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公开(公告)号：US07785647B2
公开(公告)日：2010-08-31
申请号：US11189216
申请日：2005-07-25
Applicant: Ni Ding
Inventor： Ni Ding
IPC: A61L33/00
CPC classification number: A61L31/10 , Y10T428/1307
Abstract: A method of providing an antioxidant to a medical device is described.
Abstract translation: 描述了向医疗装置提供抗氧化剂的方法。
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12.发明申请公开(公告)号：US20090240325A1
公开(公告)日：2009-09-24
申请号：US12052452
申请日：2008-03-20
Applicant: Shaw Ling Hsu , Yiwen Tang , Lothar W. Kleiner , Fuh-Wei Tang , Ni Ding , Syed Faiyaz Ahmed Hossainy
Inventor： Shaw Ling Hsu , Yiwen Tang , Lothar W. Kleiner , Fuh-Wei Tang , Ni Ding , Syed Faiyaz Ahmed Hossainy
CPC classification number: A61L27/34 , A61L31/10 , A61L2420/08 , C08L67/04
Abstract: Implantable medical device coatings that have improved mechanical stability and medical devices coated with such coatings are disclosed.
Abstract translation: 公开了具有改善的机械稳定性的植入式医疗装置涂层和涂覆有这种涂层的医疗装置。
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公开(公告)号：US20090069883A1
公开(公告)日：2009-03-12
申请号：US12271265
申请日：2008-11-14
Applicant: Ni Ding , W. Scott Andrus
Inventor： Ni Ding , W. Scott Andrus
CPC classification number: A61F2/86 , A61F2250/0068 , A61L31/10 , A61L31/16 , A61L2300/236 , A61L2300/42 , A61L2300/606 , A61M25/104 , A61M2025/105 , A61M2025/1075 , A61M2025/1081
Abstract: The medical devices of the invention comprise an expandable portion which is covered with a sponge coating for release of at least one biologically active material. The sponge coating is made of a non-hydrogel polymer having a plurality of voids. The device can further include means for infusing or expelling the biologically active material or drug into the voids. The drug is delivered to the body lumen of a patient by expelling the drug and inflating or expanding the expandable portion of the catheter or device.
Abstract translation: 本发明的医疗装置包括可膨胀部分，其被海绵涂层覆盖以释放至少一种生物活性材料。 海绵涂层由具有多个空隙的非水凝胶聚合物制成。 该装置还可以包括用于将生物活性材料或药物注入或排出到空隙中的装置。 通过排出药物并使导管或装置的可扩张部分膨胀或膨胀，将药物输送到患者的体腔。
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公开(公告)号：US07462165B2
公开(公告)日：2008-12-09
申请号：US10071400
申请日：2002-02-07
Applicant: Ni Ding , W. Scott Andrus
Inventor： Ni Ding , W. Scott Andrus
IPC: A61M29/00
CPC classification number: A61F2/86 , A61F2250/0068 , A61L31/10 , A61L31/16 , A61L2300/236 , A61L2300/42 , A61L2300/606 , A61M25/104 , A61M2025/105 , A61M2025/1075 , A61M2025/1081
Abstract: The medical devices of the invention comprise an expandable portion which is covered with a sponge coating for release of at least one biologically active material. The sponge coating is made of a non-hydrogel polymer having a plurality of voids. The device can further include means for infusing or expelling the biologically active material or drug into the voids. The drug is delivered to the body lumen of a patient by expelling the drug and inflating or expanding the expandable portion of the catheter or device.
Abstract translation: 本发明的医疗装置包括可膨胀部分，其被海绵涂层覆盖以释放至少一种生物活性材料。 海绵涂层由具有多个空隙的非水凝胶聚合物制成。 该装置还可以包括用于将生物活性材料或药物注入或排出到空隙中的装置。 通过排出药物并使导管或装置的可扩张部分膨胀或膨胀，将药物输送到患者的体腔。
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公开(公告)号：US07413746B2
公开(公告)日：2008-08-19
申请号：US11803810
申请日：2007-05-15
Applicant: Ni Ding
Inventor： Ni Ding
IPC: A61F
CPC classification number: A61K31/4745 , A61L31/10 , A61L31/16 , A61L2300/416 , B82Y30/00 , B82Y40/00 , Y10T428/24
Abstract: A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a self-assembled monolayer.
Abstract translation: 描述了用于医疗装置的涂层，特别是用于药物洗脱支架的涂层。 涂层包括自组装单层。
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Patent Agency Ranking
公开(公告)号：US20070298354A1
公开(公告)日：2007-12-27
申请号：US11820560
申请日：2007-06-19
Applicant: Ni Ding , Gene Michal , Stephen Pacetti
Inventor： Ni Ding , Gene Michal , Stephen Pacetti
CPC classification number: A61L31/16 , A61L31/084 , A61L2300/606
Abstract: A carbon coating on a stent having a bioactive agent covalently attached thereto and methods of making the same are described.
Abstract translation: 描述了具有共价连接于其上的生物活性剂的支架上的碳涂层及其制备方法。
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公开(公告)号：US20070218246A1
公开(公告)日：2007-09-20
申请号：US11803810
申请日：2007-05-15
Applicant: Ni Ding
Inventor： Ni Ding
CPC classification number: A61K31/4745 , A61L31/10 , A61L31/16 , A61L2300/416 , B82Y30/00 , B82Y40/00 , Y10T428/24
Abstract: A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a self-assembled monolayer.
Abstract translation: 描述了用于医疗装置的涂层，特别是用于药物洗脱支架的涂层。 涂层包括自组装单层。
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公开(公告)号：US07232573B1
公开(公告)日：2007-06-19
申请号：US10255911
申请日：2002-09-26
Applicant: Ni Ding
Inventor： Ni Ding
IPC: A61F2/00
CPC classification number: A61K31/4745 , A61L31/10 , A61L31/16 , A61L2300/416 , B82Y30/00 , B82Y40/00 , Y10T428/24
Abstract: A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a self-assembled monolayer.
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公开(公告)号：US20060088654A1
公开(公告)日：2006-04-27
申请号：US11296765
申请日：2005-12-06
Applicant: Ni Ding , Michael Helmus
Inventor： Ni Ding , Michael Helmus
IPC: A61L33/00
CPC classification number: A61F2/82 , A61F2/86 , A61F2/90 , A61F2210/0014 , A61F2250/0067 , A61L27/227 , A61L31/10 , A61L31/141 , A61L31/16 , A61L33/0011 , A61L2300/236 , A61L2300/416 , A61L2300/42 , A61L2300/43 , A61L2300/606 , C08L83/04
Abstract: The present invention is directed to an expandable stent for implantation in a patient comprising a tubular metal body having open ends and a sidewall structure having openings therein and a coating disposed on a surface of said sidewall structure, said coating comprising a hydrophobic biostable elastomeric material and a biologically active material, wherein said coating continuously conforms to said structure in a manner that preserves said openings.
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公开(公告)号：US20050106210A1
公开(公告)日：2005-05-19
申请号：US10989946
申请日：2004-11-16
Applicant: Ni Ding , Michael Helmus
Inventor： Ni Ding , Michael Helmus
IPC: A61F20060101 , A61F2/00 , A61F2/82 , A61F2/86 , A61F2/90 , A61K9/00 , A61L20060101 , A61L27/22 , A61L31/00 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/00 , A61F2/02 , A61F2/06 , B05D3/00
CPC classification number: A61L31/16 , A61F2/82 , A61F2/86 , A61F2/90 , A61F2210/0014 , A61F2250/0067 , A61L27/227 , A61L31/10 , A61L31/141 , A61L33/0011 , A61L2300/222 , A61L2300/236 , A61L2300/406 , A61L2300/42 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2300/622 , A61L2420/02 , C08L71/02 , C08L83/04 , C08L83/00 , C08L83/08 , C08L5/00 , C08L75/04
Abstract: A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologically active species, possibly of controlled average particle size, to form a coating on each stent surface. The coatings are cured in situ and the coated, cured prosthesis are sterilized in a step that includes preferred pretreatment with argon gas plasma and exposure to gamma radiation electron beam, ethylene oxide, steam.
Abstract translation: 公开了一种涂覆可植入的开放格子金属支架假体的方法，其包括依次施加多个相对较薄的涂层组合物的外层，所述涂层组合物包含未固化的聚合物硅氧烷材料和交联剂的溶剂混合物以及细分的生物活性物质，可能是受控的平均颗粒 尺寸，以在每个支架表面上形成涂层。 涂层在原位固化，并且涂覆的固化假体在包括优选的氩气等离子体预处理和暴露于γ射线电子束，环氧乙烷，蒸汽的步骤中被灭菌。
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