公开(公告)号：US20180120553A1

公开(公告)日：2018-05-03

申请号：US15795150

申请日：2017-10-26

Applicant: Scopio Labs Ltd.

Inventor： Ben LESHEM ,  Itai HAYUT ,  Erez NA'AMAN ,  Eran SMALL

IPC: G02B21/36 ,  G02B21/34 ,  G01N21/25 ,  G01N21/17

CPC classification number: G02B21/365 ,  G01N21/17 ,  G01N21/25 ,  G02B21/14 ,  G02B21/34 ,  G02B21/367 ,  G16H30/40

Abstract: Disclosed herein are systems and methods for constructing an image of a sample using a plurality of images acquired under multiple illumination conditions. In some cases, a microscope may include an image capture device, an illumination assembly, and a processor configured to acquire a plurality of images of a sample and a fiducial marker under a plurality of different illumination conditions and to reconstruct a high resolution image in response to the plurality of images. The disclosure also provides a method for generating a high resolution image of a sample comprising acquiring a plurality of images of a sample and a fiducial marker under a plurality of different illumination conditions and reconstructing the high resolution image in response to the plurality of images.