公开(公告)号：US06312391B1

公开(公告)日：2001-11-06

申请号：US09505587

申请日：2000-02-16

申请人： Satish Ramadhyani ,  Jonathan L. Flachman ,  Eric N. Rudie

发明人： Satish Ramadhyani ,  Jonathan L. Flachman ,  Eric N. Rudie

IPC分类号： A61B500

CPC分类号： A61B5/4375 ,  A61B5/015 ,  A61B2017/00274 ,  A61B2018/00547 ,  A61N5/04

摘要： A non-invasive method of determining a temperature distribution in a targeted tissue volume treated with thermal therapy involves determining a baseline perfusion characteristic of the targeted tissue volume. A temperature distribution is calculated in the targeted tissue volume based on the baseline perfusion characteristic of the tissue, a microwave power input and a coolant temperature input. A perfusion characteristic of the targeted tissue volume is iteratively adjusted based on the calculated temperature distribution, and the temperature distribution is iteratively recalculated based on the adjusted perfusion characteristic, the microwave power input and the coolant temperature input throughout the thermal therapy.

摘要翻译： 确定用热疗法治疗的靶组织体积中的温度分布的非侵入性方法包括确定靶组织体积的基线灌注特征。 基于组织的基线灌注特性，微波功率输入和冷却剂温度输入，在目标组织体积中计算温度分布。 基于计算的温度分布迭代地调整目标组织体积的灌注特性，并且基于经整个热治疗的调整灌注特性，微波功率输入和冷却剂温度输入，迭代地重新计算温度分布。

公开(公告)号：US20120265452A1

公开(公告)日：2012-10-18

申请号：US13086977

申请日：2011-04-14

申请人： Satish Ramadhyani ,  Luan Thien Chan ,  Jason W. Sprain ,  Timothy J. Davis ,  William M. Jacqmein

发明人： Satish Ramadhyani ,  Luan Thien Chan ,  Jason W. Sprain ,  Timothy J. Davis ,  William M. Jacqmein

IPC分类号： G01F1/36 ,  A61B18/02

CPC分类号： A61B18/02 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00863 ,  A61B2018/0287

摘要： The invention is a method for monitoring an amount of gas available in a cryosurgical system used for conducting a cryosurgical procedure. Based on information pertaining to a planned cryosurgical procedure, cryoprobe-specific information for each cryoprobe connected to the cryosurgical system, the specified volumetric capacity of a cryogas source, and measured pressure of the gas in the cryogas source, the method determines the mass flow rates of gas flowing through each cryoprobe, the total mass flow rate of the gas through the cryosurgical system, and the mass of the gas in the cryogas source at standard atmospheric conditions. The amount of time available for completing the cryosurgical procedure before the cryogas source is expended is determined as the arithmetic ratio of the mass of the gas in the cryogas source to the total mass flow rate of the gas through the cryosurgical system.

摘要翻译： 本发明是用于监测用于进行冷冻手术过程的冷冻手术系统中可用的气体量的方法。 根据与计划的冷冻手术程序相关的信息，连接到冷冻手术系统的每个冷冻探针的冷冻探针特异性信息，冷冻源的指定体积容量和冷冻源中气体的测量压力，该方法确定质量流量 流经每个冷冻探针的气体，通过冷冻手术系统的气体的总质量流速，以及在标准大气条件下的冷冻源中的气体质量。 将冷冻源消耗之前完成冷冻手术的时间量确定为冷冻源中的气体质量与通过冷冻手术系统的气体的总质量流量的算术比。