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公开(公告)号:US20160176872A1
公开(公告)日:2016-06-23
申请号:US15055108
申请日:2016-02-26
发明人: Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC分类号: C07D471/04
CPC分类号: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
摘要: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
摘要翻译: 本发明提供具有RORγt抑制作用的杂环化合物。 本发明涉及由式(I)表示的化合物:其中每个符号如说明书中所定义。 或其盐。
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公开(公告)号:US20170253591A1
公开(公告)日:2017-09-07
申请号:US15510225
申请日:2015-09-10
发明人: Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Takashi IMADA , Mitsunori KONO , Ayumu SATO , Yoshihide TOMATA , Atsuko OCHIDA , Naoki ISHII , Yusuke SASAKI , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC分类号: C07D471/04 , C07D413/12 , C07D405/12 , C07D405/14 , C07D417/12 , C07D239/96 , C07D409/14 , C07D403/12 , C07D401/12 , C07D417/14 , C07D401/14 , C07D413/14
CPC分类号: C07D471/04 , A61K31/517 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K31/551 , A61P1/00 , A61P11/00 , C07D239/96 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要: The problem of the present invention is to provide a compound having a superior RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like. The present invention relates to a compound represented by the formula (I): [wherein each symbol is as described in the DESCRIPTION] or a salt thereof, which has an RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like.
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公开(公告)号:US20160002169A1
公开(公告)日:2016-01-07
申请号:US14755439
申请日:2015-06-30
发明人: Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC分类号: C07D217/26 , C07D491/056 , C07D491/048 , C07F7/08 , C07D471/04
CPC分类号: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
摘要: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
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4.
公开(公告)号:US20170144973A1
公开(公告)日:2017-05-25
申请号:US15321609
申请日:2015-06-30
发明人: Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC分类号: C07D217/26 , C07D491/056 , C07D491/048 , C07F7/08 , C07D471/04
CPC分类号: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
摘要: Provided are heterocyclic compounds having a RORγt inhibitory action represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
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公开(公告)号:US20170096422A1
公开(公告)日:2017-04-06
申请号:US15127970
申请日:2015-03-23
发明人: Tetsuya TSUKAMOTO , Yoshihisa NAKADA , Michiyo MOCHIZUKI , Takafumi TAKAI , Tomoya YUKAWA , Zenyu SHIOKAWA , Taisuke KATOH , Masaki SETOH , Ayumu SATO , Takafumi YUKAWA
IPC分类号: C07D471/04 , C07D487/04 , C07B59/00 , C07D519/00
CPC分类号: C07D471/04 , C07B59/002 , C07B2200/05 , C07D487/04 , C07D519/00
摘要: Provided is a compound having a superior PKC inhibitory action, and useful as a prophylactic or therapeutic agent for immune diseases, inflammatory diseases and the like, or a salt thereof. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a superior PKC inhibitory action, and is useful as a prophylactic or therapeutic agent for immune diseases, inflammatory diseases and the like.
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公开(公告)号:US20160176873A1
公开(公告)日:2016-06-23
申请号:US15055156
申请日:2016-02-26
发明人: Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC分类号: C07D471/04
CPC分类号: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
摘要: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
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公开(公告)号:US20160176822A1
公开(公告)日:2016-06-23
申请号:US15055197
申请日:2016-02-26
发明人: Satoshi YAMAMOTO , Junya SHIRAI , Tsuneo ODA , Mitsunori KONO , Atsuko OCHIDA , Takashi IMADA , Hidekazu TOKUHARA , Yoshihide TOMATA , Naoki ISHII , Michiko TAWADA , Yoshiyuki FUKASE , Tomoya YUKAWA , Shoji FUKUMOTO
IPC分类号: C07D217/26
CPC分类号: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
摘要: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
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