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公开(公告)号：US20210276949A1
公开(公告)日：2021-09-09
申请号：US17239191
申请日：2021-04-23
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Yasushi HATTORI , Yuhei MIYANOHANA , Yuichi KAJITA , Tatsuki KOIKE , Yasutaka HOASHI , Norihito TOKUNAGA , Alexander Martin PAWLICZEK , Tsuneo ODA , Tohru MIYAZAKI , Yoshiteru ITO , Kohei TAKEUCHI , Keisuke IMAMURA , Takahiro SUGIMOTO
IPC: C07D207/14 , C07D407/08 , C07D417/06
Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity.
A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.-
公开(公告)号：US20200207715A1
公开(公告)日：2020-07-02
申请号：US16811426
申请日：2020-03-06
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Yuichi Kajita , Yuhei MIYANOHANA , Tatsuki KOIKE , Kohei TAKEUCHI , Yoshiteru ITO , Norihito TOKUNAGA , Takahiro SUGIMOTO , Tohru MIYAZAKI , Tsuneo ODA , Yasutaka HOASHI , Yasushi HATTORI , Keisuke IMAMURA
IPC: C07D211/56 , C07D417/14 , C07D417/06 , C07D413/06 , C07D405/12 , C07D405/10 , C07D403/06 , C07D401/14 , C07D401/10 , C07D401/06 , C07D207/14 , C07D205/04 , A61P25/00 , C07D405/06 , C07D211/36
Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity.A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.
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公开(公告)号：US20200017444A1
公开(公告)日：2020-01-16
申请号：US16577449
申请日：2019-09-20
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Yuichi KAJITA , Satoshi MIKAMI , Yuhei MIYANOHANA , Tatsuki KOIKE , Masaki DAINI , Norio OYABU , Masaki OGINO , Kohei TAKEUCHI , Yoshiteru ITO , Norihito TOKUNAGA , Takahiro SUGIMOTO , Tohru MIYAZAKI , Tsuneo ODA , Yasutaka HOASHI , Yasushi HATTORI , Keisuke IMAMURA
IPC: C07D211/56 , A61P25/00 , C07D205/04 , C07D207/14 , C07D401/06 , C07D401/10 , C07D401/14 , C07D403/06 , C07D405/10 , C07D405/12 , C07D413/06 , C07D417/06 , C07D417/14 , C07D211/36 , C07D405/06
Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity.A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.
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公开(公告)号：US20160176872A1
公开(公告)日：2016-06-23
申请号：US15055108
申请日：2016-02-26
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC: C07D471/04
CPC classification number: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
Abstract translation: 本发明提供具有RORγt抑制作用的杂环化合物。 本发明涉及由式（I）表示的化合物：其中每个符号如说明书中所定义。 或其盐。
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Patent Agency Ranking
公开(公告)号：US20220017514A1
公开(公告)日：2022-01-20
申请号：US17413473
申请日：2019-12-11
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Yuichi KAJITA , Yuhei MIYANOHANA , Tatsuki KOIKE , Yasutaka HOASHI , Yasushi HATTORI , Norihito TOKUNAGA , Tsuneo ODA , Tohru MIYAZAKI , Dilhumar UYGHUR , Yoshiteru ITO , Kohei TAKEUCHI , Keisuke IMAMURA , Takahiro SUGIMOTO , Koichiro FUKUDA , Yasuhisa KOHARA , Rei OKAMOTO , Taiichi OHRA , Naoki MIYAMOTO , Yoshito TERAO , Masanori KAWASAKI
IPC: C07D471/04 , C07D231/56 , C07D277/64 , C07D215/38 , C07D401/14
Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity.
A compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.-
公开(公告)号：US20200207734A1
公开(公告)日：2020-07-02
申请号：US16633960
申请日：2018-08-02
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Yuichi KAJITA , Satoshi MIKAMI , Yuhei MIYANOHANA , Tatsuki KOIKE , Masaki DAINI , Norio OYABU , Masaki OGINO , Kohei TAKEUCHI , Yoshiteru ITO , Norihito TOKUNAGA , Takahiro SUGIMOTO , Tohru MIYAZAKI , Tsuneo ODA , Yasutaka HOASHI , Yasushi HATTORI , Keisuke IMAMURA
IPC: C07D401/06 , C07D211/56 , C07D401/10 , C07D405/10 , C07D207/14 , C07D417/06 , C07D405/12 , C07D409/10 , C07D413/06 , C07D401/14 , C07D205/04 , A61P25/26
Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity.A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.
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17.发明申请公开(公告)号：US20170144973A1
公开(公告)日：2017-05-25
申请号：US15321609
申请日：2015-06-30
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC: C07D217/26 , C07D491/056 , C07D491/048 , C07F7/08 , C07D471/04
CPC classification number: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
Abstract: Provided are heterocyclic compounds having a RORγt inhibitory action represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
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公开(公告)号：US20160176873A1
公开(公告)日：2016-06-23
申请号：US15055156
申请日：2016-02-26
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC: C07D471/04
CPC classification number: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
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公开(公告)号：US20160176822A1
公开(公告)日：2016-06-23
申请号：US15055197
申请日：2016-02-26
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC: C07D217/26
CPC classification number: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
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