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    Apparatus and method for delivering a structure to a desired target site
    11.
    发明授权
    Apparatus and method for delivering a structure to a desired target site 有权
    用于将结构传送到期望的目标位置的装置和方法

    公开(公告)号：US09301838B2

    公开(公告)日：2016-04-05

    申请号：US14190324

    申请日：2014-02-26

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia

    IPC: A61F2/24

    CPC classification number: A61F2/243 ,  A61F2/2439 ,  A61F2/2466 ,  A61F2220/0091 ,  A61F2250/0096 ,  A61F2250/0098

    Abstract: An apparatus for delivering an implanted structure to a desired target site within a body lumen of a patient includes a catheter having a longitudinally extending catheter lumen and adapted to provide access to the body lumen. A framing member has a collapsed condition in which the framing member is adapted for insertion into the body lumen through the catheter lumen and an expanded condition in which the framing member is adapted for placement within the body lumen. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. A holding mechanism is carried by the framing member and is adapted to releasably grasp the implanted structure. At least one target pathway is attached to at least one target point. At least a portion of the target pathway extends through the catheter lumen.

    Abstract translation: 用于将植入结构递送到患者的体腔内的期望目标部位的装置包括具有纵向延伸的导管内腔并适于提供对体腔的通路的导管。 框架构件具有折叠状态，其中框架构件适于通过导管内腔插入体腔，并且扩张状态，框架构件适于放置在体腔内。 至少一个目标点由框架构件承载，并适于放置在所需目标位置附近。 保持机构由框架构件承载并适于可释放地把持植入结构。 至少一个目标通路连接至至少一个目标点。 目标通路的至少一部分延伸穿过导管内腔。

    DEVICE, SYSTEM, AND METHOD FOR TREATING A REGURGITANT HEART VALVE
    12.
    发明申请
    DEVICE, SYSTEM, AND METHOD FOR TREATING A REGURGITANT HEART VALVE 审中-公开
    用于治疗心脏瓣膜的装置，系统和方法

    公开(公告)号：US20150359632A1

    公开(公告)日：2015-12-17

    申请号：US14737591

    申请日：2015-06-12

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Jose L. Navia ,  Samir Kapadia

    IPC: A61F2/24

    CPC classification number: A61F2/2454 ,  A61F2/2442 ,  A61F2/2457 ,  A61F2230/0069

    Abstract: In one aspect of the present disclosure, a device for treating a regurgitant heart valve in a subject can include a flexible, elongated body having a central chordae support portion disposed between first and second arms. The first and second arms can include first and second lumens, respectively, extending longitudinally therethrough. A method of treating a regurgitant heart valve in a subject is also provided.

    Abstract translation: 在本公开的一个方面，用于治疗受试者中的反流性心脏瓣膜的装置可以包括柔性细长体，其具有设置在第一和第二臂之间的中心腱索支撑部分。 第一和第二臂可分别包括纵向延伸穿过其中的第一和第二腔。 还提供了治疗受试者的反流心脏瓣膜的方法。

    APPARATUS AND METHOD FOR DELIVERING A STRUCTURE TO A DESIRED TARGET SITE
    16.
    发明申请
    APPARATUS AND METHOD FOR DELIVERING A STRUCTURE TO A DESIRED TARGET SITE 有权
    将结构传递到所需目标站点的装置和方法

    公开(公告)号：US20140243994A1

    公开(公告)日：2014-08-28

    申请号：US14190324

    申请日：2014-02-26

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia

    IPC: A61F2/24

    CPC classification number: A61F2/243 ,  A61F2/2439 ,  A61F2/2466 ,  A61F2220/0091 ,  A61F2250/0096 ,  A61F2250/0098

    Abstract: An apparatus for delivering an implanted structure to a desired target site within a body lumen of a patient includes a catheter having a longitudinally extending catheter lumen and adapted to provide access to the body lumen. A framing member has a collapsed condition in which the framing member is adapted for insertion into the body lumen through the catheter lumen and an expanded condition in which the framing member is adapted for placement within the body lumen. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. A holding mechanism is carried by the framing member and is adapted to releasably grasp the implanted structure. At least one target pathway is attached to at least one target point. At least a portion of the target pathway extends through the catheter lumen.

    Abstract translation: 用于将植入结构递送到患者的体腔内的期望目标部位的装置包括具有纵向延伸的导管内腔并适于提供对体腔的通路的导管。 框架构件具有折叠状态，其中框架构件适于通过导管内腔插入体腔，并且扩张状态，框架构件适于放置在体腔内。 至少一个目标点由框架构件承载，并适于放置在所需目标位置附近。 保持机构由框架构件承载并适于可释放地把持植入结构。 至少一个目标通路连接至至少一个目标点。 目标通路的至少一部分延伸穿过导管内腔。

    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE
    17.
    发明申请
    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE 审中-公开
    装置和方法来达到身体组织

    公开(公告)号：US20140171870A1

    公开(公告)日：2014-06-19

    申请号：US14184763

    申请日：2014-02-20

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia

    IPC: A61B17/34

    CPC classification number: A61B17/3478 ,  A61B34/20 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00278 ,  A61B2017/00292 ,  A61B2017/22038 ,  A61B2017/22077 ,  A61B2017/22095 ,  A61B2017/3405 ,  A61B2017/3411 ,  A61B2017/3484 ,  A61B2018/00392 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61N1/06

    Abstract: An apparatus for targeting a desired target site on a body tissue that separates a first body cavity from a second body cavity of a patient includes a catheter having a longitudinally extending catheter lumen and adapted to provide access to the first body cavity. A framing member has a collapsed condition in which the framing member is adapted for insertion into the first body cavity through the catheter lumen and an expanded condition in which the framing member is adapted for placement within the first body cavity. The framing member has a framing member body. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. At least one target pathway is attached to at least one target point. At least a portion of the target pathway extends through the catheter lumen. The target pathway is substantially spaced apart from the framing member body. A method of using the apparatus is also described.

    Abstract translation: 用于对准将第一体腔与患者的第二体腔分离的身体组织上的期望目标部位的装置包括具有纵向延伸的导管内腔并适于提供对第一体腔的通路的导管。 框架构件具有折叠状态，其中框架构件适于通过导管腔插入第一体腔中，并且扩张状态，其中框架构件适于放置在第一体腔内。 框架构件具有框架构件体。 至少一个目标点由框架构件承载，并适于放置在所需目标位置附近。 至少一个目标通路连接至至少一个目标点。 目标通路的至少一部分延伸穿过导管内腔。 目标路径与框架构件主体基本间隔开。 还描述了使用该装置的方法。

    APPARATUSES FOR AT LEAST PARTIALLY REPAIRING A REGURGITANT HEART VALVE
    19.
    发明申请
    APPARATUSES FOR AT LEAST PARTIALLY REPAIRING A REGURGITANT HEART VALVE 有权

    公开(公告)号：US20250090325A1

    公开(公告)日：2025-03-20

    申请号：US18729534

    申请日：2023-01-18

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Jose Navia ,  Samir Kapadia ,  Torey Hovest

    IPC: A61F2/24

    Abstract: An apparatus for at least partially repairing a regurgitant heart valve includes at least one subvalvular device defining a longitudinal axis and including a subvalvular portion located adjacent a subvalvular cardiac wall adjacent to the heart valve. An anchor portion is adjacent to, and is longitudinally spaced from, the subvalvular portion. A connector neck is interposed longitudinally between, and is attached to both of, the subvalvular portion and the anchor portion. The connector neck penetrates longitudinally through at least one of a base of the first valve leaflet and an annulus of the heart valve at a manufactured puncture site. A fastener is selectively connected to the at least one subvalvular device. The fastener penetrates through at least one of the first and second valve leaflets to maintain the at least one leaflet in a predetermined position with respect to the at least one subvalvular device.

    APPARATUSES AND METHODS FOR AT LEAST PARTIALLY SUPPORTING A VALVE LEAFLET OF A REGURGITANT HEART VALVE
    20.
    发明申请
    APPARATUSES AND METHODS FOR AT LEAST PARTIALLY SUPPORTING A VALVE LEAFLET OF A REGURGITANT HEART VALVE 有权

    公开(公告)号：US20220031456A1

    公开(公告)日：2022-02-03

    申请号：US17396987

    申请日：2021-08-09

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Jose Navia ,  Samir Kapadia ,  Torey Hovest ,  Richard Geoffrion ,  Robert Farnan

    IPC: A61F2/24

    Abstract: An apparatus for partially supporting a leaflet of a regurgitant heart valve includes at least one subvalvular device including a subvalvular supporting portion and an anchor portion. The subvalvular supporting portion and anchor portion are each at least partially formed from at least one of braided mesh strands of a first configuration, braided mesh strands of a second configuration, a balloon, a plurality of longitudinally extending struts, and a plurality of laterally extending struts. A connector neck is interposed longitudinally between, and is attached to both of, the subvalvular supporting portion and the anchor portion. The connector neck penetrates longitudinally through at least one of a base of the leaflet and an annulus of the heart valve at a manufactured puncture site.

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