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11.发明申请COMBINATION THERAPY USING BISPECIFIC ANTI-C-MET/ANTI-EGFR ANTIBODY AND C-SRC INHIBITOR 有权使用BISPECIFIC抗C-MET /抗EGFR抗体和C-SRC抑制剂的联合治疗公开(公告)号：US20150216972A1
公开(公告)日：2015-08-06
申请号：US14600986
申请日：2015-01-20
Applicant: Samsung Electronics Co., Ltd.
Inventor： Powei Lin , Kwang Ho Cheong , Young Jun Koh , Jae-woong Hwang , Seung Hyun Lee , Jung Wook Lee
IPC: A61K39/395 , C07K16/30 , A61K31/496 , A61K31/506 , A61K31/517 , C07K16/28 , A61K45/06
CPC classification number: A61K31/496 , A61K31/506 , A61K31/517 , A61K45/06 , A61K2039/505 , C07K16/2863 , C07K2317/24 , C07K2317/31 , C07K2317/56 , C07K2317/622 , C07K2317/73 , C07K2317/92 , A61K2300/00
Abstract: Pharmaceutical composition including a bispecific anti-c-Met/anti-EGFR antibody and a c-Src inhibitor and a method of preventing and/or treating cancer including co-administering a bispecific anti-c-Met/anti-EGFR antibody and a c-Src inhibitor to a subject in need thereof.
Abstract translation: 包含双特异性抗c-Met /抗EGFR抗体和c-Src抑制剂的药物组合物和预防和/或治疗癌症的方法，包括共同施用双特异性抗c-Met /抗EGFR抗体和c -Src抑制剂用于需要的受试者。
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公开(公告)号：US20140356366A1
公开(公告)日：2014-12-04
申请号：US14290447
申请日：2014-05-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho CHEONG , Seung Hyun Lee , Mi Young Cho , Young Jun Koh , Lin Powei , Christina Yi , Jae Woong Hwang
CPC classification number: C07K16/2863 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/53 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: A method of target membrane protein depletion comprising treating a cell with a dual binding molecule comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the cell comprises a cell membrane, and the driver membrane protein and target membrane protein are associated with the cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein; as well as related methods and compositions.
Abstract translation: 一种目标膜蛋白质耗尽的方法，包括用双重结合分子处理细胞，所述双重结合分子包含结合驱动膜蛋白的第一结合结构域和结合靶膜蛋白的第二结合结构域，其中所述细胞包含细胞膜，以及 驱动膜蛋白和靶膜蛋白与靶膜蛋白定位的细胞膜相关联，并且当双重结合分子的第一结合结构域结合驱动膜蛋白时，其被内化为细胞并降解; 以及相关方法和组成。
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13.发明授权公开(公告)号：US10246507B2
公开(公告)日：2019-04-02
申请号：US14869636
申请日：2015-09-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seung Hyun Lee , Soo Yeon Jung , Bo Gyou Kim , Seung Ja Oh , Ji Min Lee
IPC: A61K39/395 , C07K16/22 , C07K16/28 , C07K16/30
Abstract: A polypeptide, an anti-VEGF antibody and an anti-c-Met/anti-VEGF bispecific antibody, which includes the polypeptide, a pharmaceutical composition including the antibody, and a method of treating cancer using the antibody.
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公开(公告)号：US09902776B2
公开(公告)日：2018-02-27
申请号：US14446167
申请日：2014-07-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Mi Young Cho , Seung Hyun Lee , Kwang Ho Cheong , Young Jun Koh , Jung Wook Lee , Powei Lin , Jae Woong Hwang
IPC: C07K16/28 , A61K39/395 , A61K39/00
CPC classification number: C07K16/2863 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/565 , C07K2317/622 , C07K2317/624 , C07K2317/73 , C07K2317/92 , C07K2319/00
Abstract: An anti-EGFR scFV fragment, an anti-c-Met/anti-EGFR bispecific antibody including the same, and a method of preventing and/or treating a cancer using the same are provided.
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公开(公告)号：US09730926B2
公开(公告)日：2017-08-15
申请号：US14600986
申请日：2015-01-20
Applicant: Samsung Electronics Co., Ltd.
Inventor： Powei Lin , Kwang Ho Cheong , Young Jun Koh , Jae-woong Hwang , Seung Hyun Lee , Jung Wook Lee
IPC: A61K31/496 , C07K16/28 , A61K45/06 , A61K31/506 , A61K31/517 , A61K39/00
CPC classification number: A61K31/496 , A61K31/506 , A61K31/517 , A61K45/06 , A61K2039/505 , C07K16/2863 , C07K2317/24 , C07K2317/31 , C07K2317/56 , C07K2317/622 , C07K2317/73 , C07K2317/92 , A61K2300/00
Abstract: Pharmaceutical composition including a bispecific anti-c-Met/anti-EGFR antibody and a c-Src inhibitor and a method of preventing and/or treating cancer including co-administering a bispecific anti-c-Met/anti-EGFR antibody and a c-Src inhibitor to a subject in need thereof.
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Patent Agency Ranking
公开(公告)号：US10934350B2
公开(公告)日：2021-03-02
申请号：US16004622
申请日：2018-06-11
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: A61K39/395 , A61K39/00 , C07K16/22 , G01N33/68 , C07K14/705 , C07K14/515 , A61K38/00
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
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公开(公告)号：US09994632B2
公开(公告)日：2018-06-12
申请号：US14721591
申请日：2015-05-26
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: C07K16/00 , C07K16/28 , C07K16/22 , A61K39/395 , G01N33/68 , C07K14/705 , C07K14/515 , A61K39/00 , A61K38/00
CPC classification number: C07K16/22 , A61K38/00 , A61K39/3955 , A61K2039/505 , C07K14/515 , C07K14/705 , C07K2317/24 , C07K2317/567 , C07K2317/622 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/6887 , G01N33/6893 , G01N2333/515
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
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18.发明授权Yeast cell with inactivated NADH dehydrogenase and method of producing lactate using the yeast cell 有权具有灭活NADH脱氢酶的酵母细胞和使用酵母细胞产生乳酸的方法公开(公告)号：US09556443B2
公开(公告)日：2017-01-31
申请号：US14335728
申请日：2014-07-18
Applicant: Samsung Electronics Co., Ltd.
Inventor： Ju Young Lee , Chang Duk Kang , Jin Kyu Kang , Seung Hyun Lee , Kwang Myung Cho
CPC classification number: C12N15/81 , C12N9/0036 , C12P7/56 , Y02P20/52
Abstract: Provided are a yeast cell in which the activity of an external mitochondrial NADH dehydrogenase is decreased and a method of producing lactate by using the yeast cell.
Abstract translation: 提供了其中外部线粒体NADH脱氢酶的活性降低的酵母细胞和使用酵母细胞产生乳酸盐的方法。
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19.发明申请ANTI-EGFR ANTIBODY AND ANTI-C-MET/ANTI-EGFR BISPECIFIC ANTIBODIES COMPRISING THE SAME 有权抗EGFR抗体和抗C-MET /抗EGFR抗体相似抗体公开(公告)号：US20150030599A1
公开(公告)日：2015-01-29
申请号：US14446167
申请日：2014-07-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Mi Young CHO , Seung Hyun Lee , Kwang Ho Cheong , Young Jun Koh , Jung Wook Lee , Powei Lin , Jae Woong Hwang
IPC: C07K16/28
CPC classification number: C07K16/2863 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/565 , C07K2317/622 , C07K2317/624 , C07K2317/73 , C07K2317/92 , C07K2319/00
Abstract: An anti-EGFR scFV fragment, an anti-c-Met/anti-EGFR bispecific antibody including the same, and a method of preventing and/or treating a cancer using the same are provided.
Abstract translation: 提供抗EGFR scFV片段，包含其的抗c-Met /抗EGFR双特异性抗体，以及使用其的预防和/或治疗癌症的方法。
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20.发明申请YEAST CELL WITH INACTIVATED NADH DEHYDROGENASE AND METHOD OF PRODUCING LACTATE USING THE YEAST CELL 有权具有灭活NADH脱氢酶的YEAST细胞和使用YEAST细胞产生LACTATE的方法公开(公告)号：US20150024444A1
公开(公告)日：2015-01-22
申请号：US14335728
申请日：2014-07-18
Applicant: Samsung Electronics Co., Ltd.
Inventor： Ju Young LEE , Chang Duk Kang , Jin Kyu Kang , Seung Hyun Lee , Kwang Myung Cho
CPC classification number: C12N15/81 , C12N9/0036 , C12P7/56 , Y02P20/52
Abstract: Provided are a yeast cell in which the activity of an external mitochondrial NADH dehydrogenase is decreased and a method of producing lactate by using the yeast cell.
Abstract translation: 提供了其中外部线粒体NADH脱氢酶的活性降低的酵母细胞和使用酵母细胞产生乳酸盐的方法。
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