公开(公告)号：US20160355494A1

公开(公告)日：2016-12-08

申请号：US15117538

申请日：2015-02-12

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Minoru SASAKI ,  Keiko KAKEGAWA ,  Fumiaki KIKUCHI ,  Zenichi IKEDA ,  Yoichi NISHIKAWA

IPC: C07D307/81

CPC classification number: C07D307/81

Abstract: A fused heterocyclic compound having an enteropeptidase inhibitory action and use of the compound as a medicament for treatment or prophylaxis of obesity, diabetes mellitus, etc., are provided. Specifically, a compound represented by the following formula (I): wherein each symbol is as defined herein, or a salt thereof and use of the compound as a medicament for treatment or prophylaxis of obesity, diabetes mellitus, etc., are provided.

公开(公告)号：US20150299188A1

公开(公告)日：2015-10-22

申请号：US14423310

申请日：2013-08-23

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Masaki OGINO ,  Zenichi IKEDA ,  Jun FUJIMOTO ,  Yusuke OHBA ,  Naoki ISHII ,  Takuya FUJIMOTO ,  Tsuneo ODA ,  Naohiro TAYA ,  Toshiro YAMASHITA ,  Nobuyuki MATSUNAGA

IPC: C07D471/04

CPC classification number: C07D471/04 ,  A61K9/2018 ,  A61K9/4858 ,  C07D239/80 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/14 ,  C07D409/12 ,  C07D413/04 ,  C07D417/12 ,  C07D487/04 ,  C07D513/04 ,  C07D519/00

Abstract: Provided is a compound having a superior FLAP inhibitory action and useful as a prophylactic or therapeutic agent for arteriosclerosis and the like, and a salt thereof. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present DESCRIPTION, or a salt thereof.

Abstract translation: 提供具有优异的FLAP抑制作用并可用作动脉硬化等的预防或治疗剂及其盐的化合物。 本发明涉及由下式表示的化合物，其中各符号如本说明书所定义，或其盐。