ,  B30B15/0023 ,  B30B15/028

Abstract: A tablet press machine (1) includes a fixed casing (2) which houses a compression assembly (3) comprising a power-driven rotor (4) that rotates about an axis (5), the rotor including a matrix disc (6) and another two discs (7, 8) on both sides of it, mounting two sets of reciprocating punches (9, 10) opposite and aligned with each other in pairs. The matrix disc (6) has a plurality of through matrixes (11) where the reciprocating punches (9, 10) forming each pair are mounted in such a way as to delimit between them an empty space (12) of variably size designed to contain a dosed quantity of powder to be compressed. Two sets of cams (13, 14) are associated with the compression assembly (3) and, as the rotor (4) rotates, impart on the punches (9, 10) a driving motion which moves them cyclically towards and away from each other in such a way as to compress the powder contained in the matrix (11) in the matrix disc (6). The casing (2) comprises, inside it, sealed separating means (15; 18, 19, 21, 22) desigend to delimit separate spaces (16, 17, 20) for housing the compression assembly (3) and the sets of cams (13; 14) in order to prevent the powdered product from contaminating the cams.

Abstract translation: 压片机（1）包括固定壳体（2），该固定壳体容纳包括围绕轴线（5）旋转的动力转子（4）的压缩组件（3），所述转子包括矩阵盘（6）和 在其两侧的另外两个盘（7,8）上，安装了两组相互对准并成对对准的往复式冲压件（9,10）。 矩阵盘（6）具有多个通过矩阵（11），其中形成每一对的往复式冲压件（9,10）以这样的方式安装，以便在它们之间限定设计成包含的可变尺寸的空间（12） 一定量的待压缩的粉末。 两组凸轮（13,14）与压缩组件（3）相关联，并且当转子（4）旋转时，赋予冲头（9,10）一个驱动运动，这些驱动运动使它们周期性地向彼此移动 以这种方式压缩基质盘（6）中的基质（11）中所含的粉末。 壳体（2）内部包括密封的分离装置（15; 18,19,21,22），用于限定用于容纳压缩组件（3）和凸轮组的分隔空间（16,17,20） 13; 14），以防止粉末产品污染凸轮。

公开(公告)号：US06866493B2

公开(公告)日：2005-03-15

申请号：US10240727

申请日：2002-02-07

Applicant: Roberto Trebbi ,  Hans Kramer

Inventor： Roberto Trebbi ,  Hans Kramer

IPC: A61J3/06 ,  A61K9/20 ,  B30B11/08 ,  B30B15/00 ,  F21S8/02 ,  F21S8/04 ,  F21V7/10 ,  F21V7/22 ,  F21V17/10 ,  B29C43/08 ,  B30B11/10

CPC classification number: B30B15/0082 ,  B29C2043/3283 ,  B29C2043/3477 ,  B30B11/08 ,  F21S8/02 ,  F21S8/04 ,  F21V7/10 ,  F21V7/22

Abstract: A tablet press machine (100) comprises: a hopper (1) for feeding a powder or granular product (2) to a first disc (3a) that rotates about an axis (X) and is equipped with evenly distributed holes or dies (3); a second and third disc (4, 6) that are positioned above and below the first disc (3a), respectively, rotate about the axis (X) and support respective pluralities of upper and lower reciprocating punches (5, 7). The punches (5, 7) are driven towards and away from each other when they are aligned with the dies (3) in such a way as to compress the product (2). Each of the punches (5, 7) comprises a cylindrical shank (8), one end of which is equipped with a working head (10) and sealed protection means (11) acting on the cylindrical shank (8) itself. The sealed protection means (11) comprise, for each punch (5, 7), a concertinaed sleeve (12) covering the cylindrical shank (8) and having an annular portion (13) constituting its far end relative to the working head (10), forming an annular seal and providing also a removable element used to attach support means (14) that protrude from the respective disc (4, 6). The near end (15) of each concertinaed sleeve (12) relative to the working head (10) presents an enlarged annular portion (16) that engages with a matching annular groove (17) in the cylindrical shank (8) to provide a tight seal.

Abstract translation: 压片机（100）包括：料斗（1），用于将粉末或颗粒状产品（2）输送到围绕轴线（X）旋转并且具有均匀分布的孔或模具（3）的第一盘（3a） ）; 分别位于第一盘（3a）上方和下方的第二和第三盘（4,6）围绕轴线（X）旋转并支撑相应的多个上下往复冲击锤（5,7）。 当冲头（5,7）与模具（3）对齐时，冲头（5,7）彼此朝向和远离地被驱动，以便压缩产品（2）。 每个冲头（5,7）包括圆柱形柄（8），其一端装备有工作头（10）和作用在圆柱柄（8）本身上的密封保护装置（11）。 对于每个冲头（5,7），密封保护装置（11）包括覆盖圆柱形柄（8）并且具有相对于工作头（10）构成其远端的环形部分（13）的伸缩套筒（12） ），形成环形密封件并且还提供用于附接从相应的盘（4,6）突出的支撑装置（14）的可移除元件。 每个伸缩套筒（12）相对于工作头（10）的近端（15）呈现一个扩大的环形部分（16），该环形部分与圆柱形柄部（8）中匹配的环形槽（17）接合，以提供紧密 密封。

公开(公告)号：US07153118B2

公开(公告)日：2006-12-26

申请号：US10912151

申请日：2004-08-06

Applicant: Roberto Trebbi ,  Hans Kramer

Inventor： Roberto Trebbi ,  Hans Kramer

IPC: B29C43/08 ,  B30B11/10

CPC classification number: B30B15/0082 ,  B29C2043/3283 ,  B29C2043/3477 ,  B30B11/08 ,  F21S8/02 ,  F21S8/04 ,  F21V7/10 ,  F21V7/22

Abstract: A tablet press machine (100) comprises: a hopper (1) for feeding a powder or granular product (2) to a first disc (3a) that rotates about an axis (X) and is equipped with evenly distributed holes or dies (3); a second and third disc (4, 6) that are positioned above and below the first disc (3a), respectively, rotate about the axis (X) and support respective pluralities of upper and lower reciprocating punches (5,7). The punches (5, 7) are driven towards and away from each other when they are aligned with the dies (3) in such a way as to compress the product (2). Each of the punches (5, 7) comprises a cylindrical shank (8), one end of which is equipped with a working head (10) and sealed protection means (11) acting on the cylindrical shank (8) itself. The sealed protection means (11) comprise, for each punch (5, 7), a concertinaed sleeve (12) covering the cylindrical shank (8) and having an annular portion (13) constituting its far end relative to the working head (10), forming an annular seal and providing also a removable element used to attach support means (14) that protrude from the respective disc (4, 6). The near end (15) of each concertinaed sleeve (12) relative to the working head (10) presents an enlarged annular portion (16) that engages with a matching annular groove (17) in the cylindrical shank (8) to provide a tight seal.

Abstract translation: 压片机（100）包括：料斗（1），用于将粉末或颗粒状产品（2）供给到围绕轴线（X）旋转并且具有均匀分布的孔或模具（X）的第一盘（3a） 3）; 分别位于第一盘（3a）上方和下方的第二和第三盘（4,6）围绕轴线（X）旋转并支撑相应的多个上下往复冲击锤（5,7）。 当冲头（5,7）与模具（3）对齐时，冲头（5,7）彼此朝向和远离地被驱动，以便压缩产品（2）。 每个冲头（5,7）包括圆柱形柄（8），其一端装备有工作头（10）和作用在圆柱柄（8）本身上的密封保护装置（11）。 对于每个冲头（5,7），密封保护装置（11）包括覆盖圆柱形柄（8）并且具有相对于工作头（10）构成其远端的环形部分（13）的伸缩套筒（12） ），形成环形密封件并且还提供用于附接从相应的盘（4,6）突出的支撑装置（14）的可移除元件。 每个伸缩套筒（12）相对于工作头（10）的近端（15）呈现一个扩大的环形部分（16），该环形部分与圆柱形柄部（8）中匹配的环形槽（17）接合，以提供紧密 密封。

公开(公告)号：US20050008730A1

公开(公告)日：2005-01-13

申请号：US10912151

申请日：2004-08-06

Applicant: Roberto Trebbi ,  Hans Kramer

Inventor： Roberto Trebbi ,  Hans Kramer

IPC: A61J3/06 ,  A61K9/20 ,  B30B11/08 ,  B30B15/00 ,  F21S8/02 ,  F21S8/04 ,  F21V7/10 ,  F21V7/22 ,  F21V17/10 ,  B30B11/10

CPC classification number: B30B15/0082 ,  B29C2043/3283 ,  B29C2043/3477 ,  B30B11/08 ,  F21S8/02 ,  F21S8/04 ,  F21V7/10 ,  F21V7/22

Abstract: A tablet press machine (100) comprises: a hopper (1) for feeding a powder or granular product (2) to a first disc (3a) that rotates about an axis (X) and is equipped with evenly distributed holes or dies (3); a second and third disc (4, 6) that are positioned above and below the first disc (3a), respectively, rotate about the axis (X) and support respective pluralities of upper and lower reciprocating punches (5,7). The punches (5, 7) are driven towards and away from each other when they are aligned with the dies (3) in such a way as to compress the product (2). Each of the punches (5, 7) comprises a cylindrical shank (8), one end of which is equipped with a working head (10) and sealed protection means (11) acting on the cylindrical shank (8) itself. The sealed protection means (11) comprise, for each punch (5, 7), a concertinaed sleeve (12) covering the cylindrical shank (8) and having an annular portion (13) constituting its far end relative to the working head (10), forming an annular seal and providing also a removable element used to attach support means (14) that protrude from the respective disc (4, 6). The near end (15) of each concertinaed sleeve (12) relative to the working head (10) presents an enlarged annular portion (16) that engages with a matching annular groove (17) in the cylindrical shank (8) to provide a tight seal.

Abstract translation: 压片机（100）包括：料斗（1），用于将粉末或颗粒状产品（2）输送到围绕轴线（X）旋转并且具有均匀分布的孔或模具（3）的第一盘（3a） ）; 分别位于第一盘（3a）上方和下方的第二和第三盘（4,6）围绕轴线（X）旋转并支撑相应的多个上下往复冲击锤（5,7）。 当冲头（5,7）与模具（3）对齐时，冲头（5,7）彼此朝向和远离地被驱动，以便压缩产品（2）。 每个冲头（5,7）包括圆柱形柄（8），其一端装备有工作头（10）和作用在圆柱柄（8）本身上的密封保护装置（11）。 对于每个冲头（5,7），密封保护装置（11）包括覆盖圆柱形柄（8）并且具有相对于工作头（10）构成其远端的环形部分（13）的伸缩套筒（12） ），形成环形密封件并且还提供用于附接从相应的盘（4,6）突出的支撑装置（14）的可移除元件。 每个伸缩套筒（12）相对于工作头（10）的近端（15）呈现一个扩大的环形部分（16），该环形部分与圆柱形柄部（8）中匹配的环形槽（17）接合，以提供紧密 密封。

公开(公告)号：US20110277871A1

公开(公告)日：2011-11-17

申请号：US13133699

申请日：2009-12-16

Applicant: Roberto Trebbi ,  Salvatore Fabrizio Consoli

Inventor： Roberto Trebbi ,  Salvatore Fabrizio Consoli

IPC: B65B1/04 ,  B65B31/00

CPC classification number: G01G17/00 ,  A61J3/074 ,  A61J2200/74 ,  G01G7/06 ,  G01G9/005

Abstract: A machine for dosing a plurality of products in capsules, or similar containers, includes a plurality of dosing units for filling the capsules with respective products and a turret arrangement that rotates intermittently and is arranged for housing and moving the capsules in sequence through the dosing units. The machine further includes a plurality of checking units, each of which is located downstream of a respective dosing unit for measuring a quantity of product dosed in the capsules by the respective dosing units.

Abstract translation: 用于对胶囊或类似容器中的多个产品进行计量的机器包括多个用于用相应产品填充胶囊的计量单元和一个间歇旋转的转台装置，并且被布置成依次通过配量单元容纳和移动胶囊 。 机器还包括多个检查单元，每个检查单元位于相应的给料单元的下游，用于测量通过相应的给料单元在胶囊中计量的产品的量。

公开(公告)号：US07534278B2

公开(公告)日：2009-05-19

申请号：US10567094

申请日：2004-08-02

Applicant: Salvatore Fabrizio Consoli ,  Andrea Nora ,  Roberto Trebbi

Inventor： Salvatore Fabrizio Consoli ,  Andrea Nora ,  Roberto Trebbi

IPC: B01D46/04

CPC classification number: B01D46/2411 ,  B01D46/0068 ,  B01D46/0082 ,  B01D2273/14 ,  B01D2275/10 ,  B01J2/00 ,  B01J2/16

Abstract: A granulator device (101) for the treatment of powdered products comprises a closed container (102) forming a chamber (103) for treatment of the products, filter elements (104, 105) projecting into the treatment chamber (103), the filter elements comprising a multi-layer filtering wall (105) through which a fluid current can pass, and powder removing parts (106; 107, 108, 109, 110) designed to diffuse at least one service fluid directed towards at least the filtering wall (105); the powder removing parts (106; 107, 108, 109, 110) having at least first diffuser nozzles (107) and at least second diffuser nozzles (108) to diffuse the service fluid so as to free the filtering wall (105) of the powders trapped in it; there also being parts (140, 142, 147) for supporting and driving the filter elements (104, 105) which can change the angle of the filter elements (104, 105) from a first operating position, in which at least the first nozzles (107) act on the filtering wall (105), to a second operating position in which the filter elements (104) are set at an angle to the first operating position to allow the second diffuser nozzles (108) to operate on the filtering wall (105).

Abstract translation: 用于处理粉末状产品的造粒装置（101）包括形成用于处理产品的室（103）的密闭容器（102），突出到处理室（103）中的过滤元件（104,105），过滤元件 包括多层过滤壁（105），流体流通过所述多层过滤壁（105），以及粉末去除部分（106; 107,108,109,110），其设计成将至少一个服务流体扩散至少至少过滤壁 ）; 所述粉末去除部分（106; 107,108,109,110）具有至少第一扩散器喷嘴（107）和至少第二扩散器喷嘴（108），以扩散所述工作流体以便释放所述过滤壁（105） 被捕获的粉末; 还存在用于支撑和驱动过滤器元件（104,105）的部件（140,142,147），其可以将过滤元件（104,105）的角度从第一操作位置改变，其中至少第一喷嘴 （107）作用在过滤壁（105）上的第二操作位置，其中过滤元件（104）被设置成与第一操作位置成一定角度，以允许第二扩散器喷嘴（108）在过滤壁 （105）。

公开(公告)号：US20080168750A1

公开(公告)日：2008-07-17

申请号：US10568506

申请日：2005-05-09

Applicant: Roberto Trebbi

Inventor： Roberto Trebbi

IPC: A61J3/07 ,  B65B1/38 ,  B65B1/48

CPC classification number: A61J3/074 ,  B65B1/366 ,  B65B1/48

Abstract: A capsule filling machine (100) for the production of hard gelatin capsules (C) of the type with lid (3) and body (2) containing a quantity (1) of pharmaceutical material comprises a rotary turret or carousel (15) which defines at least one capsule (C) handling line (L) and on which the following are positioned, one after the other: at least one station (6) for feeding empty capsules (C); at least one opening station (20) where the capsule bodies (2) are separated from the lids (3) to form two separate rows of capsule bodies (2) and lids (3); at least one station (7) for feeding and dosing the quantities (1) of pharmaceutical material to be filled into the capsule bodies (2); and at least one station (8) for closing the capsules (C) by placing a lid (3) over each respective body (2); the machine (100) also comprises means (9) for detecting and volumetrically checking the quantity (1) of pharmaceutical material filled into each capsule body (2), the detecting and checking means (9) comprise transducer means (5) for measuring the volume of said quantities (1) before they are filled into the capsule bodies (2).

Abstract translation: 用于生产具有盖（3）和包含数量（1）药物材料的盖子（3）和主体（2）的类型的硬明胶胶囊（C）的胶囊填充机（100）包括旋转转盘或转盘（15），其定义 至少一个胶囊（C）处理线（L），并且其上定位有下列物品：至少一个用于供给空胶囊（C）的工位（6）; 至少一个开口站（20），其中所述胶囊主体（2）与所述盖（3）分离以形成两个独立的胶囊体（2）和盖（3）排; 至少一个站（7），用于将要填充的药物材料的数量（1）进料和给药到胶囊体（2）中; 以及至少一个用于通过在每个相应的主体（2）上放置盖子（3）来关闭胶囊（C）的工位（8）。 机器（100）还包括用于检测和体积检查填充到每个胶囊主体（2）中的药物材料的量（1）的装置（9），检测和检查装置（9）包括用于测量 所述量（1）的体积在它们被装入胶囊体（2）之前。

公开(公告)号：US07922798B2

公开(公告)日：2011-04-12

申请号：US11910398

申请日：2006-04-07

Applicant: Salvatore Fabrizio Consoli ,  Andrea Nora ,  Roberto Trebbi

Inventor： Salvatore Fabrizio Consoli ,  Andrea Nora ,  Roberto Trebbi

IPC: B01D46/04

CPC classification number: B01J2/16

Abstract: A granulator device (1) for the treatment of powdered material, in particular pharmaceutical powdered material, comprises a substantially cylindrical container (2), in which there is a chamber (4) for treatment of the powdered material using a fluid flow fed into the chamber (4); filtering means (5) for filtering the inside of the chamber (4), the filtering means (5) being located in the chamber (4) and comprising at least one filter (5) with a cylindrical metal mesh filtering wall (6); and means (P) for cleaning the filtering means (5) which can be activated during maintenance operations, the cleaning means comprising at least one element (7) rotating about each filter (5) and supporting diffuser means (8) designed to diffuse a service fluid on the cylindrical wall (6) in order to eliminate any impurities trapped in the filter (5) wall (6); the cleaning means (P) also comprise means (9) for temporarily opening at least one portion (10) of the filter (5) to allow the service fluid to flow out of the filter (5) together with the impurities.

Abstract translation: 用于处理粉末材料，特别是药物粉末材料的造粒装置（1）包括基本上为圆柱形的容器（2），其中存在用于使用供给到粉末材料的流体流来处理粉末材料的室（4） 室（4）; 过滤装置（5），用于过滤室（4）的内部，过滤装置（5）位于室（4）中，并且包括至少一个具有圆柱形金属网过滤壁（6）的过滤器（5）; 以及用于清洁过滤装置（5）的装置（P），所述清洁装置可在维护操作期间被启动，所述清洁装置包括围绕每个过滤器（5）旋转的至少一个元件（7）和支撑扩散装置（8） 为了消除捕获在过滤器（5）壁（6）中的任何杂质，在圆筒壁（6）上的工作流体; 清洁装置（P）还包括用于临时打开过滤器（5）的至少一部分（10）的装置（9），以允许使用流体与杂质一起流出过滤器（5）。

公开(公告)号：US20080209858A1

公开(公告)日：2008-09-04

申请号：US11996481

申请日：2006-07-24

Applicant: Roberto Trebbi

Inventor： Roberto Trebbi

IPC: B65B1/00

CPC classification number: A61J3/074

Abstract: A capsule filling machine (10) for producing hard gelatin capsules (C) of the type with lid and body (3, 4) containing particles (12) of pharmaceutical material, in particular microtablets (12) or pellets comprises a rotary carousel (2) mounting a plurality of slide units (5) for holding and handling the capsules (C) in order to open and then close the capsules (C) by first separating and then pairing the capsule lids (3) and bodies (4); and means (11) for feeding the particles (12) to the carousel (2) for filling doses of the particles (12) into the respective capsule bodies (4); the feed means (11) comprise at least one hopper (13) containing a mass of these particles (12), and roller means (14) partly immersed in said mass of particles (12) in the hopper (13); the roller means (14) having a plurality of suction recesses (15) for accommodating and retaining a predetermined number of the particles (12) drawn from the hopper (13) and then releasing the particles (12) into a series of hollow conduits (16) mounted on the carousel (2).

Abstract translation: 一种胶囊填充机（10），其用于制造具有盖和主体（3,4）的类型的硬明胶胶囊（C），所述盖体和主体包含药物材料颗粒（12），特别是微片（12）或丸粒，包括旋转圆盘传送带 ）安装多个用于保持和处理胶囊（C）的滑动单元（5），以通过首先分离胶囊盖（3）和主体（4）来打开然后关闭胶囊（C）; 以及用于将颗粒（12）馈送到转盘（2）以将颗粒（12）的剂量填充到各个胶囊体（4）中的装置（11）; 进料装置（11）包括至少一个包含这些颗粒（12）的料斗（13），以及部分地浸入料斗（13）中的所述颗粒（12）中的滚筒装置（14）。 辊装置（14）具有多个吸入凹部（15），用于容纳并保持从料斗（13）拉出的预定数量的颗粒（12），然后将颗粒（12）释放成一系列中空导管（ 16）安装在转盘（2）上。

公开(公告)号：US07395777B2

公开(公告)日：2008-07-08

申请号：US10542954

申请日：2004-02-03

Applicant: Roberto Trebbi

Inventor： Roberto Trebbi

IPC: B05C3/08 ,  B05C5/02

CPC classification number: B05B13/0257 ,  A23G3/26 ,  A61J3/005 ,  B01J2/006 ,  B01J2/12

Abstract: A machine (100) for the treatment of pharmaceutical products (P) comprises a pan (2) that revolves about an axis of rotation (X) and a dispensing unit (3) designed to disperse a coating material inside the pan (2) over a mass (M) of the products (P) located in the pan (2). The pan (2) has an opening (7) for feeding the products to be treated (P) into the pan (2), and an opening (8) for feeding the products (PT) already treated with the coating material out of the pan (2), the infeed opening (7) and the outfeed opening (8) being separate and independent of each other. A portion (K) of the inside surface of the pan (2) is equipped with at least one helical flow regulating fin (4, 5, 6) designed to facilitate inflow (F3) of the products to be treated (P) into the pan (2) during the feeding of the products (P) into the pan (2) through the infeed opening (7) when the pan (2) itself revolves in a first direction of rotation (FI), and to cause outflow (F4) of the treated products (PT) from the pan (2) during the outfeed of the treated products (PT) from the pan (2) through the outfeed opening (8) when the pan (2) itself revolves in a second direction of rotation (F2), opposite to the first direction of rotation (F1).

Abstract translation: 用于治疗药物（P）的机器（100）包括围绕旋转轴线（X）旋转的盘（2）和设计成将覆盖材料分散在盘（2）内部的涂覆材料的分配单元（3） 位于锅（2）中的产品（P）的质量（M）。 盘（2）具有用于将待处理产品（P）进给到锅（2）中的开口（7），以及用于将已经用涂层材料处理的产品（PT）进给的开口（8） 平底锅（2），进料口（7）和出料口（8）彼此分离和独立。 盘（2）的内表面的一部分（K）配备有至少一个螺旋流量调节翅片（4,5,6），其设计成便于待处理产品（P）的流入（F 3）进入 当盘（2）本身沿第一旋转方向（FI）旋转并且引起流出（F）时，通过进料口（7）将产品（P）进给到盘（2）期间的锅（2） 在锅（2）本身在一秒钟内旋转时，处理过的产品（PT）从锅（2）通过出料口（8）出来时从锅（2）处理的处理产品（PT） 旋转方向（F 2），与第一旋转方向（F 1）相反。